Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Gregory Fettweis"'
Autor:
Alba Jiménez-Panizo, Andrea Alegre-Martí, Theophilus T Tettey, Gregory Fettweis, Montserrat Abella, Rosa Antón, Thomas A Johnson, Sohyoung Kim, R Louis Schiltz, Israel Núñez-Barrios, Joan Font-Díaz, Carme Caelles, Annabel F Valledor, Paloma Pérez, Ana M Rojas, Juan Fernández-Recio, Diego M Presman, Gordon L Hager, Pablo Fuentes-Prior, Eva Estébanez-Perpiñá
Publikováno v:
Nucleic Acids Res
20 páginas, 7 figuras
The glucocorticoid receptor (GR) is a ubiquitously expressed transcription factor that controls metabolic and homeostatic processes essential for life. Although numerous crystal structures of the GR ligand-binding domain (
The glucocorticoid receptor (GR) is a ubiquitously expressed transcription factor that controls metabolic and homeostatic processes essential for life. Although numerous crystal structures of the GR ligand-binding domain (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::035f1b8140abc8c9d09b095720948efb
https://doi.org/10.1093/nar/gkac1119
https://doi.org/10.1093/nar/gkac1119
Autor:
Gregory Fettweis, Thomas A. Johnson, Brian Almeida-Prieto, Diego M. Presman, Gordon L. Hager, Diego Alvarez de la Rosa
Publikováno v:
bioRxiv
The mineralocorticoid and glucocorticoid receptors (MR and GR) are evolutionary related nuclear receptors with highly conserved DNA- and ligand-binding domains (DBD and LBD), which determine promiscuous activation by corticosteroid hormones (aldoster
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54f7e6c8fd9ca365109bddb866a4742b
https://europepmc.org/articles/PMC9928021/
https://europepmc.org/articles/PMC9928021/
Autor:
Thomas A. Johnson, Gregory Fettweis, Kaustubh Wagh, Brian Almeida-Prieto, Gordon L. Hager, Diego Alvarez de la Rosa
Publikováno v:
bioRxiv
The glucocorticoid and mineralocorticoid receptors (GR and MR, respectively) have distinct, yet overlapping physiological and pathophysiological functions. There is strong indication that both receptors interact both functionally and physically, but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79c8387ff1f429b000ea84236db94bf4
https://doi.org/10.1101/2023.01.26.525745
https://doi.org/10.1101/2023.01.26.525745
Autor:
Kaustubh Wagh, Diana A Stavreva, Rikke AM Jensen, Ville Paakinaho, Gregory Fettweis, R Louis Schiltz, Daniel Wüstner, Susanne Mandrup, Diego M Presman, Arpita Upadhyaya, Gordon L Hager
How transcription factors (TFs) navigate the complex nuclear environment to assemble the transcriptional machinery at specific genomic loci remains elusive. Using single-molecule tracking, coupled with machine learning, we examined the mobility of mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eab9acdd97e164006f26bf28f5e66e6a
https://doi.org/10.1101/2022.07.25.501476
https://doi.org/10.1101/2022.07.25.501476
Autor:
Lorenzo Rinaldi, Gregory Fettweis, Sohyoung Kim, David A. Garcia, Saori Fujiwara, Thomas A. Johnson, Theophilus T. Tettey, Laurent Ozbun, Gianluca Pegoraro, Michele Puglia, Blagoy Blagoev, Arpita Upadhyaya, Diana A. Stavreva, Gordon L. Hager
Publikováno v:
Rinaldi, L, Fettweis, G, Kim, S, Garcia, D A, Fujiwara, S, Johnson, T A, Tettey, T T, Ozbun, L, Pegoraro, G, Puglia, M, Blagoev, B, Upadhyaya, A, Stavreva, D A & Hager, G L 2022, ' The glucocorticoid receptor associates with the cohesin loader NIPBL to promote long-range gene regulation ', Science Advances, vol. 8, no. 13, eabj8360 . https://doi.org/10.1126/sciadv.abj8360
The cohesin complex is central to chromatin looping, but mechanisms by which these long-range chromatin interactions are formed and persist remain unclear. We demonstrate that interactions between a transcription factor (TF) and the cohesin loader NI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72587e746a5c2593402c7b60e367afce
https://doi.org/10.1126/sciadv.abj8360
https://doi.org/10.1126/sciadv.abj8360