Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Gregory F. Pirrone"'
Autor:
Adam J. Fine, Jungchul Kim, Nastaran Salehi Marzijarani, Scott Quirie, Stephen M. Dalby, Tao Wang, Gregory F. Pirrone, Feng Peng, Zhiwei Chen
Publikováno v:
Organic Process Research & Development. 26:525-532
Autor:
Debopreeti Mukherjee, Pablo Trigo‐Mouriño, Yuan Jiang, Timothy Nowak, Vladimir Shchurik, Donovon A. Adpressa, Michael T. Louie, Shane R. Reynolds, Michael J. Hohn, Mohammad Ahmed Al‐Sayah, Gregory F. Pirrone, Alexey A. Makarov
Publikováno v:
Journal of separation scienceREFERENCES. 45(12)
Recent advances in the field of cancer biology have accelerated the discovery and development of novel biopharmaceuticals. At the forefront of these drug development efforts are high-throughput screening, compressed timelines, and limited sample quan
Autor:
Alexey A. Makarov, Yuan Jiang, Christopher Sondey, Minjia Zhang, My Sam Mansueto, Gregory F. Pirrone, Chunhui Huang, Kaustav Biswas, Ruchia Duggal, Mohammad Ahmed Al-Sayah, Erik L. Regalado, Ian Mangion
Publikováno v:
Analytica Chimica Acta. 1225:340234
Peptide therapeutics are a growing modality in the pharmaceutical industry and expanding these therapeutics to hit intracellular targets would require establishing cell permeability. Rapid measurement target-agnostic cell permeability of peptides is
Publikováno v:
Analytica Chimica Acta. 1054:114-121
Biological therapeutics are established as major contributors to the pharmaceutical pipeline. Many of these biological drugs are lyophilized to preserve their conformation and reduce decomposition during storage and shipping. Therefore, understanding
Autor:
Debopreeti Mukherjee, Alexey A. Makarov, Nowak Timothy, Vladimir Shchurik, Gregory F. Pirrone, Mohammad A. Al-Sayah
Publikováno v:
SSRN Electronic Journal.
Autor:
Raffeal Bennett, Ian Mangion, Gregory F. Pirrone, Erik L. Regalado, Debopreeti Mukherjee, Alexey A. Makarov, Timothy Nowak, Claudio Mapelli, Jennifer L. Hickey, Vladimir Shchurik
Publikováno v:
Analytica chimica acta. 1142
At the forefront of synthetic endeavors in the pharmaceutical industry, including drug discovery and high-throughput screening, timelines are tight and large quantities of pure chemical targets are rarely available. In this regard, the development of
Autor:
Edward C. Sherer, Gregory F. Pirrone, John R. Engen, Ian Mangion, Agustina Rodriguez-Granillo, Jeffrey C. Moore, Leo A. Joyce, Roxana E. Iacob, Alexey A. Makarov
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 182
The higher-order structure of a protein defines its function, and protein structural dynamics are often essential for protein binding and enzyme catalysis. Methods for protein characterization in solution are continuously being developed to understan
Autor:
Alexey A. Makarov, Gregory F. Pirrone, Benjamin F. Mann, Erik L. Regalado, Cheng Sun, Timothy Nowak, Shuwen Sun, Heather Wang, Ian Mangion
Publikováno v:
Analytica Chimica Acta. 1018:1-6
Column temperature control is a fundamental component of liquid chromatography experiments. However, it is typically monitored indirectly by tracking the temperature of an adjacent heating element that exchanges heat with the column in a controlled e
Autor:
Eric D. Helms, Heather L. Rudolph, Katelyn P. Lewis, Gregory F. Pirrone, Jordan M. Coffey, Thomas R. Puleo, Troy D. Wood, Amber Flynn-Charlebois, Andrew J. Vadas
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 61:742-748
Stercobilin is an end-stage metabolite of hemoglobin, a component of red blood cells. It has been found that there is a significantly lower concentration of stercobilin in the urine of people diagnosed with autism spectrum disorders, suggesting poten