Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Gregory F. Dolan"'
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142559 (2015)
In support of the RNA world hypothesis, previous studies identified trimetaphosphate (Tmp) as a plausible energy source for RNA world organisms. In one of these studies, catalytic RNAs (ribozymes) that catalyze the triphosphorylation of RNA 5'-hydrox
Externí odkaz:
https://doaj.org/article/8f799bbb928d49acad2b9d3dfde5850e
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86473 (2014)
How does a non-coding RNA evolve in cells? To address this question experimentally we evolved a trans-splicing variant of the group I intron ribozyme from Tetrahymena over 21 cycles of evolution in E.coli cells. Sequence variation was introduced duri
Externí odkaz:
https://doaj.org/article/b377cb67b6cd4aff99797f892a65d256
Publikováno v:
Olson, KE; Dolan, GF; & Müller, UF. (2014). In vivo evolution of a catalytic RNA couples trans-splicing to translation. PLoS ONE, 9(1). doi: 10.1371/journal.pone.0086473. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/3vp64892
PLoS ONE
PloS one, vol 9, iss 1
PLoS ONE, Vol 9, Iss 1, p e86473 (2014)
PLoS ONE
PloS one, vol 9, iss 1
PLoS ONE, Vol 9, Iss 1, p e86473 (2014)
How does a non-coding RNA evolve in cells? To address this question experimentally we evolved a trans-splicing variant of the group I intron ribozyme from Tetrahymena over 21 cycles of evolution in E.coli cells. Sequence variation was introduced duri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4325ce2f22102ce3aa597c7ae78cc66b
http://www.escholarship.org/uc/item/3vp64892
http://www.escholarship.org/uc/item/3vp64892
Autor:
Ulrich Müller, Gregory F. Dolan
Publikováno v:
RNA (New York, N.Y.). 20(2)
Group I introns are ribozymes (catalytic RNAs) that excise themselves from RNA primary transcripts by catalyzing two successive transesterification reactions. These cis-splicing ribozymes can be converted into trans-splicing ribozymes, which can modi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24cbb6f7f082980644c12c77553af68d
https://pubmed.ncbi.nlm.nih.gov/24344321
https://pubmed.ncbi.nlm.nih.gov/24344321