Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Gregory E. R. Gordon"'
Publikováno v:
ChemCatChem. 5:1570-1577
Copyright: 2013 Wiley. This is an ABSTRACT ONLY. The definitive version is published in ChemCatChem, vol. 5(4), pp 1570–1577
Autor:
Godfrey Kupi, M. Jerry Lepuru, Gregory E. R. Gordon, Amanda L. Rousseau, Munaka C. Maumela, Sharon Beemadu, Dean Brady, Duncan M. Sibiya, Arvesh Parsoo, Subash Buddoo
Publikováno v:
Organic Process Research & Development. 15:249-257
Monatin, a natural sweetener, refers to a collection of four isomers of 2-((1H-indol-3-yl)methyl)-4-amino-2-hydroxypentanedioic acid. A chemo-biocatalytic approach to kilogram quantities of enantiopure 2S,4S-monatin and 2R,4R-monatin from indole is d
Autor:
David Richard Walwyn, Jacob G. Zeevaart, M. Jerry Lepuru, Dean Brady, Nasheen Ragubeer, Molala Ratsaka, Moira L. Bode, Daniel F Visser, Gregory E. R. Gordon
Publikováno v:
Organic Process Research & Development. 15:258-265
A chemo-enzymatic method for production of β-thymidine, an intermediate in the synthesis of antiretrovirals, is described. Guanosine and thymine were converted by means of enzymatic transglycosylation to yield 5-methyluridine (5-MU), which was repro
Publikováno v:
Journal of biotechnology. 151(1)
This paper describes a high yielding coupled enzymatic reaction using Bacillus halodurans purine nucleoside phosphorylase (PNP) and E. coli uridine phosphorylase (UP) for synthesis of 5-methyluridine (5-MU) by transglycosylation. Key parameters such