Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Gregory E D Mullen"'
Autor:
Feng Qian, Karine Reiter, Yanling Zhang, Richard L Shimp, Vu Nguyen, Joan A Aebig, Kelly M Rausch, Daming Zhu, Lynn Lambert, Gregory E D Mullen, Laura B Martin, Carole A Long, Louis H Miller, David L Narum
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e36996 (2012)
Self-associated protein aggregates or cross-linked protein conjugates are, in general, more immunogenic than oligomeric or monomeric forms. In particular, the immunogenicity in mice of a recombinant malaria transmission blocking vaccine candidate, th
Externí odkaz:
https://doaj.org/article/2bbd36d8532e439a9dea4bb157f5660b
Autor:
Adam Badar, Sarah DeFreitas, James M McDonnell, Norhakim Yahya, David Thakor, Reza Razavi, Richard Smith, Steven Sacks, Gregory E D Mullen
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18275 (2011)
We describe the design and synthesis of a new Tc-99m labeled bioconjugate for imaging activated complement, based on Short Consensus Repeats 1 and 2 of Complement Receptor 2 (CR2), the binding domain for C3d. To avoid non specific modification of CR2
Externí odkaz:
https://doaj.org/article/84e7b561fd86476baca4b36ec52ba480
Autor:
Richard Tavaré, Pervinder Sagoo, Gopal Varama, Yakup Tanriver, Alice Warely, Sandra S Diebold, Richard Southworth, Tobias Schaeffter, Robert I Lechler, Reza Razavi, Giovanna Lombardi, Gregory E D Mullen
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e19662 (2011)
Dendritic cells (DCs) generated in vitro to present tumour antigens have been injected in cancer patients to boost in vivo anti-tumour immune responses. This approach to cancer immunotherapy has had limited success. For anti-tumour therapy, delivery
Externí odkaz:
https://doaj.org/article/df50062fa02145d1b44b378b066decbf
Autor:
Ruth D Ellis, Laura B Martin, Donna Shaffer, Carole A Long, Kazutoyo Miura, Michael P Fay, David L Narum, Daming Zhu, Gregory E D Mullen, Siddhartha Mahanty, Louis H Miller, Anna P Durbin
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8787 (2010)
Merozoite surface protein 1(42) (MSP1(42)) is a leading blood stage malaria vaccine candidate. In order to induce immune responses that cover the major antigenic polymorphisms, FVO and 3D7 recombinant proteins of MSP1(42) were mixed (MSP1(42)-C1). To
Externí odkaz:
https://doaj.org/article/d9af17dc35c7460eb7acac10989bf905
Autor:
Gregory E D Mullen, Ruth D Ellis, Kazutoyo Miura, Elissa Malkin, Caroline Nolan, Mhorag Hay, Michael P Fay, Allan Saul, Daming Zhu, Kelly Rausch, Samuel Moretz, Hong Zhou, Carole A Long, Louis H Miller, John Treanor
Publikováno v:
PLoS ONE, Vol 3, Iss 8, p e2940 (2008)
Apical Membrane Antigen 1 (AMA1), a polymorphic merozoite surface protein, is a leading blood-stage malaria vaccine candidate. This is the first reported use in humans of an investigational vaccine, AMA1-C1/Alhydrogel, with the novel adjuvant CPG 790
Externí odkaz:
https://doaj.org/article/1cb22ca0776b4320b26f8661467e8b43
Autor:
Alassane Dicko, Issaka Sagara, Ruth D Ellis, Kazutoyo Miura, Ousmane Guindo, Beh Kamate, Moussa Sogoba, Mohamed Balla Niambelé, Mady Sissoko, Mounirou Baby, Amagana Dolo, Gregory E D Mullen, Michael P Fay, Mark Pierce, Dapa A Diallo, Allan Saul, Louis H Miller, Ogobara K Doumbo
Publikováno v:
PLoS ONE, Vol 3, Iss 2, p e1563 (2008)
Apical Membrane Antigen-1 (AMA1) is one of the leading blood stage malaria vaccine candidates. AMA1-C1/Alhydrogel consists of an equal mixture of recombinant AMA1 from FVO and 3D7 clones of P. falciparum, adsorbed onto Alhydrogel. A Phase 1 study in
Externí odkaz:
https://doaj.org/article/fa0e19ee207546599ad83f9354238e50
Autor:
Johanna Pruller, Truc Thuy Pham, Julia E. Blower, Putthiporn Charoenphun, Alessia Volpe, Kavitha Sunassee, Gregory E. D. Mullen, Philip J. Blower, Richard A. G. Smith, Michelle T. Ma
Publikováno v:
RSC Chemical Biology. 4:65-73
An indium-111-labelled peptide binds to myeloma cells, enabling SPECT imaging of myeloma cell accumulation in lungs after intravenous administration. This is the first report of a radiolabelled cell-membrane binding peptide for cell tracking.
Autor:
Philip J. Blower, Margaret S. Cooper, Jennifer D Williams, Gregory E. D. Mullen, Kevin Howland, Adam Badar, Florian Kampmeier
Publikováno v:
Bioconjugate Chemistry. 32:1242-1254
Hexahistidine tags (His-tags), incorporated into recombinant proteins to facilitate purification using metal-affinity chromatography, are useful binding sites for radiolabeling with [99mTc(CO)3]+ and [188Re(CO)3]+ for molecular imaging and radionucli
Autor:
Jennifer D, Williams, Florian, Kampmeier, Adam, Badar, Kevin, Howland, Margaret S, Cooper, Gregory E D, Mullen, Philip J, Blower
Publikováno v:
Bioconjug Chem
Hexahistidine tags (His-tags), incorporated into recombinant proteins to facilitate purification using metal-affinity chromatography, are useful binding sites for radiolabeling with [(99m)Tc(CO)(3)](+) and [(188)Re(CO)(3)](+) for molecular imaging an
Publikováno v:
Journal of Urology. 203
INTRODUCTION AND OBJECTIVE:Medical malpractice (MP) is an important issue in our country. There has been controversy surrounding PSA testing and prostate cancer screening, specifically the United S...