Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Gregory Danko"'
Autor:
Matthew Bratkowski, Tian Xie, Desiree A. Thayer, Shradha Lad, Prakhyat Mathur, Yu-San Yang, Gregory Danko, Thomas C. Burdett, Jean Danao, Aaron Cantor, Jennifer A. Kozak, Sean P. Brown, Xiaochen Bai, Shilpa Sambashivan
Publikováno v:
Cell Reports, Vol 32, Iss 5, Pp 107999- (2020)
Summary: The NADase SARM1 is a central switch in injury-activated axon degeneration, an early hallmark of many neurological diseases. Here, we present cryo-electron microscopy (cryo-EM) structures of autoinhibited (3.3 Å) and active SARM1 (6.8 Å) a
Externí odkaz:
https://doaj.org/article/313bc7f0c8174c0b846a7e9facf8f63c
Publikováno v:
Epilepsy Research. 147:62-70
Childhood absence epilepsy (CAE) is the most common pediatric epilepsy syndrome and is characterized by typical absence seizures (AS). AS are non-convulsive epileptic seizures characterized by a sudden loss of awareness and bilaterally generalized sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03f56e1df3e26a456b19ebb52778fc56
https://doi.org/10.1016/j.eplepsyres.2018.09.007
https://doi.org/10.1016/j.eplepsyres.2018.09.007
Autor:
Xiao Chen Bai, Desiree A. Thayer, Shilpa Sambashivan, Jean Danao, Tian Xie, Jennifer A. Kozak, Matthew Bratkowski, Prakhyat Mathur, Thomas C. Burdett, Sean P. Brown, Gregory Danko, Aaron Cantor, Shradha Lad, Yu San Yang
Publikováno v:
Cell Reports, Vol 32, Iss 5, Pp 107999-(2020)
Summary The NADase SARM1 is a central switch in injury-activated axon degeneration, an early hallmark of many neurological diseases. Here, we present cryo-electron microscopy (cryo-EM) structures of autoinhibited (3.3 A) and active SARM1 (6.8 A) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a8e618a4c2c183c475c8680f4f7ad46
https://doi.org/10.1016/j.celrep.2020.107999
https://doi.org/10.1016/j.celrep.2020.107999