Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Gregory Dame"'
Autor:
Christiane Geithe, Bo Zeng, Carsten Schmidt, Franziska Dinter, Dirk Roggenbuck, Werner Lehmann, Gregory Dame, Peter Schierack, Katja Hanack, Stefan Rödiger
Publikováno v:
Biosensors and Bioelectronics: X, Vol 18, Iss , Pp 100484- (2024)
MicroRNAs (miRNAs) are small non-coding RNA regulators linked to various human diseases incl. heart disease, a leading cause of death in Western countries. Their alterations signify the need for early detection methods. We devised a diffusion microbe
Externí odkaz:
https://doaj.org/article/3940db0b71ff4e249c9144a2fe9ce6ee
Publikováno v:
Microorganisms, Vol 12, Iss 7, p 1285 (2024)
Rapid and accurate detection of Klebsiella pneumoniae carbapenem resistance is important for infection control and targeted antibiotic therapy. PCR-based assay performance heavily depends on the quality and quantity of template DNA. Challenges arise
Externí odkaz:
https://doaj.org/article/533e8cbe59204218b554e71e6cefd556
Autor:
Aline Dorendorf, Iris Bachmann, Martin Spiegel, Ahmed Abd El Wahed, Gregory Dame, Frank Hufert
Publikováno v:
Journal of Clinical Virology Plus, Vol 2, Iss 4, Pp 100115- (2022)
Background: Human coronaviruses are one of the leading causes for respiratory tract infections and for frequent primary care consultation. The human coronavirus NL63 (HCoV..µNL63) is one representative of the seasonal coronaviruses and capable of in
Externí odkaz:
https://doaj.org/article/07d1f3d9cc674894a255bb6bd2e6aa81
Autor:
Ole Behrmann, Matthias Hügle, Peter Bronsert, Bettina Herde, Julian Heni, Marina Schramm, Frank T Hufert, Gerald A Urban, Gregory Dame
Publikováno v:
PLoS ONE, Vol 14, Iss 12, p e0226571 (2019)
We present a simple to operate microfluidic chip system that allows for the extraction of miRNAs from cells with minimal hands-on time. The chip integrates thermoelectric lysis (TEL) of cells with native gel-electrophoretic elution (GEE) of released
Externí odkaz:
https://doaj.org/article/365931d93abd43e6b66f2c0f7e8ac857
Autor:
Ole Behrmann, Matthias Hügle, Franz Eckardt, Iris Bachmann, Cecilia Heller, Marina Schramm, Carrie Turner, Frank T. Hufert, Gregory Dame
Publikováno v:
Micromachines, Vol 11, Iss 6, p 595 (2020)
We investigate the compatibility of three 3D printing materials towards real-time recombinase polymerase amplification (rtRPA). Both the general ability of the rtRPA reaction to occur while in contact with the cured 3D printing materials as well as t
Externí odkaz:
https://doaj.org/article/0fdc8a26845941e188d493e4e710f9b8
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0190041 (2018)
The full potential of the real-time reverse transcription polymerase chain reaction (RT-PCR) as a rapid and accurate diagnostic method is limited by DNA polymerase inhibitors as well as reverse transcriptase inhibitors which are ubiquitous in clinica
Externí odkaz:
https://doaj.org/article/352a57c7feaf434093aacfb39990a28c
Publikováno v:
Proceedings, Vol 1, Iss 4, p 535 (2017)
We present a novel approach for the efficiency enhancement of microfluidic bacteria enrichment systems based on free-flow electrophoresis (FFE). FFE efficiency is highly dependent on the electrophoretic mobility μ of the bacteria. As μ varies stron
Externí odkaz:
https://doaj.org/article/3d5cead0f003444092ef616710b71563
Publikováno v:
Biospektrum
BIOspektrum
BIOspektrum
The COVID-19 pandemic highlights the need for fast and simple assays for nucleic acid detection. As an isothermal alternative to RT-qPCR, we outline the development of a detection scheme for SARS-CoV-2 RNA based on reverse transcription recombinase p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13052fc3e9d8dd460b8711a2ebe4c6e8
http://europepmc.org/articles/PMC7556600
http://europepmc.org/articles/PMC7556600
Publikováno v:
The Analyst. 145:2554-2561
Nucleic acid amplification techniques such as real-time PCR are essential instruments for the identification and quantification of viruses. They are fast, very sensitive and highly specific, but often require elaborate and labor intensive sample prep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42476cb5c0d9980f736ee38ac5e9a618
https://doi.org/10.1039/c9an02333j
https://doi.org/10.1039/c9an02333j
Autor:
Jörg Nestler, Gregory Dame, Werner Lehmann, Peter Schierack, Stefan Rödiger, Franziska Dinter, Michał Burdukiewicz
Publikováno v:
Analytical and Bioanalytical Chemistry
The rapid and simultaneous detection of DNA and protein biomarkers is necessary to detect the outbreak of a disease or to monitor a disease. For example, cardiovascular diseases are a major cause of adult mortality worldwide. We have developed a rapi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fe72d95ca23d55bf28000e41ad74d51
https://doi.org/10.1007/s00216-019-02199-x
https://doi.org/10.1007/s00216-019-02199-x