Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Gregory D. Miles"'
Autor:
Marina Chekmareva, Roman P. Wernyj, Kathleen W. Scotto, Muthu N. Kumaran, Gregory D. Miles, Elaine T. Lim, Karl E. Miletti-González, Michael Reiss, Kyle A. Murphy, Elisa V. Bandera, Swayamjot Kaur, Rigel Chan, Debra S. Heller, David J. Foran, Wenjin Chen, Abhilash K. Ravindranath, Lorna Rodriguez-Rodriguez
Publikováno v:
Journal of Biological Chemistry. 287:18995-19007
CD44 is a multifunctional cell receptor that conveys a cancer phenotype, regulates macrophage inflammatory gene expression and vascular gene activation in proatherogenic environments, and is also a marker of many cancer stem cells. CD44 undergoes seq
Autor:
Michael Reiss, Hilde H. Nienhuis, Whitney Banach-Petrosky, Vidya Ganapathy, Gregory D. Miles, Aparna Kareddula, Wen Xie
Publikováno v:
Clinical & Experimental Metastasis, 29(5), 493-509. SPRINGER
Luminal breast cancer is the most frequently encountered type of human breast cancer and accounts for half of all breast cancer deaths due to metastatic disease. We have developed new in vivo models of disseminated human luminal breast cancer that cl
Publikováno v:
Molecular endocrinology (Baltimore, Md.). 22(5)
Hepatocyte nuclear factor (HNF)-4alpha is a liver-enriched transcription factor that regulates numerous liver-expressed genes including several sex-specific cytochrome P450 genes. Presently, a liver-specific HNF4alpha-deficient mouse model was used t
Autor:
J. Michael Bishop, Sharon R. Pine, Katherine M. Morgan, Xuehui Hong, Elke Markert, Thaddeus D. Allen, Kathleen M. Capaccione, Gregory D. Miles
Publikováno v:
Cancer Research. 74:1149-1149
Sox9 plays critical roles in the specification and differentiation of numerous progenitor and differentiated cell types during embryonic and fetal development. Sox9 is overexpressed in 40 - 50% of lung adenocarcinomas and associated with poor prognos
Publikováno v:
Cancer Research. 71:3777-3777
Autophagy is an evolutionarily conserved process involving protein degradation and organelle recycling, which is essential for cellular homeostasis. Faulty autophagy is linked to tumorigenesis, as Beclin 1 (BECN1), an essential autophagy regulator, i
Publikováno v:
BMC Research Notes
BMC Research Notes, Vol 5, Iss 1, p 164 (2012)
BMC Research Notes, Vol 5, Iss 1, p 164 (2012)
Background MicroRNAs are a class of noncoding RNA molecules that co-regulate the expression of multiple genes via mRNA transcript degradation or translation inhibition. Since they often target entire pathways, they may be better drug targets than gen