Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Gregory D. Ford"'
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
Ischemic stroke is the leading cause of serious long-term disability and the 5th leading cause of death in the United States. Revascularization of the occluded cerebral artery, either by thrombolysis or endovascular thrombectomy, is the only effectiv
Externí odkaz:
https://doaj.org/article/079a6683b7ec434eb27a69e64b194afa
Autor:
Zhenfeng Xu, Gregory D. Ford, DaJoie R. Croslan, Ju Jiang, Alicia Gates, Robert Allen, Byron D. Ford
Publikováno v:
Neurobiology of Disease, Vol 19, Iss 3, Pp 461-470 (2005)
Neuregulins are a family of growth factors with potent neuroprotective properties. We recently demonstrated that neuregulin-1 blocked delayed neuronal death following focal ischemic stroke in the rat. Focal ischemia results in the release of pro-infl
Externí odkaz:
https://doaj.org/article/2dbb8065cf3d40fb8eef5a512ca600e0
Autor:
Zhenfeng Xu, Gregory D. Ford, DaJoie R. Croslan, Ju Jiang, Alicia Gates, Robert Allen, Byron D. Ford
Publikováno v:
Neurobiology of Disease, Vol 31, Iss 2, Pp 286- (2008)
Externí odkaz:
https://doaj.org/article/703bb966f1d04625b75249f9a23cd0f4
Publikováno v:
Journal of molecular neuroscience : MN, vol 69, iss 2
Identifying novel neuroprotectants that can halt or reverse the neurological effects of stroke is of interest to both clinicians and scientists. We and others previously showed the pre-clinical neuroprotective efficacy of neuregulin-1 (NRG-1) in rats
Autor:
Carlos S. Moreno, Virginetta S. Cannon, Zhenfeng Xu, Teclemichael Tewolde, Kyndra C. Stovall, John V.K. Pulliam, Cuimei Liu, Gregory D. Ford, Yonggang Li, Byron D. Ford
Publikováno v:
Brain Research. 1495:76-85
Microarray analysis has been used to understand how gene regulation plays a critical role in neuronal injury, survival and repair following ischemic stroke. To identify the transcriptional regulatory elements responsible for ischemia-induced gene exp
Autor:
Yonggang Li, Gale D. Newman, Lauren J. Simmons, Monique C. Surles-Zeigler, Gregory D. Ford, Byron D. Ford
Publikováno v:
Journal of neuroinflammation, vol 13, iss 1
Journal of Neuroinflammation
Simmons, LJ; Surles-Zeigler, MC; Li, Y; Ford, GD; Newman, GD; & Ford, BD. (2016). Regulation of inflammatory responses by neuregulin-1 in brain ischemia and microglial cells in vitro involves the NF-kappa B pathway. JOURNAL OF NEUROINFLAMMATION, 13. doi: 10.1186/s12974-016-0703-7. UC Riverside: Retrieved from: http://www.escholarship.org/uc/item/5tg0x1d5
Journal of Neuroinflammation
Simmons, LJ; Surles-Zeigler, MC; Li, Y; Ford, GD; Newman, GD; & Ford, BD. (2016). Regulation of inflammatory responses by neuregulin-1 in brain ischemia and microglial cells in vitro involves the NF-kappa B pathway. JOURNAL OF NEUROINFLAMMATION, 13. doi: 10.1186/s12974-016-0703-7. UC Riverside: Retrieved from: http://www.escholarship.org/uc/item/5tg0x1d5
BackgroundWe previously demonstrated that neuregulin-1 (NRG-1) was neuroprotective in rats following ischemic stroke. Neuroprotection by NRG-1 was associated with the suppression of pro-inflammatory gene expression in brain tissues. Over-activation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb654d2b34d8fe30f7846e9aee29ef84
https://escholarship.org/uc/item/5tg0x1d5
https://escholarship.org/uc/item/5tg0x1d5
Autor:
Alicia Gates, Todd E. White, Michelle C. LaPlaca, Benem-Orom Davids, Byron D. Ford, Monique C. Surles-Zeigler, Timothy J. Distel, Gregory D. Ford
Publikováno v:
White, TE; Surles-Zeigler, MC; Ford, GD; Gates, AS; Davids, B; Distel, T; et al.(2016). Bilateral gene interaction hierarchy analysis of the cell death gene response emphasizes the significance of cell cycle genes following unilateral traumatic brain injury. BMC GENOMICS, 17. doi: 10.1186/s12864-016-2412-0. UC Riverside: Retrieved from: http://www.escholarship.org/uc/item/7w48r1rw
BMC genomics, vol 17, iss 1
BMC Genomics
BMC genomics, vol 17, iss 1
BMC Genomics
Background Delayed or secondary cell death that is caused by a cascade of cellular and molecular processes initiated by traumatic brain injury (TBI) may be reduced or prevented if an effective neuroprotective strategy is employed. Microarray and subs
Autor:
Yonggang Li, Catherine Ross-Inta, Cecilia R Giulivi, Cuimei Liu, Gregory D. Ford, Teclemichael Tewolde, Byron D. Ford, Donald A. Bruun, Pamela J. Lein
Publikováno v:
Toxicology and Applied Pharmacology. 262:194-204
Current medical countermeasures against organophosphate (OP) nerve agents are effective in reducing mortality, but do not sufficiently protect the CNS from delayed brain damage and persistent neurological symptoms. In this study, we examined the effi
Autor:
Teclemichael Tewolde, Gregory D. Ford, Pamela J. Lein, Cuimei Liu, Byron D. Ford, Donald A. Bruun, Yonggang Li
Publikováno v:
Toxicology and Applied Pharmacology. 253:261-269
Organophosphate (OP) neurotoxins cause acute cholinergic toxicity and seizures resulting in delayed brain damage and persistent neurological symptoms. Testing novel strategies for protecting against delayed effects of acute OP intoxication has been h
Autor:
Mika A.B. Matthews, Ernest C. Steele, Darryl B. Hood, Alicia Gates, Gregory D. Ford, Byron D. Ford, Sophia Mirza, Peter R. MacLeish
Publikováno v:
Biochemical and Biophysical Research Communications. 377:556-561
The Purkinje cell degeneration (PCD) mutant mouse is characterized by a degeneration of cerebellar Purkinje cells and progressive ataxia. To identify the molecular mechanisms that lead to the death of Purkinje neurons in PCD mice, we used Affymetrix