Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Gregory D. Conway"'
Autor:
Nadire Duru, Nisha R. Pawar, Erik W. Martin, Marguerite S. Buzza, Gregory D. Conway, Rena G. Lapidus, Shihui Liu, Jocelyn Reader, Gautam G. Rao, Dana M. Roque, Stephen H. Leppla, Toni M. Antalis
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(28)
Treatments for advanced and recurrent ovarian cancer remain a challenge due to a lack of potent, selective, and effective therapeutics. Here, we developed the basis for a transformative anticancer strategy based on anthrax toxin that has been enginee
Publikováno v:
The FASEB Journal. 33
Publikováno v:
Current Opinion in Hematology. 23:243-252
The endothelial cell plasma membrane is a metabolically active, dynamic, and fluid microenvironment where pericellular proteolysis plays a critical role. Membrane-anchored proteases may be expressed by endothelial cells as well as mural cells and leu
Autor:
Joseph P. Y. Kao, Marguerite S. Buzza, Kathryn H. Driesbaugh, Erik W. Martin, Toni M. Antalis, Gregory D. Conway
Publikováno v:
Journal of Biological Chemistry. 290:3529-3541
Protease-activated receptors (PARs) are a family of seven-transmembrane, G-protein-coupled receptors that are activated by multiple serine proteases through specific N-terminal proteolytic cleavage and the unmasking of a tethered ligand. The majority
Autor:
Marguerite S. Buzza, Toni M. Antalis, Gregory D. Conway, Erik W. Martin, Subhradip Mukhopadhyay, Tierra A. Johnson, Terez Shea-Donohue
Publikováno v:
The Journal of biological chemistry. 292(26)
Compromised gastrointestinal barrier function is strongly associated with the progressive and destructive pathologies of the two main forms of irritable bowel disease (IBD), ulcerative colitis (UC), and Crohn's disease (CD). Matriptase is a membrane-
Autor:
Erik W. Martin, Marguerite S. Buzza, Toni M. Antalis, Nisha R. Pawar, Gregory D. Conway, Nadire Duru, Tierra A. Johnson, Raymond J. Peroutka
Publikováno v:
J Mol Med (Berl)
Ovarian cancer is the leading cause of death among all the gynecological cancers in the USA. Ovarian cancer employs a unique mode of metastasis, as exfoliated tumor cells disseminate within the peritoneal cavity, colonizing in several sites as well a
Publikováno v:
Glia. 60(12)
The molecular mechanisms controlling human oligodendrocyte development are poorly characterized. Microarray analysis of human oligodendrocyte progenitor cells (OPCs) and immature oligodendrocytes revealed that specific-class I histone deacetylase (HD