Zobrazeno 1 - 10
of 164
pro vyhledávání: '"Gregory D Cartee"'
Autor:
Seong Eun Kwak, Amy Zheng, Edward B Arias, Haiyan Wang, Xiufang Pan, Yongping Yue, Dongsheng Duan, Gregory D Cartee
Publikováno v:
PLoS ONE, Vol 19, Iss 1, p e0295964 (2024)
Some acute exercise effects are influenced by postexercise (PEX) diet, and these diet-effects are attributed to differential glycogen resynthesis. However, this idea is challenging to test rigorously. Therefore, we devised a novel genetic model to mo
Externí odkaz:
https://doaj.org/article/d1c21ce50c554ab58163f4a93c052b51
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0223340 (2020)
The Rab GTPase activating protein known as Akt substrate of 160 kDa (AS160 or TBC1D4) regulates insulin-stimulated glucose uptake in skeletal muscle, the heart, and white adipose tissue (WAT). A novel rat AS160-knockout (AS160-KO) was created with CR
Externí odkaz:
https://doaj.org/article/288efa1091824d848c062b266f080790
Autor:
François Dion, Christopher Dumayne, Nathalie Henley, Stéphanie Beauchemin, Edward B Arias, François A Leblond, Sylvie Lesage, Stéphane Lefrançois, Gregory D Cartee, Vincent Pichette
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0176650 (2017)
Chronic kidney disease is associated with homeostatic imbalances such as insulin resistance. However, the underlying mechanisms leading to these imbalances and whether they promote the development of type 2 diabetes is unknown. The effect of chronic
Externí odkaz:
https://doaj.org/article/79b1025840744f66b9ade14bde48b4d5
Autor:
Naveen Sharma, Donel A Sequea, Carlos M Castorena, Edward B Arias, Nathan R Qi, Gregory D Cartee
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65118 (2014)
Calorie restriction (CR) (consuming ~60% of ad libitum, AL, intake) improves whole body insulin sensitivity and enhances insulin-stimulated glucose uptake by isolated skeletal muscles. However, little is known about CR-effects on in vivo glucose upta
Externí odkaz:
https://doaj.org/article/e63eef2ec5154f4f8e388bc59579aa7b
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38835 (2012)
Moderate calorie restriction (CR) (∼60% of ad libitum, AL, intake) has been associated with numerous favorable physiological outcomes in many species, and the insulin/IGF-1 and mTOR signaling pathways have each been proposed as potential mediators
Externí odkaz:
https://doaj.org/article/b420c8a76e8f4927a8dcd7adacfe8ac1
Autor:
Jamie L Barger, Tsuyoshi Kayo, James M Vann, Edward B Arias, Jelai Wang, Timothy A Hacker, Ying Wang, Daniel Raederstorff, Jason D Morrow, Christiaan Leeuwenburgh, David B Allison, Kurt W Saupe, Gregory D Cartee, Richard Weindruch, Tomas A Prolla
Publikováno v:
PLoS ONE, Vol 3, Iss 6, p e2264 (2008)
Resveratrol in high doses has been shown to extend lifespan in some studies in invertebrates and to prevent early mortality in mice fed a high-fat diet. We fed mice from middle age (14-months) to old age (30-months) either a control diet, a low dose
Externí odkaz:
https://doaj.org/article/e25f222114b3420ba995866183387c34
Publikováno v:
FACETS, Vol 7, Iss , Pp 774-791 (2022)
Attenuated skeletal muscle glucose uptake (GU) has been observed with advancing age. It is important to elucidate the mechanisms linked to interventions that oppose this detrimental outcome. Earlier research using young rodents and (or) cultured myoc
Externí odkaz:
https://doaj.org/article/89b4363a2a87439985c6550f04f9160c
Publikováno v:
Applied Physiology, Nutrition, and Metabolism. 48:283-292
We evaluated effects of calorie restriction (CR; consuming 65% of ad libitum (AL) intake) for 8 weeks on female wildtype (WT) and Akt substrate of 160 kDa knockout (AS160-KO) rats. Insulin-stimulated glucose uptake (ISGU) was determined in isolated e
Autor:
Amy Zheng, Seong Eun Kwak, Jesper B Birk, Edward B Arias, Dominic Thorley, Jørgen F P Wojtaszewski, Gregory D Cartee
Publikováno v:
The journals of gerontology. Series A, Biological sciences and medical sciences.
AMP-activated protein kinase (AMPK), a highly conserved, heterotrimeric serine/threonine kinase with critical sensory and regulatory functions, is proposed to induce antiaging actions of caloric restriction (CR). Although earlier studies assessed CR
Publikováno v:
J Appl Physiol (1985)
One exercise session can increase subsequent insulin-stimulated glucose uptake (ISGU) by skeletal muscle. Prior research on healthy muscle suggests that enhanced postexercise ISGU depends on elevated γ3-AMPK activity leading to greater phosphorylati