Zobrazeno 1 - 10
of 219
pro vyhledávání: '"Gregory D, Gamble"'
Autor:
Min H Chuah, Megan P Leask, Ruth K Topless, Gregory D Gamble, Nicholas A Sumpter, Lisa K Stamp, Tony R Merriman, Nicola Dalbeth
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-15 (2024)
Abstract Background Alcohol consumption is a risk factor for hyperuricaemia and gout. Multiple single-nucleotide polymorphisms (SNPs) have been identified as associated with both alcohol consumption and serum urate or gout in separate genome-wide ass
Externí odkaz:
https://doaj.org/article/18374dbc3e0b4c9eab56923d21d4cba1
Autor:
Nicola Dalbeth, Borislav Mihov, Angela Stewart, Gregory D. Gamble, Tony R. Merriman, David Mount, Ian R. Reid, Lisa K. Stamp, Anne Horne
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract In observational studies, serum urate positively associates with cardiometabolic and kidney diseases. We analyzed data from a randomised placebo-controlled trial to determine whether moderate hyperuricemia induced by inosine affects cardiome
Externí odkaz:
https://doaj.org/article/aaf221767c35411ea02839fd3cee2b47
Autor:
Dorit Naot, Jarome Bentley, Cluny Macpherson, Rocco P. Pitto, Usha Bava, Ally J. Choi, Brya G. Matthews, Karen E. Callon, Ryan Gao, Anne Horne, Gregory D. Gamble, Ian R. Reid, Jillian Cornish
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Population studies in Aotearoa New Zealand found higher bone mineral density and lower rate of hip fracture in people of Polynesian ancestry compared to Europeans. We hypothesised that differences in osteoblast proliferation and differentiat
Externí odkaz:
https://doaj.org/article/bde8389698b942acb81841dc946feb26
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Abstract Early dietary exposure may influence infant appetitive feeding behaviour, and therefore their later health. Maternal diabetes in pregnancy is associated with an increased risk of obesity in the offspring. We, therefore, examined third-trimes
Externí odkaz:
https://doaj.org/article/3301dff36a0f4cd8ab17dabb2eea22c6
Autor:
Nicola Dalbeth, Jordyn Allan, Gregory D. Gamble, Anne Horne, Owen M. Woodward, Lisa K. Stamp, Tony R. Merriman
Publikováno v:
Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-8 (2020)
Abstract Background High body mass index (BMI) is strongly associated with hyperuricaemia. It is unknown whether overweight and obesity influences serum urate primarily through increased urate production or reduced renal clearance of uric acid. The a
Externí odkaz:
https://doaj.org/article/0bea3245720543988d91f44e370a4207
Autor:
Kazi Mirajul Hoque, Eryn E. Dixon, Raychel M. Lewis, Jordyn Allan, Gregory D. Gamble, Amanda J. Phipps-Green, Victoria L. Halperin Kuhns, Anne M. Horne, Lisa K. Stamp, Tony R. Merriman, Nicola Dalbeth, Owen M. Woodward
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
The common ABCG2 variant Q141K contributes to hyperuricemia and gout risk. Here, using a human interventional study and a new orthologous mouse model, the authors report a tissue specific pathobiology of the Q141K variant, and support a significant r
Externí odkaz:
https://doaj.org/article/12c73f6333324432b9f2c84850631506
Autor:
Samson Nivins, Eleanor Kennedy, Benjamin Thompson, Gregory D. Gamble, Jane M. Alsweiler, Russell Metcalfe, Christopher J.D. McKinlay, Jane E. Harding
Publikováno v:
NeuroImage: Clinical, Vol 33, Iss , Pp 102943- (2022)
Neonatal hypoglycaemia is a common metabolic disorder that may cause brain damage, most visible in parieto-occipital regions on MRI in the acute phase. However, the long term effects of neonatal hypoglycaemia on the brain are not well understood. We
Externí odkaz:
https://doaj.org/article/657d5235d7b74626929bbb35d0cc52f5
Publikováno v:
BMC Rheumatology, Vol 3, Iss 1, Pp 1-9 (2019)
Abstract Background Methods of gout flare reporting in research settings are inconsistent and poorly defined. The aim of this study was to describe patterns of gout flare and assess the concurrent validity of different methods of flare reporting in a
Externí odkaz:
https://doaj.org/article/32d48f3efa1147eab6bd32ccd4dad5a3
Autor:
Rachel Murdoch, Anna Mellar, Anne M. Horne, Emma Billington, Pui Ling Chan, Gregory D. Gamble, Ian R. Reid
Publikováno v:
Journal of Bone and Mineral Research. 38:631-638
Autor:
Jane E Harding, Joanne E Hegarty, Caroline A Crowther, Richard P Edlin, Gregory D Gamble, Jane M Alsweiler, hPOD Study Group
Publikováno v:
PLoS Medicine, Vol 18, Iss 1, p e1003411 (2021)
BackgroundNeonatal hypoglycemia is common and can cause brain injury. Buccal dextrose gel is effective for treatment of neonatal hypoglycemia, and when used for prevention may reduce the incidence of hypoglycemia in babies at risk, but its clinical u
Externí odkaz:
https://doaj.org/article/0f58d4b05842409da6224aa6b1fa33d7