Výsledky vyhledávání - "Gregory Cooksey Rigdon"

Novel inhibitors of the Gardos channel for the treatment of sickle cell disease

Autor: Jonathan W. Stocker, Lucia De Franceschi, Grant A McNaughton-Smith, J Ford Burns, Gregory Cooksey Rigdon, Tara Shelton, Christopher Creech, Susan Arrington

Publikováno v: Journal of medicinal chemistry. 51(4)

Sickle cell disease (SCD) is a hereditary condition characterized by deformation of red blood cells (RBCs). This phenomenon is due to the presence of abnormal hemoglobin that polymerizes upon deoxygenation. This effect is exacerbated when dehydrated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52785fc3214275905e515ac31dd4eb03
https://pubmed.ncbi.nlm.nih.gov/18232633

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Structure-activity relationships of a series of substituted benzamides: potent D2/5-HT2 antagonists and 5-HT1a agonists as neuroleptic agents

Autor: Navas F rd, Gregory Cooksey Rigdon, William R. Hall, Mark H. Norman

Publikováno v: Journal of medicinal chemistry. 39(5)

A series of substituted (4-(4-(1,2-benzisothiazol-3-yl)-1-piperazinyl)butyl)benzamide derivatives was prepared and evaluated as potential atypical antipsychotic agents. The target compounds were readily prepared from their benzoyl chloride, benzoic a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e1b70e814776ef032a848203c473603
https://pubmed.ncbi.nlm.nih.gov/8676355

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