Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Gregory Cesarone"'
Autor:
Guylaine Roy, Pratik Kadekar, Lynn Marie Douglas, Maude Frappier, Jean-Christophe Currie, Jess Dhillon, Gregory Cesarone, Richard Siderits, Karen Kirchner, Michel Demeule, Christian Marsolais
Publikováno v:
Cancer Research. 83:3942-3942
Sortilin (SORT1), or neurotensin receptor-3, is a scavenging receptor in the Vacuolar Protein Sorting 10 protein (Vps10p) family. SORT1 is involved in the internalization and trafficking of its ligands through an endocytic process and is associated w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d35d9dbb1d78196939d5938ee50138db
https://doi.org/10.1158/1538-7445.am2023-3942
https://doi.org/10.1158/1538-7445.am2023-3942
Publikováno v:
Cancer Research. 83:2763-2763
Introduction: Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) is expressed on the surface of some tumor epithelial cells and is a potential therapeutic target for antibody-drug conjugates such as tusamitamab ravtansine in developm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6eb84004bd74633c6b8ab9ee7921b3d7
https://doi.org/10.1158/1538-7445.am2023-2763
https://doi.org/10.1158/1538-7445.am2023-2763
Autor:
Elena A. Goncharova, Vera P. Krymskaya, Gregory Cesarone, Matthew Spaits, Omar Tliba, Amelia Chisolm, Reynold A. Panettieri, Dmitry A. Goncharov, Irene Khavin, Poay N. Lim, Yassine Amrani
Publikováno v:
Molecular Pharmacology. 73:778-788
Lymphangioleiomyomatosis (LAM), a rare pulmonary disorder, manifests as an abnormal neoplastic growth of smooth muscle-like cells within the lungs. Mutational inactivation of tumor suppressor tuberous sclerosis complex 2 (TSC2) in LAM constitutively
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af9d32e3a8a7365e69c3980711317f7d
https://doi.org/10.1124/mol.107.040824
https://doi.org/10.1124/mol.107.040824
Publikováno v:
Bioconjugate Chemistry. 18:1831-1840
IRS-1 overexpression has been associated with breast cancer development, hormone independence and antiestrogen resistance. IRS-1 is a major downstream signaling protein for insulin and IGF1 receptors, conveying signals to PI-3K/Akt and ERK1/2 pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec6d0a4ff6e9cff17cf3c4efc98def05
https://doi.org/10.1021/bc070135v
https://doi.org/10.1021/bc070135v
Autor:
Eric Wickstrom, Eva Surmacz, Olga Igoucheva, Gregory Cesarone, Vitali Alexeev, Kyonggeun Yoon, Marc T. Abrams, Cecilia Garofalo
Publikováno v:
Journal of Cellular Biochemistry. 98:440-450
Insulin receptor substrate 1 (IRS-1) is a major downstream signaling protein for insulin and insulin-like growth factor I (IGF-I) receptors, conveying signals to PI-3K/Akt and ERK1/2 pathways. In breast cancer, IRS-1 overexpression has been associate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b521c28f8193befa7a7274b671e2a663
https://doi.org/10.1002/jcb.20817
https://doi.org/10.1002/jcb.20817
Autor:
Shaoxin Lu, Kasif Taker, Eric Wickstrom, Kousik Sivakumar, Gregory Cesarone, Balaji Panchapakesan
Publikováno v:
NanoBiotechnology. 1:133-140
We report the first application of single-wall carbon nanotubes (SWCNT) as potent therapeutic nanobomb agents for killing breast cancer cells. We show here that by adsorbing water molecules in SWCNT sheets or loosely adsorbed on top of cells, potent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf0b109e67df304d0ebba9839c237b4d
https://doi.org/10.1385/nbt:1:2:133
https://doi.org/10.1385/nbt:1:2:133
Publikováno v:
NanoBiotechnology. 1:353-360
Monoclonal antibodies (mAb) specific to cell surface antigens overexpressed on cancer cells adsorbed to single-wall carbon nanotube (SWCNT) devices can bind to their antigens in a drop of buffer, resulting in a slight drop in conductance. Here we rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78d4f309daccbf4084919547a147a3fd
https://doi.org/10.1385/nbt:1:4:353
https://doi.org/10.1385/nbt:1:4:353
Autor:
Janice Dispoto, Andrew F.X. Goldberg, Gregory Cesarone, Kathleen Boesze-Battaglia, Arlene D. Albert, Madan Katragadda
Publikováno v:
Experimental Eye Research. 77:505-514
Photoreceptor rod cells contain a unique tetraspanin fusion protein known as peripherin/rds. This protein is important in membrane fusion events hypothesized to be essential to disk membrane morphogenesis and disk shedding. In vivo and in vitro fusog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18f790dc0297b24f14088c5efa8a4ac2
https://doi.org/10.1016/s0014-4835(03)00151-9
https://doi.org/10.1016/s0014-4835(03)00151-9
Autor:
Poay N. Lim, Jennifer Snow, Dmitry A. Goncharov, Elena A. Goncharova, Irene Khavin, Vera P. Krymskaya, Gregory Cesarone, Kaori Ihida-Stansbury, Peter L. Jones, Sigrid C. Veasey
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 25(6)
Pulmonary arterial vascular smooth muscle (PAVSM) cell proliferation is a key pathophysiological component of vascular remodeling in pulmonary arterial hypertension (PAH) for which cellular and molecular mechanisms are poorly understood. The goal of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea880e7878f6c92087972ee91e4fe336
https://pubmed.ncbi.nlm.nih.gov/21368105
https://pubmed.ncbi.nlm.nih.gov/21368105
Autor:
Kaijun Zhang, Christopher Cardi, Mohan R. Aruva, Mathew L. Thakur, Gregory Cesarone, Nylla Shanthly, Satish Rattan, Eric Wickstrom, Chirag A. Patel
Publikováno v:
Regulatory peptides. 144(1-3)
Vasoactive intestinal peptide and pituitary adenylate cyclase activating peptide have high affinity for VPAC1, VPAC2 and PAC1 receptors overexpressed on human cancer cells. Four potent analogues of these peptides, TP3939, TP3982, TP4200 and TP3805 we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::250018859ed4efccaa67f86faf309699
https://pubmed.ncbi.nlm.nih.gov/17727979
https://pubmed.ncbi.nlm.nih.gov/17727979