Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Gregory C. Gaines"'
Autor:
Amer Abouhamze, Jill Gasser, Lyle L. Moldawer, J. Frazier, Tadahiko Kohno, Angela Nelson, Carl K. Edwards, Steven W. Martin, William J. Boyle, James Ervin Seely, Olaf B Kinstler, Gary L. Kieft, Jeff Rose, Jason J. Rosenberg, Kunitaro Fukuzuka, William Marshall, Gregory C. Gaines, Ulrich Feige, Judy St. Clair
Publikováno v:
Journal of Applied Physiology. 91:2213-2223
Pharmacokinetics and immunogenicity of six different recombinant human soluble p55 tumor necrosis factor (TNF) receptor I (sTNFR-I) constructs were evaluated in juvenile baboons. The constructs included either an sTNFR-I IgG1 immunoadhesin (p55 sTNFR
Autor:
Thomas S. Huber, Lyle L. Moldawer, Jason J. Rosenberg, James M. Seeger, M B Welborn rd, Gregory C. Gaines
Publikováno v:
Shock. 13:425-434
The results of recent anticytokine trials for sepsis syndrome have been disappointing. Several Phase II and Phase III clinical trials have shown a modest benefit in various subsets of patients; however, there has been no reported benefit in the prima
Autor:
Sean Lee, Lyle L. Moldawer, Rebecca M. Minter, John E. Rectenwald, Gregory C. Gaines, Jason J. Rosenberg
Publikováno v:
Shock (Augusta, Ga.). 17(2)
Bioglass is a bioactive, resorbable ceramic particle that was developed to assure binding to living tissues. Bioglass is currently employed to fill osseus defects in oral surgery, and it possesses both unique anti-inflammatory and antimicrobial prope
Autor:
Rebecca M. Minter, Lyle L. Moldawer, Gregory C. Gaines, Frances R. Bahjat, Carl K. Edwards, John E. Rectenwald, Jason J. Rosenberg, Sally L. D. MacKay, Monika Nowak
Publikováno v:
American journal of physiology. Regulatory, integrative and comparative physiology. 278(5)
Lipopolysaccharide and D-galactosamine induced lethality and apoptotic liver injury is dependent on endogenously produced tumor necrosis factor (TNF)-alpha. The present study was undertaken to determine whether membrane-associated or secreted TNF-alp
Autor:
James M. Seeger, Lyle L. Moldawer, Gregory C. Gaines, Thomas S. Huber, M.Burress Welborn, Timothy R.S. Harward
Publikováno v:
Journal of vascular surgery. 29(2)
Purpose: Tumor necrosis factor α (TNF-α) has been shown to play a role in pulmonary injury after lower-extremity ischemia/reperfusion (I/R). However, its role in direct skeletal muscle injury is poorly understood. The hypothesis that endogenous TNF
Autor:
Lyle L. Moldawer, Gregory C. Gaines, Kunitaro Fukuzuka, Michael J. Clare-Salzler, Edward M. Copeland, Carl K. Edwards, David W. Mozingo, Sally L. D. MacKay, Jason J. Rosenberg
Publikováno v:
Annals of Surgery. 229:851
Objective To examine the role played by endotoxin, tumor necrosis factor-alpha (TNF-α), and caspase-3 in the increased apoptosis seen in solid organs in the early period after a burn injury. Background Data Burn injury is often associated with immun