Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Gregory Batt"'
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Optimizing the production of recombinant proteins is a problem of major industrial and pharmaceutical importance. Secretion of the protein by the host cell considerably simplifies downstream purification processes. However, for many proteins
Externí odkaz:
https://doaj.org/article/9101ca7eba1f4167ba2f87cba492c34a
Autor:
François Bertaux, Sebastián Sosa-Carrillo, Viktoriia Gross, Achille Fraisse, Chetan Aditya, Mariela Furstenheim, Gregory Batt
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Small-scale bioreactors are increasingly used in quantitative biology. Here, the authors report ReacSight, a software solution to connect reactor arrays with sensitive measurement devices using low-cost pipetting robots and provide applications lever
Externí odkaz:
https://doaj.org/article/5b144b6eba054bb8a1359d205403f63a
Autor:
Zachary R. Fox, Steven Fletcher, Achille Fraisse, Chetan Aditya, Sebastián Sosa-Carrillo, Julienne Petit, Sébastien Gilles, François Bertaux, Jakob Ruess, Gregory Batt
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-8 (2022)
In microscopy, applications in which reactiveness is needed are multifarious. Here the authors report MicroMator, a Python software package for reactive experiments, which they use for applications requiring real-time tracking and light-targeting at
Externí odkaz:
https://doaj.org/article/3bc80086b5de48f6bcbae6396a5613e1
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Artificial microbial consortia use division-of-labour to optimize production. Here the authors develop an optogenetic differentiation system in yeast to generate consortia from a single strain with tunable composition.
Externí odkaz:
https://doaj.org/article/540ce59a5ca2421cacf952d00a3e20f4
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 3, p e1009950 (2022)
Understanding and characterising biochemical processes inside single cells requires experimental platforms that allow one to perturb and observe the dynamics of such processes as well as computational methods to build and parameterise models from the
Externí odkaz:
https://doaj.org/article/e7dc8f57714a4606bd0b647eb1451fc7
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 7, p e1009214 (2021)
The chemical master equation and its continuum approximations are indispensable tools in the modeling of chemical reaction networks. These are routinely used to capture complex nonlinear phenomena such as multimodality as well as transient events suc
Externí odkaz:
https://doaj.org/article/4b872ddcf3104a8c8a77ca4519d77ae8
To quarantine, or not to quarantine: A theoretical framework for disease control via contact tracing
Publikováno v:
Epidemics, Vol 34, Iss , Pp 100428- (2021)
Contact tracing via smartphone applications is expected to be of major importance for maintaining control of the COVID-19 pandemic. However, viable deployment demands a minimal quarantine burden on the general public. That is, consideration must be g
Externí odkaz:
https://doaj.org/article/5094f9675fed40df96234415e43f168e
Autor:
Jean-Baptiste Lugagne, Sebastián Sosa Carrillo, Melanie Kirch, Agnes Köhler, Gregory Batt, Pascal Hersen
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
Cybergenetics aims to monitor and regulate cellular processes in real-time using computer monitoring and feedback of biological readouts. Here the authors use a feedback loop and periodic forcing to maintain cells with a bistable synthetic circuit ne
Externí odkaz:
https://doaj.org/article/c27529a75daa46a5bb91afbce34bb1dc
Autor:
Artémis Llamosi, Andres M Gonzalez-Vargas, Cristian Versari, Eugenio Cinquemani, Giancarlo Ferrari-Trecate, Pascal Hersen, Gregory Batt
Publikováno v:
PLoS Computational Biology, Vol 12, Iss 2, p e1004706 (2016)
Significant cell-to-cell heterogeneity is ubiquitously observed in isogenic cell populations. Consequently, parameters of models of intracellular processes, usually fitted to population-averaged data, should rather be fitted to individual cells to ob
Externí odkaz:
https://doaj.org/article/e1b73a35ea7c40c296bf17a23fd25693
Publikováno v:
PLoS Computational Biology, Vol 10, Iss 10, p e1003893 (2014)
Isogenic cells sensing identical external signals can take markedly different decisions. Such decisions often correlate with pre-existing cell-to-cell differences in protein levels. When not neglected in signal transduction models, these differences
Externí odkaz:
https://doaj.org/article/dff2d1d477814014a530c09e09f25eab