Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Gregory Bannish"'
Publikováno v:
Expert opinion on biological therapy. 22(1)
Introduction: Immunotherapies are focused on strategies that alter immune responses, using antibodies that binds to receptors on different immune cell subsets and either activate or suppress their functions depending on the immune response being targ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b335cbdd9359fd0a991a2fa9e1f24264
https://pubmed.ncbi.nlm.nih.gov/34139906
https://pubmed.ncbi.nlm.nih.gov/34139906
Autor:
Heeringa Katharine, Allison R. Greenplate, Meredith Perpetua, Randall J. Brezski, Gregory Bannish, Robert Jordan, Frank Lynch, Stephen G. McCarthy, Katharine D. Grugan, Michelle Kinder, William R. Strohl, Keri L. Soring
Publikováno v:
Journal of Biological Chemistry. 288:30843-30854
Molecularly engineered antibodies with fit-for-purpose properties will differentiate next generation antibody therapeutics from traditional IgG1 scaffolds. One requirement for engineering the most appropriate properties for a particular therapeutic a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15ac0b3bd9a3b0710d27bc695d73ab29
https://doi.org/10.1074/jbc.m113.486142
https://doi.org/10.1074/jbc.m113.486142
Publikováno v:
Bioanalysis. 3:2657-2663
The induction of cytokine release is a common consequence of the administration of therapeutic antibodies and in most cases is either tolerated by the patient or can be managed clinically by the administration of corticosteroids. However, in 2006, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32684ddb2f6a6da96e278a1fe01fa3e6
https://doi.org/10.4155/bio.11.272
https://doi.org/10.4155/bio.11.272
Autor:
Theodora W. Salcedo, Daniel Weinstock, Gregory Bannish, Patricia C. Ryan, Carol S. Auletta, Thulasi Ramani, Barbara Mounho-Zamora
Publikováno v:
International journal of toxicology. 34(4)
Over the past 30 years, the world of pharmaceutical toxicology has seen an explosion in the area of cytokines. An overview of the many aspects of cytokine safety evaluation currently in progress and evolving strategies for evaluating these important
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::940bc2f01f52563fbad444e82fbfe87c
https://pubmed.ncbi.nlm.nih.gov/26015504
https://pubmed.ncbi.nlm.nih.gov/26015504
Publikováno v:
Immunological Reviews. 197:26-40
B-cell development is a highly ordered multistep process dependent upon signals generated by the pre-B and B-cell antigen receptor (BCR). BCR signals drive maturation of the B cell by integrating a number of parallel and sequential biological process
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc208b472dcfa34e5ebedd1d42199516
https://doi.org/10.1111/j.0105-2896.2004.0105.x
https://doi.org/10.1111/j.0105-2896.2004.0105.x
Autor:
Peter C. Sandel, James B. Chung, Ezequiel M. Fuentes-Pananá, John G. Monroe, Gregory Bannish, Leslie B. King, Richard A. Sater
Publikováno v:
Immunologic Research. 27:427-442
Our laboratory is interested in a variety of issues related to lymphocyte development. More specifically, we have focused on the processes that regulate the decision to commit to the B lymphocyte (B cell) lineage, then the subsequent signals that are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f10f141ead8376ef28a6e7b7c98dab7e
https://doi.org/10.1385/ir:27:2-3:427
https://doi.org/10.1385/ir:27:2-3:427
Publikováno v:
The Journal of Experimental Medicine
Signal transduction through the B cell antigen receptor (BCR) is determined by a balance of positive and negative regulators. This balance is shifted by aggregation that results from binding to extracellular ligand. Aggregation of the BCR is necessar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97761e78fc5c60f2bee179aaa7021633
https://doi.org/10.1084/jem.194.11.1583
https://doi.org/10.1084/jem.194.11.1583
Publikováno v:
Toxicology Letters. 229:S205-S206
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1cb48f1b805f1349509085996aaf9461
https://doi.org/10.1016/j.toxlet.2014.06.692
https://doi.org/10.1016/j.toxlet.2014.06.692
Autor:
Cindy Duchala, Ashlyn Bassiri, Jamie Fisher, Gregory Bannish, Michael A. Rycyzyn, Kimberly Staquet, Jill Giles-Komar
Publikováno v:
Hybridoma (2005). 27(1)
Herein we describe the use of an agonistic anti-murine CD40 MAb as a B cell proliferative agent to enhance the generation of monoclonal antibodies (MAbs) in Balb/c mice. While hybridoma technology has been validated repeatedly over the decades, littl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94ba8bd8a7a3ba83fadda745233e9756
https://pubmed.ncbi.nlm.nih.gov/18294073
https://pubmed.ncbi.nlm.nih.gov/18294073
Publikováno v:
Immunological reviews. 218
The presence of an immunoreceptor tyrosine-based activation motif (ITAM) makes immunoreceptors different from other signaling receptors, like integrins, G-coupled protein receptors, chemokine receptors, and growth factor receptors. This unique motif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::285fbc81b47e2ceaaeda6d0acacf35e5
https://pubmed.ncbi.nlm.nih.gov/17624955
https://pubmed.ncbi.nlm.nih.gov/17624955