Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Gregory B. Holmes"'
Autor:
Gregory B. Holmes, Gregory L. Kearns, Neil Manowitz, Franklin K. Johnson, Susan M. Abdel-Rahman
Publikováno v:
The Journal of Clinical Pharmacology. 42:1089-1096
The pharmacokinetics of nizatidine following a single 5.0 mg/kg oral dose given as an extemporaneous liquid formulation in apple juice was examined in 12 healthy children (8.0 +/- 2.4 years, 30.7 +/- 8.4 kg). Nizatidine and N-desmethylnizatidine were
Autor:
Susan M, Abdel-Rahman, Franklin K, Johnson, Neil, Manowitz, Gregory B, Holmes, Gregory L, Kearns
Publikováno v:
Journal of Clinical Pharmacology. 42:1089-1096
The pharmacokinetics of nizatidine following a single 5.0 mg/kg oral dose given as an extemporaneous liquid formulation in apple juice was examined in 12 healthy children (8.0 +/- 2.4 years, 30.7 +/- 8.4 kg). Nizatidine and N-desmethylnizatidine were
Autor:
Arturo G. Porras, Jutta L. Miller, David L. Ebel, J. S. Redfern, Gregory B. Holmes, Nancy G. B. Agrawal, Marshall Sack, Jules I. Schwartz, Barry J. Gertz, Kenneth Bachmann, Peggy H. Wong
Publikováno v:
The Journal of Clinical Pharmacology. 41:1120-1130
Rofecoxib is a highly selective and potent inhibitor of cyclooxgenase-2 (COX-2). Methotrexate is a disease-modifying agent with a narrow therapeutic index frequently prescribed for the management of rheumatoid arthritis. The objective of this study w
Autor:
Pirow J, Bekker, Donna L, Holloway, Amy S, Rasmussen, Robyn, Murphy, Steven W, Martin, Philip T, Leese, Gregory B, Holmes, Colin R, Dunstan, Alex M, DePaoli
Publikováno v:
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 20(12)
Autor:
Colin R. Dunstan, Philip T. Leese, Donna Holloway, Pirow Bekker, Amy S Rasmussen, Steven W. Martin, Robyn Murphy, Gregory B Holmes, Alex M. DePaoli
Publikováno v:
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 19(7)
The safety and bone antiresorptive effect of a single subcutaneous dose of AMG 162. a human monoclonal antibody to RANKI,, was investigated in 49 postmenopausal women. AMG 162 is a potent antiresorptive agent for diseases such as osteoporosis. Introd
Publikováno v:
Epilepsia. 32(3)
Summary: Five patients participated in a controlled discontinuation of phenytoin (PHT) and carbamazepine (CBZ) after a study in which all subjects had felbamate (FBM) added to both PHT and CBZ. Four subjects (three women and 1 man aged 23–36 years)
Publikováno v:
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy. 9:372-376
Felbamate is a novel antiepileptic drug currently undergoing clinical trials in the United States. Serum felbamate concentration data from a phase II safety and efficacy trial were analyzed using NONMEM. A one-compartment, open model with first-order
Publikováno v:
Epilepsia. 30(2)
Felbamate (FBM) is a novel antiepileptic drug (AED) undergoing clinical trials in the United States. During a double-blind, cross-over clinical trial, patients received concomitant phenytoin (PHT) and carbamazepine (CBZ). Dosages of PHT and CBZ were
Publikováno v:
Epilepsia. 28(6)
Summary: We evaluated the use of serum obtained from capillary blood specimens with the Seralyzer ARIS (AMES Division Miles Laboratories) assay for phenytoin (PHT) and phenobarbital (PB). The Ames Seralyzer method is capable of measuring PHT and PB c
Autor:
Robert D. Kriel, William E. Rosenfeld, Gary H. Carlson, Rory P. Remmel, Gregory B. Holmes, Nina M. Graves
Publikováno v:
Archives of neurology. 46(8)
• The absorption of valproic acid administered by rectal suppository was studied in six male volunteers. Valproic acid was incorporated into a synthetic lipid base in our pharmacy. Each subject received 500 mg of valproic acid by rectal suppository