Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Gregory B, Vanden Heuvel"'
Autor:
Tarak Srivastava, Trupti Joshi, Daniel P. Heruth, Mohammad H. Rezaiekhaligh, Robert E. Garola, Jianping Zhou, Varun C. Boinpelly, Mohammed Farhan Ali, Uri S. Alon, Madhulika Sharma, Gregory B. Vanden Heuvel, Pramod Mahajan, Lakshmi Priya, Yuexu Jiang, Ellen T. McCarthy, Virginia J. Savin, Ram Sharma, Mukut Sharma
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-19 (2021)
Abstract Systemic inflammation in pregnant obese women is associated with 1.5- to 2-fold increase in serum Interleukin-6 (IL-6) and newborns with lower kidney/body weight ratio but the role of IL-6 in increased susceptibility to chronic kidney (CKD)
Externí odkaz:
https://doaj.org/article/eba3b1af72d249d7980f6ba1dad3729b
Autor:
Rajni Vaid Puri, Sireesha Yerrathota, Trisha Home, Jessica Y. Idowu, V. Praveen Chakravarthi, Christopher J. Ward, Pravin C. Singhal, Gregory B. Vanden Heuvel, Timothy A. Fields, Madhulika Sharma
Publikováno v:
Disease Models & Mechanisms, Vol 12, Iss 12 (2019)
Notch pathway activation plays a central role in the pathogenesis of many glomerular diseases. We have previously shown that Notch4 expression was upregulated in various renal cells in human immunodeficiency virus (HIV)-associated nephropathy (HIVAN)
Externí odkaz:
https://doaj.org/article/a544e1427d1144e49e29e1d352cfedb9
Autor:
Heidi Griesmann, Sebastian Mühl, Jan Riedel, Katharina Theuerkorn, Bence Sipos, Irene Esposito, Gregory B. Vanden Heuvel, Patrick Michl
Publikováno v:
Cancers, Vol 13, Iss 10, p 2462 (2021)
The transcription factor CUX1 has been implicated in either tumor suppression or progression, depending on the cancer entity and the prevalent CUX1 isoform. Previously, we could show that CUX1 acts as an important mediator of tumor cell proliferation
Externí odkaz:
https://doaj.org/article/364c072590eb4c01bdd40a42e65326b2
Autor:
Gregory B. Vanden Heuvel, Sebastian Mühl, Patrick Michl, Irene Esposito, Jan Riedel, Katharina Theuerkorn, Bence Sipos, Heidi Griesmann
Publikováno v:
Cancers
Volume 13
Issue 10
Cancers, Vol 13, Iss 2462, p 2462 (2021)
Volume 13
Issue 10
Cancers, Vol 13, Iss 2462, p 2462 (2021)
The transcription factor CUX1 has been implicated in either tumor suppression or progression, depending on the cancer entity and the prevalent CUX1 isoform. Previously, we could show that CUX1 acts as an important mediator of tumor cell proliferation
Autor:
Daniel P. Heruth, Pramod B. Mahajan, Jianping Zhou, Mukut Sharma, Yuexu Jiang, Ram Sharma, Lakshmi Priya, Tarak Srivastava, Uri Alon, Trupti Joshi, Madhulika Sharma, Virginia J. Savin, Mohammed Farhan Ali, Gregory B. Vanden Heuvel, Robert E. Garola, Varun C. Boinpelly, Mohammad H. Rezaiekhaligh, Ellen T. McCarthy
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-19 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-19 (2021)
Systemic inflammation in pregnant obese women is associated with 1.5- to 2-fold increase in serum Interleukin-6 (IL-6) and newborns with lower kidney/body weight ratio but the role of IL-6 in increased susceptibility to chronic kidney (CKD) in adult
Autor:
Joshua C. Wright, Gregory B. Vanden Heuvel, Carol G. Carlton, Erica L. Andres, Alexandra M. Petrie, Safia Livingston, Binu Porath, Richard C. Baybutt, Anna E. Woo
Publikováno v:
American Journal of Physiology-Renal Physiology. 313:F1050-F1059
Autosomal dominant polycystic kidney disease (ADPKD) is one of the most common monogenic hereditary disorders in humans characterized by fluid-filled cysts, primarily in the kidneys. Cux1, a cell cycle regulatory gene highly expressed during kidney d
Autor:
Safia, Livingston, Carol, Carlton, Madhulika, Sharma, Donovan, Kearns, Richard, Baybutt, Gregory B, Vanden Heuvel
Publikováno v:
Gene: X. 2
Cux1 is a homeodomain protein involved in cell cycle regulation and kidney development. Cux1 represses the cyclin kinase inhibitor p27 during early kidney development, promoting cell proliferation in the nephrogenic zone. Promoter reporter analysis o
Autor:
Gregory B. Vanden Heuvel, Donovan Kearns, Richard Baybutt, Carol G. Carlton, Madhulika Sharma, Safia Livingston
Publikováno v:
Gene: X, Vol 2, Iss, Pp-(2019)
Cux1 is a homeodomain protein involved in cell cycle regulation and kidney development. Cux1 represses the cyclin kinase inhibitor p27 during early kidney development, promoting cell proliferation in the nephrogenic zone. Promoter reporter analysis o
Autor:
Monica Ellis, Gregory B. Vanden Heuvel, Emma Swayze, Conner Holthaus, Matthew Rumschlag, Aaron L. Zebolsky, Erik Larson PhD
Publikováno v:
The FASEB Journal. 32
Autor:
Gregory B. Vanden Heuvel, Binu M. Paul
Publikováno v:
Wiley Interdisciplinary Reviews: Developmental Biology. 3:465-487
Polycystic kidney disease (PKD) is a life-threatening genetic disorder characterized by the presence of fluid-filled cysts primarily in the kidneys. PKD can be inherited as autosomal recessive (ARPKD) or autosomal dominant (ADPKD) traits. Mutations i