Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Gregory Aubert"'
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Metabolic disorders such as obesity and type 2 diabetes (T2D) are increasingly prevalent worldwide, necessitating a deeper comprehension of their underlying mechanisms. However, translating findings from animal research to human patients remains chal
Externí odkaz:
https://doaj.org/article/cb1ab4da420945959ed89e255708a756
Autor:
Chaitanya K. Gavini, Nadia Elshareif, Gregory Aubert, Anand V. Germanwala, Nigel A. Calcutt, Virginie Mansuy-Aubert
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-14 (2022)
Abstract Background Peripheral neuropathy is a common and progressive disorder in the elderly that interferes with daily activities. It is of importance to find efficient treatments to treat or delay this age-related neurodegeneration. Silencing macr
Externí odkaz:
https://doaj.org/article/91929b57cb8741daa50a9e577295d26d
Autor:
Jomana Hatahet, Tyler M. Cook, Raiza R. Bonomo, Nadia Elshareif, Chaitanya K. Gavini, Chelsea R. White, Jason Jesse, Virginie Mansuy-Aubert, Gregory Aubert
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
More than 50% of patients with heart failure present with heart failure with preserved ejection fraction (HFpEF), and 80% of them are overweight or obese. In this study we developed an obesity associated pre-HFpEF mouse model and showed an improvemen
Externí odkaz:
https://doaj.org/article/2571248d5c164097bad987ebc3dcf512
Autor:
Sarah Talley, Raiza Bonomo, Chaitanya Gavini, Jomana Hatahet, Emily Gornick, Tyler Cook, Byeong Jae Chun, Pete Kekenes-Huskey, Gregory Aubert, Edward Campbell, Virginie Mansuy-Aubert
Publikováno v:
Disease Models & Mechanisms, Vol 15, Iss 6 (2022)
Obesity is an epidemic, and it is characterized by a state of low-grade systemic inflammation. A key component of inflammation is the activation of inflammasomes, multiprotein complexes that form in response to danger signals and that lead to activat
Externí odkaz:
https://doaj.org/article/d140b35e102c49a88ac585a76772fede
Autor:
Tyler M. Cook, Chaitanya K. Gavini, Jason Jesse, Gregory Aubert, Emily Gornick, Raiza Bonomo, Laurent Gautron, Brian T. Layden, Virginie Mansuy-Aubert
Publikováno v:
Molecular Metabolism, Vol 54, Iss , Pp 101350- (2021)
Objective: The vagus nerve provides a direct line of communication between the gut and the brain for proper regulation of energy balance and glucose homeostasis. Short-chain fatty acids (SCFAs) produced via gut microbiota fermentation of dietary fibe
Externí odkaz:
https://doaj.org/article/6021c23c9708486eb0d022d0dca9362c
Publikováno v:
Circulation. 144
Objective: We examined the effects of SGLT2 inhibition with Dapagliflozin (DAPA) on left ventricular ejection fraction (LVEF) and cardiomyocyte regeneration in mice after myocardial infraction (MI), a model for Heart Failure with reduced EF. Introduc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8dc695b9f5cb695982e98e814a6e6368
https://doi.org/10.1161/circ.144.suppl_1.10577
https://doi.org/10.1161/circ.144.suppl_1.10577
Autor:
Chaitanya K. Gavini, Nadia Elshareif, Gregory Aubert, Anand V. Germanwala, Nigel A. Calcutt, Virginie Mansuy-Aubert
Publikováno v:
Journal of neuroinflammation, vol 19, iss 1
Background Peripheral neuropathy is a common and progressive disorder in the elderly that interferes with daily activities. It is of importance to find efficient treatments to treat or delay this age-related neurodegeneration. Silencing macrophages b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5239bed1e6e85f6ba2067f1c5cb03a6e
https://pubmed.ncbi.nlm.nih.gov/35219337
https://pubmed.ncbi.nlm.nih.gov/35219337
Autor:
Anand V. Germanwala, Virginie Mansuy-Aubert, Gregory Aubert, Nadia Elshareif, Chaitanya K. Gavini, Nigel A. Calcutt
Peripheral neuropathy is a common and progressive disorder in the elderly that interferes with daily activities and increases the risk of injury. It is of importance to find efficient treatments to treat or delay this age-related neurodegeneration. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2c3ee5fa7690d13caca502b2ce93e1f
https://doi.org/10.1101/2021.09.22.461263
https://doi.org/10.1101/2021.09.22.461263
Autor:
Edward M. Campbell, Sarah Talley, Ben Chun, Chaitanya K. Gavini, Tyler Cook, Jomana Hatahet, Pete Kekenes-Huskey, Virginie Mansuy-Aubert, Raiza Bonomo, Gregory Aubert
Obesity is a current epidemic, affecting millions of individuals worldwide. Chronic obesity is characterized by a low-grade systemic inflammation besides not being a classic inflammatory disease. Many studies have tried to identify inflammatory insul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9b01f55b1642a07c2f7e80bc6e4e61e
https://doi.org/10.1101/2021.09.22.461384
https://doi.org/10.1101/2021.09.22.461384
Autor:
Sarah Talley, Raiza Bonomo, Chaitanya Gavini, Jomana Hatahet, Emily Gornick, Tyler Cook, Byeong Jae Chun, Pete Kekenes-Huskey, Gregory Aubert, Edward Campbell, Virginie Mansuy-Aubert
Publikováno v:
Disease modelsmechanisms. 15(6)
Obesity is an epidemic, and it is characterized by a state of low-grade systemic inflammation. A key component of inflammation is the activation of inflammasomes, multiprotein complexes that form in response to danger signals and that lead to activat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af93a59c59a7a7fb11ffabbba6b13ecb
https://pubmed.ncbi.nlm.nih.gov/35466363
https://pubmed.ncbi.nlm.nih.gov/35466363