Zobrazeno 1 - 10
of 206
pro vyhledávání: '"Gregory A. Reed"'
Autor:
Jonathan B. Wagner, Susan Abdel-Rahman, Geetha Raghuveer, Andrea Gaedigk, Erin C. Boone, Roger Gaedigk, Vincent S. Staggs, Gregory A. Reed, Na Zhang, J. Steven Leeder
Publikováno v:
Genes, Vol 15, Iss 1, p 99 (2024)
This clinical study examined the influence of SLCO1B1 c.521T>C (rs4149056) on plasma atorvastatin concentrations in pediatric hypercholesterolemia. The participants (8–21 years), including heterozygous (c.521T/C, n = 13), homozygous (c.521C/C, n =
Externí odkaz:
https://doaj.org/article/198ec000aedc4f7db50ff50e1be3f3f2
Fosciclopirox suppresses growth of high-grade urothelial cancer by targeting the γ-secretase complex
Autor:
Scott J. Weir, Prasad Dandawate, David Standing, Sangita Bhattacharyya, Prabhu Ramamoorthy, Parthasarathy Rangarajan, Robyn Wood, Amanda E. Brinker, Benjamin L. Woolbright, Mehmet Tanol, Tammy Ham, William McCulloch, Michael Dalton, Gregory A. Reed, Michael J. Baltezor, Roy A. Jensen, John A. Taylor, Shrikant Anant
Publikováno v:
Cell Death and Disease, Vol 12, Iss 6, Pp 1-20 (2021)
Abstract Ciclopirox (CPX) is an FDA-approved topical antifungal agent that has demonstrated preclinical anticancer activity in a number of solid and hematologic malignancies. Its clinical utility as an oral anticancer agent, however, is limited by po
Externí odkaz:
https://doaj.org/article/d4bbf6c8245447f1b012189797bdb6c4
Autor:
Gregory A. Reed, Gary J. Schiller, Suman Kambhampati, Martin S. Tallman, Dan Douer, Mark D. Minden, Karen W. Yee, Vikas Gupta, Joseph Brandwein, Yulia Jitkova, Marcela Gronda, Rose Hurren, Aisha Shamas‐Din, Andre C. Schuh, Aaron D. Schimmer
Publikováno v:
Cancer Medicine, Vol 5, Iss 11, Pp 3031-3040 (2016)
Abstract Acute myeloid leukemia (AML) cells meet the higher energy, metabolic, and signaling demands of the cell by increasing mitochondrial biogenesis and mitochondrial protein translation. Blocking mitochondrial protein synthesis through genetic an
Externí odkaz:
https://doaj.org/article/a10c49769cfe4648b838a6df9401d3ca
Publikováno v:
The Rural Educator, Vol 29, Iss 3 (2008)
As the accountability movement has gained momentum, policy makers and educators have strived to strike a difficult balance between the sometimes competing demands at the local, state, and federal levels. Efforts to improve accountability and teacher
Externí odkaz:
https://doaj.org/article/04438efe34b14deaaf1b0fa36c3ad34e
Autor:
Andrew K. Godwin, Qamar J. Khan, Bruce F. Kimler, Gregory A. Reed, Milind A. Phadnis, Stephen K. Williamson, Stephanie LaFaver, Jaimie Heldstab, Karissa Finke, Kelsey Schwensen, Rachel Yoder, Yen Y. Wang, Jilliann A. De Jong, Jecinta Scott, Sharon Lewis, Manana Elia, Shane R. Stecklein, Marc Hoffmann, Harsh B. Pathak, Ingrid Mayer, Lauren Nye, Anne O'Dea, Vandana G. Abramson, Priyanka Sharma
Supplementary text
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01abe936b9f7b7cf0046b9baf3d20f36
https://doi.org/10.1158/1078-0432.22481640.v1
https://doi.org/10.1158/1078-0432.22481640.v1
Autor:
Andrew K. Godwin, Qamar J. Khan, Bruce F. Kimler, Gregory A. Reed, Milind A. Phadnis, Stephen K. Williamson, Stephanie LaFaver, Jaimie Heldstab, Karissa Finke, Kelsey Schwensen, Rachel Yoder, Yen Y. Wang, Jilliann A. De Jong, Jecinta Scott, Sharon Lewis, Manana Elia, Shane R. Stecklein, Marc Hoffmann, Harsh B. Pathak, Ingrid Mayer, Lauren Nye, Anne O'Dea, Vandana G. Abramson, Priyanka Sharma
Purpose:PIK3CA mutations are common in breast cancer and promote tumor progression and treatment resistance. We conducted a phase I/II trial of alpelisib (α-specific PI3K inhibitor) plus nab-paclitaxel in patients with HER2-negative metastatic breas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5663202857f8528f331d69cee18ca0d
https://doi.org/10.1158/1078-0432.c.6530748
https://doi.org/10.1158/1078-0432.c.6530748
Autor:
Andrew K. Godwin, Qamar J. Khan, Bruce F. Kimler, Gregory A. Reed, Milind A. Phadnis, Stephen K. Williamson, Stephanie LaFaver, Jaimie Heldstab, Karissa Finke, Kelsey Schwensen, Rachel Yoder, Yen Y. Wang, Jilliann A. De Jong, Jecinta Scott, Sharon Lewis, Manana Elia, Shane R. Stecklein, Marc Hoffmann, Harsh B. Pathak, Ingrid Mayer, Lauren Nye, Anne O'Dea, Vandana G. Abramson, Priyanka Sharma
Kaplan-Meier estimates of progression-free survival by baseline metabolic status
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76c4072df0719d7d14184896a108f226
https://doi.org/10.1158/1078-0432.22481646
https://doi.org/10.1158/1078-0432.22481646
Autor:
Andrew K. Godwin, Qamar J. Khan, Bruce F. Kimler, Gregory A. Reed, Milind A. Phadnis, Stephen K. Williamson, Stephanie LaFaver, Jaimie Heldstab, Karissa Finke, Kelsey Schwensen, Rachel Yoder, Yen Y. Wang, Jilliann A. De Jong, Jecinta Scott, Sharon Lewis, Manana Elia, Shane R. Stecklein, Marc Hoffmann, Harsh B. Pathak, Ingrid Mayer, Lauren Nye, Anne O'Dea, Vandana G. Abramson, Priyanka Sharma
Gene expression signatures by PIK3CA mutation status
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2222390849891e00adf02280b04f90c4
https://doi.org/10.1158/1078-0432.22481643
https://doi.org/10.1158/1078-0432.22481643
Autor:
Andrew K. Godwin, Qamar J. Khan, Bruce F. Kimler, Gregory A. Reed, Milind A. Phadnis, Stephen K. Williamson, Stephanie LaFaver, Jaimie Heldstab, Karissa Finke, Kelsey Schwensen, Rachel Yoder, Yen Y. Wang, Jilliann A. De Jong, Jecinta Scott, Sharon Lewis, Manana Elia, Shane R. Stecklein, Marc Hoffmann, Harsh B. Pathak, Ingrid Mayer, Lauren Nye, Anne O'Dea, Vandana G. Abramson, Priyanka Sharma
Kaplan-Meier estimates of overall survival
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c428ad31044731a724dd38b24c940b6b
https://doi.org/10.1158/1078-0432.22481649.v1
https://doi.org/10.1158/1078-0432.22481649.v1
Fosciclopirox suppresses growth of high-grade urothelial cancer by targeting the γ-secretase complex
Autor:
Mehmet Tanol, Scott Weir, William McCulloch, Prasad Dandawate, Shrikant Anant, Parthasarathy Rangarajan, Roy A. Jensen, David Standing, Prabhu Ramamoorthy, Michael Baltezor, Amanda E. Brinker, Michael Dalton, Robyn Wood, Gregory A. Reed, Tammy Ham, Benjamin L. Woolbright, John A. Taylor, Sangita Bhattacharyya
Publikováno v:
Cell Death and Disease, Vol 12, Iss 6, Pp 1-20 (2021)
Cell Death & Disease
Cell Death & Disease
Ciclopirox (CPX) is an FDA-approved topical antifungal agent that has demonstrated preclinical anticancer activity in a number of solid and hematologic malignancies. Its clinical utility as an oral anticancer agent, however, is limited by poor oral b