Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Gregory A. Gunawan"'
Autor:
GuangRong Peh, Gregory A. Gunawan, Terence Tay, Elaine Tiong, Lee Ling Tan, Shimin Jiang, Yi Ling Goh, Suming Ye, Joel Wong, Christopher J. Brown, Huimin Zhao, Ee Lui Ang, Fong Tian Wong, Yee Hwee Lim
Publikováno v:
Biomolecules, Vol 13, Iss 7, p 1081 (2023)
RadH is one of the flavin-dependent halogenases that has previously exhibited promising catalytic activity towards hydroxycoumarin, hydroxyisoquinoline, and phenolic derivatives. Here, we evaluated new functional homologs of RadH and expanded its spe
Externí odkaz:
https://doaj.org/article/685de206982d4cb3b414fc26b0efd08c
Autor:
Kevin Timothy, Fridianto, Gregory Adrian, Gunawan, Kiel, Hards, Jickky Palmae, Sarathy, Gregory M, Cook, Thomas, Dick, Mei-Lin, Go, Yulin, Lam
Publikováno v:
RSC medicinal chemistry. 13(12)
Due to its central role in energy generation and bacterial viability, mycobacterial bioenergetics is an attractive therapeutic target for anti-tuberculosis drug discovery. Building upon our work on antimycobacterial dioxonaphthoimidazoliums that were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dc0a601c84487642065746f261a807f3
https://pubmed.ncbi.nlm.nih.gov/36545436
https://pubmed.ncbi.nlm.nih.gov/36545436
Autor:
Ryosuke Sugiyama, Angelica Faith L. Suarez, Yohei Morishita, Thi Quynh Ngoc Nguyen, Yi Wei Tooh, Muhammad Nur Hadi Bin Roslan, Justin Lo Choy, Qi Su, Wei Yang Goh, Gregory Adrian Gunawan, Fong Tian Wong, Brandon I. Morinaka
Publikováno v:
Journal of the American Chemical Society. 144(26)
Peptide-derived cyclophanes inhabit a unique niche in the chemical space of macrocyclic peptides with several examples of pharmaceutical importance. Although both synthetic and biocatalytic methods are available for constructing these macrocycles, ve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f4624a2b9c2bdd18d14d158c884d0c8
https://pubmed.ncbi.nlm.nih.gov/35729768
https://pubmed.ncbi.nlm.nih.gov/35729768
Autor:
Kevin Timothy Fridianto, Gregory Adrian Gunawan, Kiel Hards, Jickky Palmae Sarathy, Gregory M. Cook, Thomas Dick, Mei-Lin Go, Yulin Lam
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e0426625cea69551652718dccc4ec44
https://doi.org/10.2139/ssrn.4085430
https://doi.org/10.2139/ssrn.4085430
Autor:
Gregory A. Gunawan, Mariola Gimła, Michael G. Gardiner, Anna Herman-Antosiewicz, Tristan A. Reekie
Publikováno v:
Bioorganic & Medicinal Chemistry. 79:117157
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8c0bccbe7fd9d0ced74d01c680057da
https://doi.org/10.1016/j.bmc.2023.117157
https://doi.org/10.1016/j.bmc.2023.117157
Autor:
Samuel Agyei Nyantakyi, Ming Li, Mei-Lin Go, Gregory Adrian Gunawan, Yu Jia Tan, Thomas Dick, Yulin Lam
Publikováno v:
ACS Med Chem Lett
[Image: see text] Indolecarboxamides are potent but poorly soluble mycobactericidal agents. Here we found that modifying the incipient scaffold by amide–amine substitution and replacing the indole ring with benzothiophene or benzoselenophene led to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f0e1122efb2875b690b4d4ebf4276b8
https://pubmed.ncbi.nlm.nih.gov/34055215
https://pubmed.ncbi.nlm.nih.gov/34055215