Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Gregory A. Fishbein"'
Autor:
Jade Jaffar, Mae Wong, Gregory A. Fishbein, Monther Alhamdoosh, Laura McMillan, Cristina Gamell-Fulla, Milica Ng, Nick Wilson, Karen Symons, Ian Glaspole, Glen Westall
Publikováno v:
ERJ Open Research, Vol 8, Iss 4 (2022)
Introduction Idiopathic pulmonary fibrosis (IPF) is a progressively fibrotic lung condition with poor prognosis. Matrix metalloproteinase-7 (MMP7) is a protein secreted by epithelial cells in IPF lungs. It is not known if MMP7 expression correlates w
Externí odkaz:
https://doaj.org/article/100231e77cc2445ab07eb39a4bc2833d
Autor:
Reiri Sono, Tania M. Larrinaga, Alden Huang, Frank Makhlouf, Xuedong Kang, Jonathan Su, Ryan Lau, Valerie A. Arboleda, Reshma Biniwale, Gregory A. Fishbein, Negar Khanlou, Ming-Sing Si, Gary M. Satou, Nancy Halnon, UCLA Congenital Heart Defects-BioCore Faculty, Glen S. Van Arsdell, Carol C. Gregorio, Stanly Nelson, Marlin Touma
Publikováno v:
Cells, Vol 12, Iss 11, p 1455 (2023)
As an essential component of the sarcomere, actin thin filament stems from the Z-disk extend toward the middle of the sarcomere and overlaps with myosin thick filaments. Elongation of the cardiac thin filament is essential for normal sarcomere matura
Externí odkaz:
https://doaj.org/article/1549951580934b4d81d7ef112d28c224
Autor:
Jamie O. Yang, Hapet Shaybekyan, Yan Zhao, Xuedong Kang, Gregory A. Fishbein, Negar Khanlou, Juan C. Alejos, Nancy Halnon, Gary Satou, Reshma Biniwale, Hane Lee, Glen Van Arsdell, Stanley F. Nelson, Marlin Touma, the UCLA Clinical Genomics Center, the UCLA Congenital Heart Defects-BioCore Faculty
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2022)
We report a case of hypertrophic cardiomyopathy and lactic acidosis in a 3-year-old female. Cardiac and skeletal muscles biopsies exhibited mitochondrial hyperplasia with decreased complex IV activity. Whole exome sequencing identified compound heter
Externí odkaz:
https://doaj.org/article/3249993441454cc5a561ada6b4c8bd1b
Autor:
Zekun Feng, MD, PharmD, Daniel Philipson, MD, Jamar P. Uzzell, MD, Ashley Stein-Merlob, MD, Eric H. Yang, MD, Holly R. Middlekauff, MD, Ryan P. Lau, MD, Gregory A. Fishbein, MD, Jason S. Bradfield, MD, Olujimi A. Ajijola, MD, PhD
Publikováno v:
JACC: Case Reports, Vol 2, Iss 7, Pp 1049-1055 (2020)
The presentation of a cardiac hamartoma, an exceedingly rare and histologically benign cardiac tumor, can be variable. We describe a case of refractory ventricular tachycardia in a patient with a cardiac mass failing multiple pharmacologic and proced
Externí odkaz:
https://doaj.org/article/c86e9626f0a74f58884230b1b818fe4e
Autor:
Amanda Chang, Gabriel Stolin, Judith Fan, Boris R. Larreta, Gregory A. Fishbein, William Dean Wallace, Arnold S. Baas, Daniel Cruz, Jessica Wang
Publikováno v:
ESC Heart Failure, Vol 6, Iss 6, Pp 1326-1330 (2019)
Abstract Hydroxychloroquine (HCQ) is a well‐established and effective immunomodulatory therapy for systemic lupus erythematosus and other autoimmune diseases. While retinal toxicity is a well‐recognized complication, cardiotoxicity is lesser know
Externí odkaz:
https://doaj.org/article/7e4fdfa97ea54bafa38cf0a032b6d7c2
Autor:
Timothy J. Young, Ramin Salehi-Rad, Reza Ronaghi, Jane Yanagawa, Puja Shahrouki, Bianca E. Villegas, Brian Cone, Gregory A. Fishbein, William D. Wallace, Fereidoun Abtin, Igor Barjaktarevic
Publikováno v:
Medical Sciences, Vol 10, Iss 3, p 34 (2022)
Lung adenocarcinoma with lepidic growth pattern (LPA) is characterized by tumor cell proliferation along intact alveolar walls, and further classified as adenocarcinoma in situ (AIS), minimally invasive adenocarcinoma (MIA) and invasive lepidic predo
Externí odkaz:
https://doaj.org/article/6621a124e6054b8eb2553fa962940d53
Autor:
Shen Li, Feiyang Ma, Tomohiro Yokota, Gustavo Garcia Jr., Amelia Palermo, Yijie Wang, Colin Farrell, Yu-Chen Wang, Rimao Wu, Zhiqiang Zhou, Calvin Pan, Marco Morselli, Michael A. Teitell, Sergey Ryazantsev, Gregory A. Fishbein, Johanna ten Hoeve, Valerie A. Arboleda, Joshua Bloom, Barbara Dillon, Matteo Pellegrini, Aldons J. Lusis, Thomas G. Graeber, Vaithilingaraja Arumugaswami, Arjun Deb
Publikováno v:
JCI Insight, Vol 6, Iss 2 (2021)
Extrapulmonary manifestations of COVID-19 are associated with a much higher mortality rate than pulmonary manifestations. However, little is known about the pathogenesis of systemic complications of COVID-19. Here, we create a murine model of SARS-Co
Externí odkaz:
https://doaj.org/article/5eccd2b0db0941ecae1137cd886d2357
Publikováno v:
BMC Medical Genetics, Vol 19, Iss 1, Pp 1-4 (2018)
Abstract Background The Protein Kinase AMP-Activated Non-Catalytic Subunit Gamma 2 (PRKAG2) cardiac syndrome is characterized by glycogen accumulation in the cardiac tissue. The disease presents clinically with hypertrophic cardiomyopathy (HCM), and
Externí odkaz:
https://doaj.org/article/4f273a7a55e94a24b0afb9b519679d1d
Autor:
Paige M. K. Larkin, Ashrit Multani, Omer E. Beaird, Ayrton J. Dayo, Gregory A. Fishbein, Shangxin Yang
Publikováno v:
Journal of Fungi, Vol 6, Iss 3, p 106 (2020)
Chronic pulmonary aspergillosis (CPA) refers to a spectrum of Aspergillus-mediated disease that is associated with high morbidity and mortality, with its true prevalence vastly underestimated. The diagnosis of CPA includes characteristic radiographic
Externí odkaz:
https://doaj.org/article/8b68c67b1af844d69622710b7ee67e1a
Autor:
Michael Y. Shino, Jamie L. Todd, Megan L. Neely, Jerry Kirchner, Courtney W. Frankel, Laurie D. Snyder, Elizabeth N. Pavlisko, Gregory A. Fishbein, Joanna M. Schaenman, Kristen Mason, Karen Kesler, Tereza Martinu, Lianne G. Singer, Wayne Tsuang, Marie Budev, Pali D. Shah, John M. Reynolds, Nikki Williams, Mark A. Robien, Scott M. Palmer, S. Sam Weigt, John A. Belperio
Publikováno v:
American Journal of Transplantation. 22:2169-2179
Histopathologic lung allograft injuries are putative harbingers for chronic lung allograft dysfunction (CLAD). However, the mechanisms responsible are not well understood. CXCL9 and CXCL10 are potent chemoattractants of mononuclear cells and potentia