Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Gregory A. Fendley"'
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0238754 (2020)
Heme biosynthesis occurs through a series of reactions that take place within the cytoplasm and mitochondria, so intermediates need to move across these cellular compartments. However, the specific membrane transport mechanisms involved in the proces
Externí odkaz:
https://doaj.org/article/fac62f93284d4a44a55b7d806c3acad9
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0238754 (2020)
PLoS ONE
PLoS ONE
Heme biosynthesis occurs through a series of reactions that take place within the cytoplasm and mitochondria, thus intermediates need to move across these cellular compartments. However, the specific membrane transport mechanisms involved in the proc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cf133fcf05edddffea745127bb113f1
https://doi.org/10.1101/2020.08.25.266007
https://doi.org/10.1101/2020.08.25.266007
Autor:
Anukriti Singh, Ina L. Urbatsch, Gregory A. Fendley, Maria E. Zoghbi, Leo Mok, Guillermo A. Altenberg, Douglas J. Swartz
Publikováno v:
The Journal of biological chemistry, vol 292, iss 50
P-glycoprotein (Pgp) is an efflux pump important in multidrug resistance of cancer cells and in determining drug pharmacokinetics. Pgp is a prototype ATP-binding cassette transporter with two nucleotide-binding domains (NBDs) that bind and hydrolyze
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9cc751d6378f16f80e18e39ca84b80b
https://doi.org/10.1074/jbc.m117.814186
https://doi.org/10.1074/jbc.m117.814186
Publikováno v:
Protein Expr Purif
Membrane proteins play important roles in health and disease. Despite their importance, the study of membrane proteins has been significantly limited by the difficulties inherent to their successful expression, purification, and stabilization once th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db458dad292ab6bc64df013c94472bc0
https://doi.org/10.1016/j.pep.2020.105778
https://doi.org/10.1016/j.pep.2020.105778
Autor:
Roger Bryan Sutton, Maria E. Zoghbi, Guillermo A. Altenberg, Gregory A. Fendley, Ina L. Urbatsch
Publikováno v:
Biochemical and Biophysical Research Communications. 480:268-272
ATP-binding cassette proteins are ubiquitously present throughout all known genomes. Their basic functional unit possesses two transmembrane domains and two nucleotide-binding domains. The nucleotide-binding domains are responsible for ATP binding an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec5617624f61a13c0f715da60da7ad9a
https://doi.org/10.1016/j.bbrc.2016.10.046
https://doi.org/10.1016/j.bbrc.2016.10.046