Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Gregory A Raciti"'
Autor:
Antonella Desiderio, Monica Pastorino, Michele Campitelli, Michele Longo, Claudia Miele, Raffaele Napoli, Francesco Beguinot, Gregory Alexander Raciti
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-17 (2024)
Abstract Background Cardiovascular diseases (CVD) affect over half a billion people worldwide and are the leading cause of global deaths. In particular, due to population aging and worldwide spreading of risk factors, the prevalence of heart failure
Externí odkaz:
https://doaj.org/article/22874d2adca3478a96d405b07b92ac66
Autor:
Angela Cassese, Gregory A Raciti, Francesca Fiory, Cecilia Nigro, Luca Ulianich, Ilenia Castanò, Vittoria D'Esposito, Daniela Terracciano, Lucio Pastore, Pietro Formisano, Francesco Beguinot, Claudia Miele
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60555 (2013)
Over-expression of phosphoprotein enriched in diabetes/phosphoprotein enriched in astrocytes (PED/PEA-15) causes insulin resistance by interacting with the D4 domain of phospholipase D1 (PLD1). Indeed, the disruption of this association restores insu
Externí odkaz:
https://doaj.org/article/2b1b4ecaf1d24ddeaf20405c6094b3dc
Autor:
Xiu-Fen Liu, Tapan K Bera, Charissa Kahue, Thelma Escobar, Zhaoliang Fei, Gregory A Raciti, Ira Pastan
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e38130 (2012)
Partial inactivation of the Ankyrin repeat domain 26 (Ankrd26) gene causes obesity and diabetes in mice and increases spontaneous and induced adipogenesis in mouse embryonic fibroblasts. However, it is not yet known how the Ankrd26 protein carries ou
Externí odkaz:
https://doaj.org/article/ffcc9eecd47946ef964e100d92a798e3
Autor:
Michele Longo, Federica Zatterale, Rosa Spinelli, Jamal Naderi, Luca Parrillo, Pasqualina Florese, Cecilia Nigro, Alessia Leone, Augusta Moccia, Antonella Desiderio, Gregory A. Raciti, Claudia Miele, Ulf Smith, Francesco Beguinot
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-24 (2023)
Abstract Background First-degree relatives of type 2 diabetics (FDR) exhibit a high risk of developing type 2 diabetes (T2D) and feature subcutaneous adipocyte hypertrophy, independent of obesity. In FDR, adipose cell abnormalities contribute to earl
Externí odkaz:
https://doaj.org/article/67d0a5fc91c74ab8832d99e8826746b5
Autor:
Luca Parrillo, Rosa Spinelli, Michele Longo, Federica Zatterale, Gianluca Santamaria, Alessia Leone, Michele Campitelli, Gregory Alexander Raciti, Francesco Beguinot
Publikováno v:
Cells, Vol 12, Iss 16, p 2090 (2023)
The transcription factor HOXA5, from the HOX gene family, has long been studied due to its critical role in physiological activities in normal cells, such as organ development and body patterning, and pathological activities in cancer cells. Nonethel
Externí odkaz:
https://doaj.org/article/862612a4bea44cc08d945e65e8d35417
Autor:
Alessia Leone, Antonella Nicolò, Immacolata Prevenzano, Federica Zatterale, Michele Longo, Antonella Desiderio, Rosa Spinelli, Michele Campitelli, Domenico Conza, Gregory Alexander Raciti, Francesco Beguinot, Cecilia Nigro, Claudia Miele
Publikováno v:
Cells, Vol 12, Iss 13, p 1741 (2023)
Adipose-derived stem cells (ADSCs) play a crucial role in angiogenesis and repair of damaged tissues. However, in pathological conditions including diabetes, ADSC function is compromised. This work aims at evaluating the effect of Methylglyoxal (MGO)
Externí odkaz:
https://doaj.org/article/ae86b98c3888430b893c0a56643f7c45
Autor:
Federica Zatterale, Gregory Alexander Raciti, Immacolata Prevenzano, Alessia Leone, Michele Campitelli, Veronica De Rosa, Francesco Beguinot, Luca Parrillo
Publikováno v:
Biomolecules, Vol 12, Iss 7, p 982 (2022)
For the past several decades, the prevalence of obesity and type 2 diabetes (T2D) has continued to rise on a global level. The risk contributing to this pandemic implicates both genetic and environmental factors, which are functionally integrated by
Externí odkaz:
https://doaj.org/article/9edcf110c91d47cc98ebc910c78e8b3b
Autor:
Miele, Alessia Leone, Antonella Nicolò, Immacolata Prevenzano, Federica Zatterale, Michele Longo, Antonella Desiderio, Rosa Spinelli, Michele Campitelli, Domenico Conza, Gregory Alexander Raciti, Francesco Beguinot, Cecilia Nigro, Claudia
Publikováno v:
Cells; Volume 12; Issue 13; Pages: 1741
Adipose-derived stem cells (ADSCs) play a crucial role in angiogenesis and repair of damaged tissues. However, in pathological conditions including diabetes, ADSC function is compromised. This work aims at evaluating the effect of Methylglyoxal (MGO)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::033458b559a142205edcbc9399919853
Autor:
Rosa Spinelli, Pasqualina Florese, Luca Parrillo, Federica Zatterale, Michele Longo, Vittoria D’Esposito, Antonella Desiderio, Annika Nerstedt, Birgit Gustafson, Pietro Formisano, Claudia Miele, Gregory Alexander Raciti, Raffaele Napoli, Ulf Smith, Francesco Beguinot
Publikováno v:
Aging Cell. 21
Senescence of adipose precursor cells (APC) impairs adipogenesis, contributes to the age-related subcutaneous adipose tissue (SAT) dysfunction, and increases risk of type 2 diabetes (T2D). First-degree relatives of T2D individuals (FDR) feature restr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::184466bf7670c38fe470dee09c5319f5
https://doi.org/10.1111/acel.13557
https://doi.org/10.1111/acel.13557
Autor:
Luca, Parrillo, Rosa, Spinelli, Mattia, Costanzo, Pasqualina, Florese, Serena, Cabaro, Antonella, Desiderio, Immacolata, Prevenzano, Gregory Alexander, Raciti, Ulf, Smith, Claudia, Miele, Pietro, Formisano, Raffaele, Napoli, Francesco, Beguinot
Publikováno v:
Cells. 11(4)
Along with insulin resistance and increased risk of type 2 diabetes (T2D), lean first-degree relatives of T2D subjects (FDR) feature impaired adipogenesis in subcutaneous adipose tissue (SAT) and subcutaneous adipocyte hypertrophy well before diabete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::732ec628d7ad4eaddcc9372b39ce80a6
https://pubmed.ncbi.nlm.nih.gov/35203377
https://pubmed.ncbi.nlm.nih.gov/35203377