Zobrazeno 1 - 10 of 130 pro vyhledávání: '"Gregory A Cary"'
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Akademický článek
Genetic and multi‐omic risk assessment of Alzheimer's disease implicates core associated biological domains
Autor: Gregory A. Cary, Jesse C. Wiley, Jake Gockley, Stephen Keegan, Sai Sruthi Amirtha Ganesh, Laura Heath, Robert R. Butler III, Lara M. Mangravite, Benjamin A. Logsdon, Frank M. Longo, Allan Levey, Anna K. Greenwood, Gregory W. Carter
Publikováno v: Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 10, Iss 2, Pp n/a-n/a (2024)
Abstract INTRODUCTION Alzheimer's disease (AD) is the predominant dementia globally, with heterogeneous presentation and penetrance of clinical symptoms, variable presence of mixed pathologies, potential disease subtypes, and numerous associated endo
Externí odkaz: https://doaj.org/article/87b26c23678e4f5998805f9ff4358f67
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2
Akademický článek
Characterization of covalent inhibitors that disrupt the interaction between the tandem SH2 domains of SYK and FCER1G phospho-ITAM.
Autor: Frances M Bashore, Vittorio L Katis, Yuhong Du, Arunima Sikdar, Dongxue Wang, William J Bradshaw, Karolina A Rygiel, Tina M Leisner, Rod Chalk, Swati Mishra, C Andrew Williams, Opher Gileadi, Paul E Brennan, Jesse C Wiley, Jake Gockley, Gregory A Cary, Gregory W Carter, Jessica E Young, Kenneth H Pearce, Haian Fu, Emory-Sage-SGC TREAT-AD Center, Alison D Axtman
Publikováno v: PLoS ONE, Vol 19, Iss 2, p e0293548 (2024)
RNA sequencing and genetic data support spleen tyrosine kinase (SYK) and high affinity immunoglobulin epsilon receptor subunit gamma (FCER1G) as putative targets to be modulated for Alzheimer's disease (AD) therapy. FCER1G is a component of Fc recept
Externí odkaz: https://doaj.org/article/a694cd69ff044329bed258122700d8e8
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3
Akademický článek
Systematic comparison of sea urchin and sea star developmental gene regulatory networks explains how novelty is incorporated in early development
Autor: Gregory A. Cary, Brenna S. McCauley, Olga Zueva, Joseph Pattinato, William Longabaugh, Veronica F. Hinman
Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
It is unclear how a gene regulatory network (GRN) incorporates novelty whilst still maintaining overall stability. Here, the authors provide a comprehensive GRN for endomesoderm specification in the sea star from zygote stage to gastrulation, showing
Externí odkaz: https://doaj.org/article/f9896b6049de47a5a5a06fb0398c126b
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4
Akademický článek
Analysis of sea star larval regeneration reveals conserved processes of whole-body regeneration across the metazoa
Autor: Gregory A. Cary, Andrew Wolff, Olga Zueva, Joseph Pattinato, Veronica F. Hinman
Publikováno v: BMC Biology, Vol 17, Iss 1, Pp 1-19 (2019)
Abstract Background Metazoan lineages exhibit a wide range of regenerative capabilities that vary among developmental stage and tissue type. The most robust regenerative abilities are apparent in the phyla Cnidaria, Platyhelminthes, and Echinodermata
Externí odkaz: https://doaj.org/article/e063eb7fd856496685bab7c87f96b864
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8
Analysis of sea star larval regeneration reveals conserved processes of whole-body regeneration across the metazoa
Autor: Veronica F. Hinman, Gregory A. Cary, Joseph Pattinato, Andrew Wolff, Olga R. Zueva
Publikováno v: BMC Biology, Vol 17, Iss 1, Pp 1-19 (2019)
BMC Biology
BackgroundMetazoan lineages exhibit a wide range of regenerative capabilities that vary among developmental stage and tissue type. The most robust regenerative abilities are apparent in the phyla Cnidaria, Platyhelminthes, and Echinodermata, whose me
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d272d8d3b24a2b3c2150ce4154c741a
http://link.springer.com/article/10.1186/s12915-019-0633-9
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9
Akademický článek
Unidirectional P-body transport during the yeast cell cycle.
Autor: Cecilia Garmendia-Torres, Alexander Skupin, Sean A Michael, Pekka Ruusuvuori, Nathan J Kuwada, Didier Falconnet, Gregory A Cary, Carl Hansen, Paul A Wiggins, Aimée M Dudley
Publikováno v: PLoS ONE, Vol 9, Iss 6, p e99428 (2014)
P-bodies belong to a large family of RNA granules that are associated with post-transcriptional gene regulation, conserved from yeast to mammals, and influence biological processes ranging from germ cell development to neuronal plasticity. RNA granul
Externí odkaz: https://doaj.org/article/2ac7b0475acb43e3983bad4b8ced7e11
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10
3D genomics across the tree of life reveals condensin II as a determinant of architecture type
Autor: Judy St. Leger, Bram van den Broek, Ahmed M.O. Elbatsh, Leonid L. Moroz, Evin Hildebrandt, Namita Mitra, Parwinder Kaur, Roger D. Kornberg, Federica Di Palma, Nils Stein, Weijie Yao, Theresa L.U. Burnham, Christopher J. Knight, Suhas S.P. Rao, Kazuhiro Maeshima, Asha S. Multani, Veronica F. Hinman, Aditya N. Mhaskar, José N. Onuchic, David Weisz, Sen Pathak, René H. Medema, Kevin A. Hovel, Arina D. Omer, Alexandria Mena, Andrea B. Kohn, Andrew J. Beel, Liesl Nel-Themaat, Benjamin D. Rowland, José Luis Gómez-Skarmeta, Bas van Steensel, Maria Cristina Gambetta, Claire Hoencamp, Christopher Lui, Roy G.H.P. van Heesbeen, Emma K. Farley, Olga Dudchenko, Michele Di Pierro, Neil D. Young, Meng C. Wang, Kerstin Lindblad-Toh, Pierre Jean Mattei, Tom van Schaik, Melanie Pham, Ruqayya Khan, Fabian Lim, Wesley C. Warren, Vinícius G. Contessoto, Richard R. Behringer, Hans H. Cheng, Alexander Haddad, Gregory A. Cary, Daniel Chauss, Zane Colaric, Hans Teunissen, Ayse Sena Mutlu, Zhenzhen Yang, Ángela Sedeño Cacciatore, Elzo de Wit, Sumitabha Brahmachari, Erez Lieberman Aiden, Karen Holcroft, Jonne A. Raaijmakers, Brian Glenn St Hilaire
Publikováno v: Science
Science (New York, N.Y.), vol 372, iss 6545
Digital.CSIC. Repositorio Institucional del CSIC
instname
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
We investigated genome folding across the eukaryotic tree of life. We find two types of three-dimensional(3D) genome architectures at the chromosome scale. Each type appears and disappears repeatedlyduring eukaryotic evolution. The type of genome arc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7def7f95c1bea4f8af665cc0bb48a7cb
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