Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Gregory A Bohach"'
Autor:
Gillian J Wilson, Keun Seok Seo, Robyn A Cartwright, Timothy Connelley, Olivia N Chuang-Smith, Joseph A Merriman, Caitriona M Guinane, Joo Youn Park, Gregory A Bohach, Patrick M Schlievert, W Ivan Morrison, J Ross Fitzgerald
Publikováno v:
PLoS Pathogens, Vol 7, Iss 10, p e1002271 (2011)
Bacterial superantigens (SAg) stimulate T-cell hyper-activation resulting in immune modulation and severe systemic illnesses such as Staphylococcus aureus toxic shock syndrome. However, all known S. aureus SAgs are encoded by mobile genetic elements
Externí odkaz:
https://doaj.org/article/bd56f7a9b7594e6393143c69934225eb
Autor:
Justin L Spinner, Keun Seok Seo, Jason L O'Loughlin, Jennifer A Cundiff, Scott A Minnich, Gregory A Bohach, Scott D Kobayashi
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9279 (2010)
BackgroundThe human innate immune system relies on the coordinated activity of macrophages and polymorphonuclear leukocytes (neutrophils or PMNs) for defense against bacterial pathogens. Yersinia spp. subvert the innate immune response to cause disea
Externí odkaz:
https://doaj.org/article/3f5147da69a249e9a95227c3368a268c
Publikováno v:
Journal of Bacteriology
Maintenance of phospholipid (PL) and lipopoly- or lipooligo-saccharide (LPS or LOS) asymmetry in the outer membrane (OM) of Gram-negative bacteria is essential but poorly understood. The Yersinia pestis OM Ail protein was required to maintain lipid h
Autor:
Xianglu Li, William G. Fusco, Keun S. Seo, Kenneth W. Bayles, Erin E. Mosley, Mark A. McGuire, Gregory A. Bohach
Publikováno v:
International Journal of Microbiology, Vol 2009 (2009)
HEp-2 cell monolayers were cocultured with intracellular Staphylococcus aureus, and changes in gene expression were profiled using DNA microarrays. Intracellular S. aureus affected genes involved in cellular stress responses, signal transduction, inf
Externí odkaz:
https://doaj.org/article/3a5694d7ae3846b7bc1592ad2193bdbb
Autor:
Gregory A. Bohach, Andrzej Paszczynski, Scott A. Minnich, Carolyn J. Hovde, Allan Caplan, Anna M. Kolodziejek
Publikováno v:
Applied and Environmental Microbiology. 79:4509-4514
Yersinia pestis grown with physiologic glucose increased cell autoaggregation and deposition of extracellular material, including membrane vesicles. Membranes were characterized, and glucose had significant effects on protein, lipid, and carbohydrate
Autor:
Gregory A. Bohach, Jennifer Maratea, Darla R. Ewalt, Richard A. French, Claudia F. Deobald, David J. St. Aubin, Patrick M. Schlievert, Caroline E. C. Goertz, Sylvain De Guise, Daniel F. Cowan, Lynn Hinckley, Salvatore Frasca, Sheila M. Karst, J. Lawrence Dunn, John D. Buck
Publikováno v:
Journal of Veterinary Diagnostic Investigation. 23:845-851
A previously beach-stranded, juvenile, male, bottlenose dolphin ( Tursiops truncatus) was diagnosed with vertebral osteomyelitis of unknown etiology. Antemortem serological testing suggested past or current Brucella sp. infection; however, this could
Autor:
William M. Sischo, Fred R. Rurangirwa, Yong Ho Park, Joo Youn Park, Keun Seok Seo, Gregory A. Bohach, Mark A. McGuire, Lawrence K. Fox
Publikováno v:
Veterinary Microbiology. 147(1-2):142-148
Coagulase-negative staphylococci (CNS) are the most frequently isolated pathogens from cows with intramammary infection (IMI). Although API STAPH ID 20, a commercially available identification system, and PCR-restriction fragment length polymorphism
Autor:
Gregory A. Bohach, Carolyn J. Hovde, Scott A. Minnich, Andrzej J. Wojtowicz, Anna M. Kolodziejek, Harold N. Rohde, Darren R. Schnider
Publikováno v:
Infection and Immunity. 78:5233-5243
Yersinia pestis , the causative agent of plague, is one of the most virulent microorganisms known. The outer membrane protein X (OmpX) in Y. pestis KIM is required for efficient bacterial adherence to and internalization by cultured HEp-2 cells and c
Publikováno v:
Veterinary Immunology and Immunopathology. 128(1-3):30-36
The role of regulatory T cells (Tregs) is well documented in immune homeostasis and protection against autoimmune disease. Forkhead box protein 3 (FOXP3) has been shown to be essential for the development and function of T(reg). Due to the lack of to
Autor:
Lawrence K. Fox, Joo Youn Park, Mark A. McGuire, William C. Davis, Gregory A. Bohach, Keun Seok Seo, Yong Ho Park
Publikováno v:
Journal of Leukocyte Biology. 85:606-616
Although many effects of staphylococcal superantigens (SAg) on T cells are well established, less is known about their effects on APC. In this study, bovine PBMC were stimulated with a low dose of staphylococcal enterotoxin C1 (SEC1). The phenotype o