Zobrazeno 1 - 10
of 477
pro vyhledávání: '"Gregory A, Cote"'
Autor:
Gaylor Boulay, Liliane C. Broye, Rui Dong, Sowmya Iyer, Rajendran Sanalkumar, Yu-Hang Xing, Rémi Buisson, Shruthi Rengarajan, Beverly Naigles, Benoît Duc, Angela Volorio, Mary E. Awad, Raffaele Renella, Ivan Chebib, G. Petur Nielsen, Edwin Choy, Gregory M. Cote, Lee Zou, Igor Letovanec, Ivan Stamenkovic, Miguel N. Rivera, Nicolò Riggi
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract EWS fusion oncoproteins underlie several human malignancies including Desmoplastic Small Round Cell Tumor (DSRCT), an aggressive cancer driven by EWS-WT1 fusion proteins. Here we combine chromatin occupancy and 3D profiles to identify EWS-WT
Externí odkaz:
https://doaj.org/article/fd00253648764577aeb52739a580a6a3
Autor:
Jonathan A. Saenger, MD, Ismail Tahir, MBBChBAO, Manuela Födinger, MD, Gregory M. Cote, MDPhD, Ashok Muniappan, MD, Florian J. Fintelmann, MD
Publikováno v:
Radiology Case Reports, Vol 18, Iss 10, Pp 3586-3591 (2023)
Patients with Li-Fraumeni syndrome (LFS) are prone to develop a variety of malignancies due to insufficient activity of the encoded tumor suppressor protein P53, including adrenocortical carcinoma, breast cancer, lung cancer, pancreatic cancer, and s
Externí odkaz:
https://doaj.org/article/3e4c389e21714c91a432c1b718520cba
Autor:
Emely Möller, Viviane Praz, Sanalkumar Rajendran, Rui Dong, Alexandra Cauderay, Yu-Hang Xing, Lukuo Lee, Carlo Fusco, Liliane C. Broye, Luisa Cironi, Sowmya Iyer, Shruthi Rengarajan, Mary E. Awad, Beverly Naigles, Igor Letovanec, Nicola Ormas, Giovanna Finzi, Stefano La Rosa, Fausto Sessa, Ivan Chebib, G. Petur Nielsen, Antonia Digklia, Dimitrios Spentzos, Gregory M. Cote, Edwin Choy, Martin Aryee, Ivan Stamenkovic, Gaylor Boulay, Miguel N. Rivera, Nicolò Riggi
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
The relationship between cellular histogenesis and molecular phenotypes for the EWSR1- ATF1 fusion in clear cell sarcoma (CCS) requires further characterization. Here, the authors investigate the EWSR1-ATF1 gene regulation networks in CCS cell lines,
Externí odkaz:
https://doaj.org/article/1755fdc1556a4ae2aea83d025041fcd5
Autor:
Christopher E. Lietz, Erik T. Newman, Andrew D. Kelly, David H. Xiang, Ziying Zhang, Caroline A. Luscko, Santiago A. Lozano-Calderon, David H. Ebb, Kevin A. Raskin, Gregory M. Cote, Edwin Choy, G. Petur Nielsen, Benjamin Haibe-Kains, Martin J. Aryee, Dimitrios Spentzos
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-20 (2022)
Christopher Lietz et al. examined genome-wide methylation in patient cohorts of primary osteosarcoma. Their results suggest that genomic hypomethylation is predictive of response to standard chemotherapy, and provide further insight into clinical imp
Externí odkaz:
https://doaj.org/article/90a95b6cbfc54bdc95e1e3c7e78c0b3f
Autor:
Andrés J. Lessing, Gregory M. Cote, Thomas F. DeLaney, Scott R. Plotkin, Kevin A. Raskin, Juan N. Lessing
Publikováno v:
Case Reports in Oncology, Vol 14, Iss 3, Pp 1342-1346 (2021)
Pseudoprogression, defined as the radiographic false appearance of disease progression, is not frequently observed in patients with malignant peripheral nerve sheath tumor (MPNST). We report on a case of a patient with neurofibromatosis type 1 (NF1)
Externí odkaz:
https://doaj.org/article/7e36e9d8017f4ff0904af119de87870b
Autor:
Peter J. Lee, Ali Lahooti, Stacey Culp, Andrew Boutsicaris, Phillip Holovach, Kayla Wozniak, Ila Lahooti, Pedram Paragomi, Alice Hinton, Ioannis Pothoulakis, Rupjyoti Talukdar, Rakesh Kochhar, Mahesh K. Goenka, Aiste Gulla, Jose A. Gonzalez, Vikesh Singh, Miguel Ferreira Bogado, Tyler Stevens, Sorin Traian Babu, Haq Nawaz, Silvia Cristina Gutierrez, Narcis Zarnescu, Gabriele Capurso, Jeffrey Easler, Konstantinos Triantafyllou, Mario Peláez Luna, Shyam Thakkar, Carlos Ocampo, Enrique de‐Madaria, Gregory A. Cote, Bechien U. Wu, Phil A. Hart, Somashekar G. Krishna, Luis Lara, Samuel Han, Georgios I. Papachristou
Publikováno v:
United European Gastroenterology Journal. 11:383-391
Autor:
Mrinal Gounder, Ravin Ratan, Thierry Alcindor, Patrick Schöffski, Winette T. van der Graaf, Breelyn A. Wilky, Richard F. Riedel, Allison Lim, L. Mary Smith, Stephanie Moody, Steven Attia, Sant Chawla, Gina D’Amato, Noah Federman, Priscilla Merriam, Brian A. Van Tine, Bruno Vincenzi, Charlotte Benson, Nam Quoc Bui, Rashmi Chugh, Gabriel Tinoco, John Charlson, Palma Dileo, Lee Hartner, Lore Lapeire, Filomena Mazzeo, Emanuela Palmerini, Peter Reichardt, Silvia Stacchiotti, Howard H. Bailey, Melissa A. Burgess, Gregory M. Cote, Lara E. Davis, Hari Deshpande, Hans Gelderblom, Giovanni Grignani, Elizabeth Loggers, Tony Philip, Joseph G. Pressey, Shivaani Kummar, Bernd Kasper
Publikováno v:
New England Journal of Medicine. 388:898-912
Autor:
Phil A. Hart, Dana K. Andersen, Erica Lyons, Gregory A. Cote, Zobeida Cruz-Monserrate, Robert H. Dworkin, B. Joseph Elmunzer, Evan L. Fogel, Christopher E. Forsmark, Ian Gilron, Megan Golden, Aysegul Gozu, Lindsay McNair, Stephen J. Pandol, Emily R. Perito, Anna Evans Phillips, Jennifer A. Rabbitts, David C. Whitcomb, John A. Windsor, Dhiraj Yadav, Tonya M. Palermo
Publikováno v:
Pancreas. 51(7)
Recurrent acute pancreatitis and chronic pancreatitis represent high morbidity diseases, which are frequently associated with chronic abdominal pain, pancreatic insufficiencies, and reduced quality of life. Currently, there are no therapies to revers
Autor:
Xiaoyang Li, Dylan C. Dean, Gregory M. Cote, Lee Zou, Francis J. Hornicek, Shengji Yu, Zhenfeng Duan
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 12 (2020)
Background: Ataxia-telangiectasia and Rad3 related protein kinase (ATR) is an essential regulator of the DNA damage response in various cancers; however, its expression and roles in osteosarcoma are unclear. We therefore chose to evaluate the signifi
Externí odkaz:
https://doaj.org/article/2d822bbd82db4cf9909685368289b740
Autor:
Parker L. Ellison, Nathan Holman, Kristin Wallace, Gregory A. Cote, B. Joseph Elmunzer, Andrew S. Brock
Publikováno v:
Endoscopy International Open, Vol 08, Iss 06, Pp E708-E716 (2020)
Background and study aims Existing guidelines recommend continuation of aspirin therapy prior to outpatient endoscopic procedures, as it reduces peri-procedural cardiovascular events and is not associated with an increased risk of bleeding. Despite t
Externí odkaz:
https://doaj.org/article/6a14a86fc6cf488d820f2257a2a8ef7e