Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Gregorio E. Fazzi"'
Autor:
Kelly Offermans, Josien C. A. Jenniskens, Colinda C. J. M. Simons, Iryna Samarska, Gregorio E. Fazzi, Jaleesa R. M. van derMeer, Kim M. Smits, Leo J. Schouten, Matty P. Weijenberg, Heike I. Grabsch, Piet A. van denBrandt
Publikováno v:
Cancer Medicine, Vol 12, Iss 2, Pp 1137-1156 (2023)
Abstract Background Previous research suggests that Warburg‐subtypes are related to potentially important survival differences in colorectal cancer (CRC) patients. In the present study, we investigated whether mutational subgroups based on somatic
Externí odkaz:
https://doaj.org/article/4f16f53a66a34d5caf70310b0fd58b56
Autor:
Han Jin, Pieter Goossens, Peter Juhasz, Wouter Eijgelaar, Marco Manca, Joël M. H. Karel, Evgueni Smirnov, Cornelis J. J. M. Sikkink, Barend M. E. Mees, Olivia Waring, Kim van Kuijk, Gregorio E. Fazzi, Marion J. J. Gijbels, Martina Kutmon, Chris T. A. Evelo, Ulf Hedin, Mat J. A. P. Daemen, Judith C. Sluimer, Ljubica Matic, Erik A. L. Biessen
Publikováno v:
Clinical and Translational Medicine, Vol 11, Iss 6, Pp n/a-n/a (2021)
Abstract Background While single‐omics analyses on human atherosclerotic plaque have been very useful to map stage‐ or disease‐related differences in expression, they only partly capture the array of changes in this tissue and suffer from scale
Externí odkaz:
https://doaj.org/article/97a35da6a68646a7861282ffbb332346
Autor:
Drolaiz H. W. Liu, Young-Woo Kim, Nina Sefcovicova, Jon P. Laye, Lindsay C. Hewitt, Andrew F. Irvine, Vincent Vromen, Yannick Janssen, Naser Davarzani, Gregorio E. Fazzi, Shahab Jolani, Veerle Melotte, Derek R. Magee, Myeong-Cherl Kook, Hyunki Kim, Rupert Langer, Jae-Ho Cheong, Heike I. Grabsch
Publikováno v:
British Journal of Cancer, 128(12), 2318-2325. Nature Publishing Group
Background: Only a subset of gastric cancer (GC) patients with stage II–III benefits from chemotherapy after surgery. Tumour infiltrating lymphocytes per area (TIL density) has been suggested as a potential predictive biomarker of chemotherapy bene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29d6ab45673e7601c5aa45e30593e3fe
https://doi.org/10.1038/s41416-023-02257-3
https://doi.org/10.1038/s41416-023-02257-3
Autor:
Josien C. A. Jenniskens, Kelly Offermans, Colinda C. J. M. Simons, Iryna Samarska, Gregorio E. Fazzi, Jaleesa R. M. van der Meer, Kim M. Smits, Leo J. Schouten, Matty P. Weijenberg, Heike I. Grabsch, Piet A. van den Brandt
Publikováno v:
Molecular Carcinogenesis, 61(12), 1099-1115. Wiley-Liss Inc.
KRAS mutations (KRASmut ), PIK3CAmut , BRAFmut , and deficient DNA mismatch repair (dMMR) have been associated with the Warburg effect. We previously reported differential associations between early-life energy balance-related factors (height, energy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::001acf417ce52d82ca00cdbaa5ec86fd
https://doi.org/10.1002/mc.23459
https://doi.org/10.1002/mc.23459
Autor:
Josien C. A. Jenniskens, Kelly Offermans, Colinda C. J. M. Simons, Iryna Samarska, Gregorio E. Fazzi, Jaleesa R. M. van der Meer, Kim M. Smits, Leo J. Schouten, Matty P. Weijenberg, Heike I. Grabsch, Piet A. van den Brandt
Publikováno v:
Journal of Cancer Research and Clinical Oncology, 148(10), 2723-2742. Springer, Cham
Introduction KRAS mutations (KRASmut), PIK3CAmut, BRAFmut, and mismatch repair deficiency (dMMR) have been associated with the Warburg-effect. We previously observed differential associations between energy balance-related factors (BMI, clothing-size
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60d9c0c94ce9b79f8068684ab5d7db02
https://doi.org/10.1007/s00432-022-04019-9
https://doi.org/10.1007/s00432-022-04019-9
Autor:
Josien C. A. Jenniskens, Kelly Offermans, Colinda C. J. M. Simons, Iryna Samarska, Gregorio E. Fazzi, Kim M. Smits, Leo J. Schouten, Matty P. Weijenberg, Heike I. Grabsch, Piet A. Brandt
Publikováno v:
International Journal of Cancer, 150(11), 1812-1824. Wiley
Early-life (childhood to adolescence) energy balance-related factors (height, energy restriction, BMI) have been associated with adult colorectal cancer (CRC) risk. Warburg-effect activation via PI3K/Akt-signaling might explain this link. We investig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdc7e0c4136d624c421e891cc8a8136f
https://cris.maastrichtuniversity.nl/en/publications/0c2e21ad-9a7c-48ca-8df4-37120bcb24c6
https://cris.maastrichtuniversity.nl/en/publications/0c2e21ad-9a7c-48ca-8df4-37120bcb24c6
Autor:
Kelly Offermans, Josien C. A. Jenniskens, Colinda C. J. M. Simons, Iryna Samarska, Gregorio E. Fazzi, Kim M. Smits, Leo J. Schouten, Matty P. Weijenberg, Heike I. Grabsch, Piet A. van den Brandt
Publikováno v:
Journal of Cancer Research and Clinical Oncology. Springer, Cham
Purpose Tumor location and tumor node metastasis (TNM) stage guide treatment decisions in colorectal cancer (CRC) patients. However, patients with the same disease stage do not benefit equally from adjuvant therapy. Hence, there remains an urgent cli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d45eceb139314169f8764df5b9044815
https://doi.org/10.1007/s00432-023-04581-w
https://doi.org/10.1007/s00432-023-04581-w
Autor:
Jorn P.J.M. Steeghs, Kelly Offermans, Josien C.A. Jenniskens, Iryna Samarska, Gregorio E. Fazzi, Piet A. van den Brandt, Heike I. Grabsch
Publikováno v:
Pathology - Research and Practice. 247:154518
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61c9b7853472092d0f2d202bd901eac9
https://doi.org/10.1016/j.prp.2023.154518
https://doi.org/10.1016/j.prp.2023.154518
Autor:
Kelly Offermans, Josien C. A. Jenniskens, Colinda C. J. M. Simons, Iryna Samarska, Gregorio E. Fazzi, Jaleesa R. M. van der Meer, Kim M. Smits, Leo J. Schouten, Matty P. Weijenberg, Heike I. Grabsch, Piet A. van den Brandt
Publikováno v:
Cancer Medicine, 12(2), 1137-1156. Wiley
BACKGROUND: Previous research suggests that Warburg-subtypes are related to potentially important survival differences in colorectal cancer (CRC) patients. In the present study, we investigated whether mutational subgroups based on somatic mutations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e6640084979c92e8d26baa94074368f
https://pubmed.ncbi.nlm.nih.gov/35785488
https://pubmed.ncbi.nlm.nih.gov/35785488
Autor:
Josien C.A. Jenniskens, Kelly Offermans, Colinda C.J.M. Simons, Iryna Samarska, Gregorio E. Fazzi, Kim M. Smits, Leo J. Schouten, Matty P. Weijenberg, Heike I. Grabsch, Piet A. van den Brandt
Publikováno v:
Cancer Epidemiology Biomarkers & Prevention, 31(3), 633-646. American Association for Cancer Research Inc.
Background: Energy balance–related factors [body mass index (BMI), waist circumference, physical activity] have been associated with colorectal cancer risk. Warburg effect activation via PI3K/Akt signaling is one of the proposed mechanisms. We inve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3243663725a3b2fba152001b8d1ea825
https://cris.maastrichtuniversity.nl/en/publications/63d5b39a-f8a2-4cb9-af95-faad197e8319
https://cris.maastrichtuniversity.nl/en/publications/63d5b39a-f8a2-4cb9-af95-faad197e8319
