Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Gregorio Alanis‐Lobato"'
Autor:
Chenfeng Zhang, Redas Dulinskas, Christian Ineichen, Alexandra Greter, Hannes Sigrist, Yulong Li, Gregorio Alanis-Lobato, Bastian Hengerer, Christopher R. Pryce
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-17 (2024)
Abstract Whilst reward pathologies are major and common in stress-related neuropsychiatric disorders, their neurobiology and treatment are poorly understood. Imaging studies in human reward pathology indicate attenuated BOLD activity in nucleus accum
Externí odkaz:
https://doaj.org/article/ddc3d87777844896bd33cd1e9176ceb5
Autor:
Lorraine Madur, Christian Ineichen, Giorgio Bergamini, Alexandra Greter, Giulia Poggi, Nagiua Cuomo-Haymour, Hannes Sigrist, Yaroslav Sych, Jean-Charles Paterna, Klaus D. Bornemann, Coralie Viollet, Francesc Fernandez-Albert, Gregorio Alanis-Lobato, Bastian Hengerer, Christopher R. Pryce
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-20 (2023)
Abstract Reduced reward interest/learning and reward-to-effort valuation are distinct, common symptoms in neuropsychiatric disorders for which chronic stress is a major aetiological factor. Glutamate neurons in basal amygdala (BA) project to various
Externí odkaz:
https://doaj.org/article/07210833de8e4c8cb484870cc8edadc8
Autor:
Sissy E. Wamaitha, Katarzyna J. Grybel, Gregorio Alanis-Lobato, Claudia Gerri, Sugako Ogushi, Afshan McCarthy, Shantha K. Mahadevaiah, Lyn Healy, Rebecca A. Lea, Miriam Molina-Arcas, Liani G. Devito, Kay Elder, Phil Snell, Leila Christie, Julian Downward, James M. A. Turner, Kathy K. Niakan
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
The signals regulating the establishment and maintenance of the pluripotent epiblast in human embryos are unclear. Here, the authors use a bioinformatics approach to identify the role of IGF1 in human embryo development, and from this, propose a cult
Externí odkaz:
https://doaj.org/article/104a33cb9a9247e1b51c23eb671ab8a2
Autor:
Ozge Gurbuz, Gregorio Alanis-Lobato, Sergio Picart-Armada, Miao Sun, Christian Haslinger, Nathan Lawless, Francesc Fernandez-Albert
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Indication expansion aims to find new indications for existing targets in order to accelerate the process of launching a new drug for a disease on the market. The rapid increase in data types and data sources for computational drug discovery has fost
Externí odkaz:
https://doaj.org/article/f4e2db66c554427080039e18a63f0ed6
Autor:
Francesco Della Valle, Manjula P. Thimma, Massimiliano Caiazzo, Salvatore Pulcrano, Mirko Celii, Sabir A. Adroub, Peng Liu, Gregorio Alanis-Lobato, Vania Broccoli, Valerio Orlando
Publikováno v:
Stem Cell Reports, Vol 14, Iss 1, Pp 60-74 (2020)
Summary: In mammals, LINE-1 (L1) retrotransposons constitute between 15% and 20% of the genome. Although only a few copies have retained the ability to retrotranspose, evidence in brain and differentiating pluripotent cells indicates that L1 retrotra
Externí odkaz:
https://doaj.org/article/5b877dab7e3747c58a1c35b460267621
Autor:
Stamatia Laidou, Gregorio Alanis-Lobato, Jan Pribyl, Tamás Raskó, Boris Tichy, Kamil Mikulasek, Maria Tsagiopoulou, Jan Oppelt, Georgia Kastrinaki, Maria Lefaki, Manvendra Singh, Annika Zink, Niki Chondrogianni, Fotis Psomopoulos, Alessandro Prigione, Zoltán Ivics, Sarka Pospisilova, Petr Skladal, Zsuzsanna Izsvák, Miguel A. Andrade-Navarro, Spyros Petrakis
Publikováno v:
Redox Biology, Vol 32, Iss , Pp - (2020)
Spinocerebellar ataxia type-1 (SCA1) is caused by an abnormally expanded polyglutamine (polyQ) tract in ataxin-1. These expansions are responsible for protein misfolding and self-assembly into intranuclear inclusion bodies (IIBs) that are somehow lin
Externí odkaz:
https://doaj.org/article/58f842a74f9f43cf914a2aa35353fc11
Publikováno v:
Applied Network Science, Vol 3, Iss 1, Pp 1-17 (2018)
Abstract There is an increasing accumulation of evidence supporting the existence of a hyperbolic geometry underlying the network representation of complex systems. In particular, it has been shown that the latent geometry of the human protein networ
Externí odkaz:
https://doaj.org/article/ea31b14848b34492b1b598e2579f73a4
Autor:
Khadija El Amrani, Gregorio Alanis-Lobato, Nancy Mah, Andreas Kurtz, Miguel A. Andrade-Navarro
Publikováno v:
PeerJ, Vol 7, p e6970 (2019)
The identification of condition-specific genes is key to advancing our understanding of cell fate decisions and disease development. Differential gene expression analysis (DGEA) has been the standard tool for this task. However, the amount of samples
Externí odkaz:
https://doaj.org/article/7c5f936875e44f9f9fb6d4f75ad803a4
Autor:
Kristina Kastano, Gábor Erdős, Pablo Mier, Gregorio Alanis-Lobato, Vasilis J. Promponas, Zsuzsanna Dosztányi, Miguel A. Andrade-Navarro
Publikováno v:
Biomolecules, Vol 10, Iss 10, p 1413 (2020)
Intrinsically disordered proteins (IDPs) contain regions lacking intrinsic globular structure (intrinsically disordered regions, IDRs). IDPs are present across the tree of life, with great variability of IDR type and frequency even between closely re
Externí odkaz:
https://doaj.org/article/4c1f0cc5f84f4716b084e3aad940f6e0
Autor:
Christian Dallago, Tatyana Goldberg, Miguel Angel Andrade-Navarro, Gregorio Alanis-Lobato, Burkhard Rost
Publikováno v:
F1000Research, Vol 6 (2018)
Many tools visualize protein-protein interaction (PPI) networks. The tool introduced here, CellMap, adds one crucial novelty by visualizing PPI networks in the context of subcellular localization, i.e. the location in the cell or cellular component i
Externí odkaz:
https://doaj.org/article/c30af46eaa16448c8971314d945ac292