The clinical impact of using complex molecular profiling strategies in routine oncology practice

Autor: Carlos Camps, Ramon De Las Penas, Ana Finzel, Carlos Regonesi, Helen Sadik, Gregori Ghitti, Timo Joensuu, Omalkhair Abulkhair, Anthony Kong, Philippe Aftimos, Jean-François Laes, Abdul Rahman El Kinge, Kefah Mokbel, Ibrahim Wahid, Christos Mikropoulos, Louis Kathan, K.M. Galal, Joaquim Bellmunt, Jesús García-Foncillas, Hady Ghanem, Rika Pienaar, Jean-Loup Mouysset, Fadi El Karak, Angel Garcia, James Mackay, Philippe Barthélémy, Timothy J. Perren, Guy Berchem, Petteri Hervonen, Sergey Odarchenko, Shadi S. Alkhayyat

Publikováno v: Oncotarget
r-FHPC. Repositorio Institucional de Producción Científica de la Fundación del Hospital Provincial de Castellón
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Oncotarget, 9 (29
r-FIHGUV. Repositorio Institucional de Producción Científica de la Fundación de Investigación del Hospital General de Valencia

Molecular profiling and functional assessment of signalling pathways of advanced solid tumours are becoming increasingly available. However, their clinical utility in guiding patients' treatment remains unknown. Here, we assessed whether molecular pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51a1b1bcd1c52c6f16f7fe50bd7ca7b8
http://hdl.handle.net/10230/41925

Stratification of tumors based on mTOR-pathway biomarkers

Autor: S Bastien Sauvage, Jean-François Laes, Gregori Ghitti

Publikováno v: Journal of Clinical Oncology. 35:e23097-e23097

e23097 Background: The mTOR pathway is often activated in human cancers. In this study, a total of 538 samples representing 40 different cancer types were analysed to evaluate the relationship between mTOR pathway activity and mutations in the upstre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7235a880913f81486a541630ad58094f
https://doi.org/10.1200/jco.2017.35.15_suppl.e23097