Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Gregor Winkels"'
Autor:
I. Jolanda M. de Vries, Carl G. Figdor, Cornelis J.A. Punt, Winald R. Gerritsen, Christian U. Blank, Sander Kelderman, Joannes F.M. Jacobs, Rutger H.T. Koornstra, Sandra A.J. Croockewit, Roel D.M. Mus, Marieke E.B. Welzen, Michelle M. van Rossum, Willeke A.M. Blokx, Katja Petry, Gregor Winkels, Jurjen Tel, Tom G.M. van Oorschot, Michel A.M. Olde Nordkamp, Jeanette M. Pots, Annemiek J. de Boer, Nicole M. Scharenborg, Mandy W.M.M. van de Rakt, Tjitske Duiveman-de Boer, Erik H.J.G. Aarntzen, Florian Wimmers, Harm Westdorp, Kalijn F. Bol, Gerty Schreibelt
Supplementary Figure 3. KLH-specific immune responses before and after DC vaccination. (A) KLH-specific T cell proliferation was analyzed before the first vaccination and after each DC vaccination during the first vaccination cycle in peripheral bloo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ce748475936725a8bb47b16d85c4c40
https://doi.org/10.1158/1078-0432.22457933.v1
https://doi.org/10.1158/1078-0432.22457933.v1
Autor:
I. Jolanda M. de Vries, Carl G. Figdor, Cornelis J.A. Punt, Winald R. Gerritsen, Christian U. Blank, Sander Kelderman, Joannes F.M. Jacobs, Rutger H.T. Koornstra, Sandra A.J. Croockewit, Roel D.M. Mus, Marieke E.B. Welzen, Michelle M. van Rossum, Willeke A.M. Blokx, Katja Petry, Gregor Winkels, Jurjen Tel, Tom G.M. van Oorschot, Michel A.M. Olde Nordkamp, Jeanette M. Pots, Annemiek J. de Boer, Nicole M. Scharenborg, Mandy W.M.M. van de Rakt, Tjitske Duiveman-de Boer, Erik H.J.G. Aarntzen, Florian Wimmers, Harm Westdorp, Kalijn F. Bol, Gerty Schreibelt
Purpose: Thus far, dendritic cell (DC)-based immunotherapy of cancer was primarily based on in vitro–generated monocyte-derived DCs, which require extensive in vitro manipulation. Here, we report on a clinical study exploiting primary CD1c+ myeloid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::492a00959142946a6e6448b4074be089
https://doi.org/10.1158/1078-0432.c.6523763.v1
https://doi.org/10.1158/1078-0432.c.6523763.v1
Autor:
I. Jolanda M. de Vries, Carl G. Figdor, Cornelis J.A. Punt, Winald R. Gerritsen, Christian U. Blank, Sander Kelderman, Joannes F.M. Jacobs, Rutger H.T. Koornstra, Sandra A.J. Croockewit, Roel D.M. Mus, Marieke E.B. Welzen, Michelle M. van Rossum, Willeke A.M. Blokx, Katja Petry, Gregor Winkels, Jurjen Tel, Tom G.M. van Oorschot, Michel A.M. Olde Nordkamp, Jeanette M. Pots, Annemiek J. de Boer, Nicole M. Scharenborg, Mandy W.M.M. van de Rakt, Tjitske Duiveman-de Boer, Erik H.J.G. Aarntzen, Florian Wimmers, Harm Westdorp, Kalijn F. Bol, Gerty Schreibelt
Supplementary Figure 1. Schematic overview of the 44 h mDC vaccine preparation cycle and vaccination strategy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d06d6192c935b44e17609dce62fe016
https://doi.org/10.1158/1078-0432.22457939
https://doi.org/10.1158/1078-0432.22457939
Autor:
I. Jolanda M. de Vries, Carl G. Figdor, Cornelis J.A. Punt, Pierre G. Coulie, Gregor Winkels, Michelle van Rossum, Wim J.G. Oyen, Sandra Croockewit, Otto C. Boerman, Daniel Benitez-Ribas, Barbara M. Schulte, Gerty Schreibelt, Tetsuro Baba, Erik H.J.G. Aarntzen, Jurjen Tel
Supplementary Table 2 PDF file - 30K, Patient characteristics and historical controls
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14de4c066e6e99d9e3d67a7e4668bc6f
https://doi.org/10.1158/0008-5472.22398653
https://doi.org/10.1158/0008-5472.22398653
Autor:
I. Jolanda M. de Vries, Carl G. Figdor, Cornelis J.A. Punt, Pierre G. Coulie, Gregor Winkels, Michelle van Rossum, Wim J.G. Oyen, Sandra Croockewit, Otto C. Boerman, Daniel Benitez-Ribas, Barbara M. Schulte, Gerty Schreibelt, Tetsuro Baba, Erik H.J.G. Aarntzen, Jurjen Tel
Supplementary Figure 2 PDF file - 46K, Supplementary Figure 2 Plasmacytoid DCs acquire CCL21-driven chemotactic ability upon activation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eba622aa9f0b2619d7336523da598e0
https://doi.org/10.1158/0008-5472.22398659
https://doi.org/10.1158/0008-5472.22398659
Autor:
I. Jolanda M. de Vries, Carl G. Figdor, Cornelis J.A. Punt, Pierre G. Coulie, Gregor Winkels, Michelle van Rossum, Wim J.G. Oyen, Sandra Croockewit, Otto C. Boerman, Daniel Benitez-Ribas, Barbara M. Schulte, Gerty Schreibelt, Tetsuro Baba, Erik H.J.G. Aarntzen, Jurjen Tel
Supplementary Figure 1 PDF file - 34K, Supplementary Figure 1 CliniMACS-based pDC isolation is feasible
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20d5ede416f5d24d43eb0b30923c7930
https://doi.org/10.1158/0008-5472.22398662
https://doi.org/10.1158/0008-5472.22398662
Autor:
I. Jolanda M. de Vries, Carl G. Figdor, Cornelis J.A. Punt, Pierre G. Coulie, Gregor Winkels, Michelle van Rossum, Wim J.G. Oyen, Sandra Croockewit, Otto C. Boerman, Daniel Benitez-Ribas, Barbara M. Schulte, Gerty Schreibelt, Tetsuro Baba, Erik H.J.G. Aarntzen, Jurjen Tel
Supplementary Table 1 PDF file - 29K, Induration (mm) of the different injection sites in the DTH skin test
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::817e38b4b1b29a9e26779be20b4d27b7
https://doi.org/10.1158/0008-5472.22398656.v1
https://doi.org/10.1158/0008-5472.22398656.v1
Autor:
Verena Traska, Mario Assenmacher, Gregor Winkels, Lennart Wessels, Marek Wieczorek, Sebastian Flade, Anna Baranska, Marc Schuster, Burhan Karaca
Publikováno v:
Clinical Cancer Research. 27:P23-P23
Introduction: The emergence of SARS-CoV-2 virus, which causes COVID-19, is a major global health hazard. Therefore, a comprehensive characterization of the humoral and cellular immune responses to this virus is essential to combat the COVID-19 pandem
Autor:
Simon Lennartz, Dominik Lock, Carolin Kolbe, Gregor Winkels, Mario Assenmacher, Andrew Kaiser
Publikováno v:
The Journal of Immunology. 204:86.28-86.28
In recent years, CAR T cell mediated immunotherapy has shown clinical efficacy in the fight against cancer. Increased research efforts to address several challenges associated with CAR T cell therapy for solid tumor treatment for instance, such as po
Autor:
Gregor Winkels, Juliet Quirk, Eugene Maraskovsky, Lauren Seddon, Lisa M. Ebert, Jonathan Cebon, Tsin Yee Tai, Leone Morris, Frederick Wittke, Weisan Chen, Ian D. Davis, Judy Browning, Genevieve Whitty, Duncan MacGregor, Lena Miloradovic, Tina Cavicchiolo, Regina Alex, Heather Jackson
Publikováno v:
Immunotherapy. 9(3)
Aim: Pilot clinical trial of NY-ESO-1 (ESO) protein in ISCOMATRIX™ adjuvant pulsed onto peripheral blood dendritic cells (PBDC), to ascertain feasibility, evaluate toxicity and assess induction of ESO-specific immune responses. Patients & methods: