Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Gregor Sutcliffe"'
Autor:
Masashi Yanagisawa, Christopher J. Winrow, Neil Upton, Gregor Sutcliffe, Jerome M Siegel, Takeshi Sakurai, John Renger, Rod Porter, Terrence P. McDonald, Jyrki P. Kukkonen, Thomas Kilduff, Laura Jacobson, Daniel Hoyer, Debbie Hartman, Luis De Lecea, Paul Coleman, Pascal Bonaventure, Gary Aston-Jones
Publikováno v:
IUPHAR/BPS Guide to Pharmacology CITE. 2023
Orexin receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Orexin receptors [43]) are activated by the endogenous polypeptides orexin-A and orexin-B (also known as hypocretin-1 and -2; 33 and 28 aa) derived from a common precursor, pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4494e816ff2e1ff073075e99b23a0035
https://doi.org/10.2218/gtopdb/f51/2023.1
https://doi.org/10.2218/gtopdb/f51/2023.1
Autor:
Paula A. Desplats, Christine A. Denny, Kristi E. Kass, Tim Gilmartin, Steven R. Head, J. Gregor Sutcliffe, Thomas N. Seyfried, Elizabeth A. Thomas
Publikováno v:
Neurobiology of Disease, Vol 27, Iss 3, Pp 265-277 (2007)
We have explored genome-wide expression of genes related to glycobiology in exon 1 transgenic Huntington's disease (HD) mice using a custom-designed GLYCOv2 chip and Affymetrix microarray analyses. We validated, using quantitative real-time PCR, abno
Externí odkaz:
https://doaj.org/article/2c9255a158694d8b9a4d4a983dbcd39d
Autor:
Tracey L. Papenfuss, J. Cameron Thrash, Patricia E. Danielson, Pamela E. Foye, Brian S. Hllbrush, J. Gregor Sutcliffe, Caroline C. Whitacre, Monica J. Carson
Publikováno v:
The Scientific World Journal, Vol 7, Pp 112-120 (2007)
Microglia are the tissue macrophages of the CNS. Microglial activation coupled with macrophage infiltration is a common feature of many classic neurodegenerative disorders. The absence of cell-type specific markers has confounded and complicated the
Externí odkaz:
https://doaj.org/article/591e5862f31c4ab799026b7616ae5ab9
Publikováno v:
Molecular Regulation of Arousal States ISBN: 9780849333613
Molecular Regulation of Arousal States
Molecular Regulation of Arousal States
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71a4bcb27ba1f82c57966a9023cae3e6
https://doi.org/10.1201/9780429186844-9
https://doi.org/10.1201/9780429186844-9
Publikováno v:
Biotechnology & Biological Frontiers ISBN: 9780429050329
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::426fa3cdeeab9cf09d2f81648a7d014f
https://doi.org/10.4324/9780429050329-9
https://doi.org/10.4324/9780429050329-9
Publikováno v:
Journal of Neuroscience Research. 89:808-814
Three loci that modify β-amyloid (Aβ) accumulation and deposition in the brains of a mouse model of Alzheimer's disease have been previously described. One encompasses the Psen2 gene encoding presenilin 2, a component of the γ-secretase activity r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c4cb2b7fdd7e5e3e23c530a3edeab0d
https://doi.org/10.1002/jnr.22603
https://doi.org/10.1002/jnr.22603
Autor:
Caroline Lanigan, Wei-li Chang, J. Gregor Sutcliffe, Brian Dean, Bin Tang, Elizabeth A. Thomas
Publikováno v:
Aging Cell. 8:339-342
We examined genome-wide expression datasets from human prefrontal cortex of normal and schizophrenic individuals ranging from 19 to 81 years of age. We found that changes in gene expression that are correlated with aging in normal subjects differ dra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a35eaa3d64c0e90f69f003e49f5974bc
https://doi.org/10.1111/j.1474-9726.2009.00468.x
https://doi.org/10.1111/j.1474-9726.2009.00468.x
Autor:
Monica J. Carson, Benoît Melchior, David Lo, Kokoechat Masek, J. Gregor Sutcliffe, Patria E. Danielson, Christoph D. Schmid, Shweta S. Puntambekar
Publikováno v:
Journal of Neurochemistry
Schmid, CD; Melchior, B; Masek, K; Puntambekar, SS; Danielson, PE; Lo, DD; et al.(2009). Differential gene expression in LPS/IFNγ activated microglia and macrophages: In vitro versus in vivo. Journal of Neurochemistry, 109(SUPPL. 1), 117-125. doi: 10.1111/j.1471-4159.2009.05984.x. UC Riverside: Retrieved from: http://www.escholarship.org/uc/item/30g6n2hw
Schmid, CD; Melchior, B; Masek, K; Puntambekar, SS; Danielson, PE; Lo, DD; et al.(2009). Differential gene expression in LPS/IFNγ activated microglia and macrophages: In vitro versus in vivo. Journal of Neurochemistry, 109(SUPPL. 1), 117-125. doi: 10.1111/j.1471-4159.2009.05984.x. UC Riverside: Retrieved from: http://www.escholarship.org/uc/item/30g6n2hw
Two different macrophage populations contribute to CNS neuroinflammation: CNS-resident microglia and CNS-infiltrating peripheral macrophages. Markers distinguishing these two populations in tissue sections have not been identified. Therefore, we comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e304a75a35cd1cb1d9d3b13b43211eff
http://europepmc.org/articles/PMC2766614
http://europepmc.org/articles/PMC2766614
Publikováno v:
Journal of Neurochemistry. 79:1059-1064
Apolipoprotein D (apoD) expression is known to be elevated in select regions of rodent and human brain in association with different types of CNS pathology. To investigate a potential role for apoD in the neuropathology of Alzheimer's disease, we hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8abeb04311c3597036c59b99ded009e0
https://doi.org/10.1046/j.1471-4159.2001.00654.x
https://doi.org/10.1046/j.1471-4159.2001.00654.x
Autor:
Luis de Lecea, J. Gregor Sutcliffe
Publikováno v:
FEBS Journal. 272:5675-5688
The hypocretins (also called the orexins) are two neuropeptides derived from the same precursor whose expression is restricted to a few thousand neurons of the lateral hypothalamus. Two G-protein coupled receptors for the hypocretins have been identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81249b87148ce2a487940445e15818f7
https://doi.org/10.1111/j.1742-4658.2005.04981.x
https://doi.org/10.1111/j.1742-4658.2005.04981.x