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pro vyhledávání: '"Gregor S. Cremosnik"'
Autor:
Felix Otte, Gregor S. Cremosnik, Jie Liu, Herbert Waldmann, Sonja Sievers, Axel Pahl, Carsten Strohmann
Publikováno v:
Angewandte Chemie (International Ed. in English)
Angewandte Chemie International Edition
Angewandte Chemie International Edition
Natural product (NP) structures are a rich source of inspiration for the discovery of new biologically relevant chemical matter. In natural product inspired pseudo‐NPs, NP‐derived fragments are combined de novo in unprecedented arrangements. Desc
Publikováno v:
Natural Product Reports
Covering: up to 2020 Natural products (NPs) provide inspiration for the design of biologically active compounds and libraries. In this review, we cover several experimental and in silico approaches, which have been used to simplify NPs and guide NP-b
Publikováno v:
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
P-Amidites can be used in iterative couplings to selectively give mixed P(III) -P(V) anhydrides. These intermediates can be oxidized followed by a rapid removal of the two terminal fluorenylmethyl groups. An iterative synthesis (coupling, oxidation,
Publikováno v:
Angewandte Chemie. 126:290-294
Autor:
André C. Müller, Giulio Superti-Furga, Henning J. Jessen, Keiryn L. Bennett, Roberto Giambruno, Alexandre Hofer, Gregor S. Cremosnik, Claudia Trefzer
Publikováno v:
Chemistry-A European Journal
Phosphoanhydrides (P-anhydrides) are ubiquitously occurring modifications in nature. Nucleotides and their conjugates, for example, are among the most important building blocks and signaling molecules in cell biology. To study and manipulate their bi