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pro vyhledávání: '"Gregor S Kijanka"'
Autor:
Julie-Ann O'Reilly, Jenny Fitzgerald, Seán Fitzgerald, Dermot Kenny, Elaine W Kay, Richard O'Kennedy, Gregor S Kijanka
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123469 (2015)
Colorectal cancer is one of the most common cancers worldwide with almost 700,000 deaths every year. Detection of colorectal cancer at an early stage significantly improves patient survival. Cancer-specific autoantibodies found in sera of cancer pati
Externí odkaz:
https://doaj.org/article/f220ca938e2740c5af953e35adfb18d6
Publikováno v:
F1000Research, Vol 5 (2017)
Protein arrays are frequently used to profile antibody repertoires in humans and animals. High-throughput protein array characterisation of complex antibody repertoires necessitates the use of extensively validated secondary detection antibodies. Thi
Publikováno v:
F1000Research, Vol 5 (2016)
Protein arrays are frequently used to profile antibody repertoires in humans and animals. High-throughput protein array characterisation of complex antibody repertoires requires a platform-dependent, lot-to-lot validation of secondary detection antib
Autor:
Seán, Fitzgerald, Katherine M, Sheehan, Anthony, O'Grady, Dermot, Kenny, Richard, O'Kennedy, Elaine W, Kay, Gregor S, Kijanka
Publikováno v:
Journal of gastroenterology and hepatology. 28(6)
TRIM28 is a multi-domain nuclear protein with pleotropic effects in both normal and tumor cells. In this study, TRIM28 expression in epithelial and stromal tumor microenvironment and its prognostic role in colorectal cancer were investigated.Immunohi
Stromal TRIM28-associated signaling pathway modulation within the colorectal cancer microenvironment
Autor:
Seán Fitzgerald, Virginia Espina, Lance Liotta, Katherine M. Sheehan, Anthony O’Grady, Robert Cummins, Richard O’Kennedy, Elaine W. Kay, Gregor S. Kijanka
Publikováno v:
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-11 (2018)
Abstract Background Stromal gene expression patterns predict patient outcomes in colorectal cancer. TRIM28 is a transcriptional co-repressor that regulates an abundance of genes through the KRAB domain family of transcription factors. We have previou
Externí odkaz:
https://doaj.org/article/cb14ff19e39146839e9dcb9f4f27b837