Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Gregor R Weber"'
Publikováno v:
Neural Regeneration Research, Vol 16, Iss 8, Pp 1524-1528 (2021)
The canonical Wnt/β-catenin signaling pathway has been shown to play a major role during embryonic development and maturation of the central nervous system including the retina. It has a significant impact on retinal vessel formation and maturation,
Externí odkaz:
https://doaj.org/article/ff1f2c36104544f1b405dfd02596fd63
Publikováno v:
Neural Regeneration Research
Neural Regeneration Research, Vol 16, Iss 8, Pp 1524-1528 (2021)
Neural Regeneration Research, Vol 16, Iss 8, Pp 1524-1528 (2021)
The canonical Wnt/β-catenin signaling pathway has been shown to play a major role during embryonic development and maturation of the central nervous system including the retina. It has a significant impact on retinal vessel formation and maturation,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f80f1c1544a8b079b984c3acccddbe2f
http://europepmc.org/articles/PMC8323680
http://europepmc.org/articles/PMC8323680
Autor:
Andrea E. Dillinger, Renato V. Iozzo, Magdalena Schneider, Rudolf Fuchshofer, Gregor R Weber, Andreas Ohlmann, Ernst R. Tamm, Harry A. Quigley, Ramona Pawlak, Sabrina Kuespert
Publikováno v:
Matrix biology : journal of the International Society for Matrix Biology. 97
Primary open-angle glaucoma a neurodegenerative disorder characterized by degeneration of optic nerve axons, is a frequent cause of vision loss and blindness worldwide. Several randomized multicenter studies have identified intraocular pressure as th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28de6c029e99e8ae0b8186f4138a2941
https://pubmed.ncbi.nlm.nih.gov/33582236
https://pubmed.ncbi.nlm.nih.gov/33582236
Autor:
Rudolf Fuchshofer, Andreas Ohlmann, Michael R. Bösl, Roswitha Seitz, Gregor R. Weber, Herbert Jägle, Ernst R. Tamm, Stephanie Leopold, Ludwig F. Zeilbeck
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Scientific Reports
Scientific Reports
Norrin is a secreted signaling molecule activating the Wnt/β-catenin pathway. Since Norrin protects retinal neurons from experimental acute injury, we were interested to learn if Norrin attenuates chronic damage of retinal ganglion cells (RGC) and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::694ddb30f80c4624b7085d0d946871b8
http://link.springer.com/article/10.1038/s41598-017-14423-8
http://link.springer.com/article/10.1038/s41598-017-14423-8
Autor:
Fabian, Boesl, Konstantin, Drexler, Birgit, Müller, Roswitha, Seitz, Gregor R, Weber, Siegfried G, Priglinger, Rudolf, Fuchshofer, Ernst R, Tamm, Andreas, Ohlmann
Publikováno v:
Molecular Vision
Purpose To analyze whether activation of endogenous wingless (Wnt)/β-catenin signaling in Müller cells is involved in protection of retinal ganglion cells (RGCs) following excitotoxic damage. Methods Transgenic mice with a tamoxifen-dependent β-ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c35f5e733abafdd457fb496a6141d0f2
https://pubmed.ncbi.nlm.nih.gov/32180679
https://pubmed.ncbi.nlm.nih.gov/32180679
Autor:
Kristin Perkumas, Gregor R. Weber, Franziska Froemel, Andrea E. Dillinger, Rudolf Fuchshofer, Michaela Guter, Andreas Ohlmann, Miriam Breunig, W. Daniel Stamer
Glaucoma is the second leading cause of blindness worldwide, often associated with elevated intraocular pressure. Connective tissue growth factor (CTGF) is a mediator of pathological effects in the trabecular meshwork (TM) and Schlemm's canal (SC). A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e23571b6f83c1235ae50e228d2ac098e
https://europepmc.org/articles/PMC6599181/
https://europepmc.org/articles/PMC6599181/
Autor:
Gregor R. Weber, Roswitha Seitz, Rudolf Fuchshofer, Andreas Ohlmann, Sebastian Albrecht, Ernst R. Tamm
Publikováno v:
Investigative ophthalmologyvisual science. 59(6)
PURPOSE. Norrin is essential for the formation of the retinal vasculature during development and promotes its repair after damage via activation of Wnt/beta-catenin signaling. Since retinal TGF-beta signaling has essentially opposite effects on the r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c3c777f88e3b50ac4787e8cfc4ac6f3
https://pubmed.ncbi.nlm.nih.gov/29715368
https://pubmed.ncbi.nlm.nih.gov/29715368
Autor:
Andrea E. Dillinger, Gregor R. Weber, Matthias Mayer, Magdalena Schneider, Corinna Göppner, Andreas Ohlmann, Mikhail Shamonin, Gareth J. Monkman, Rudolf Fuchshofer
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
In primary open-angle glaucoma (POAG), a neurodegenerative disease of the optic nerve (ON) and leading cause of blindness, the optic nerve head (ONH) undergoes marked structural extracellular matrix (ECM) changes, which contribute to its permanent de
Externí odkaz:
https://doaj.org/article/51eaaa84df79459b99db71fbc9e113e5