Zobrazeno 1 - 10
of 153
pro vyhledávání: '"Gregor Kuhlenbäumer"'
Autor:
Justina Dargvainiene, Ulf Jensen‐Kondering, Benjamin Bender, Daniela Berg, Norbert Brüggemann, Charlotte Flüh, Robert Markewitz, Alexander Neumann, Benjamin Röben, Christoph Röcken, Georg Royl, Claudia Schulte, Klaus‐Peter Wandinger, Caroline Weiler, Nils G. Margraf, Gregor Kuhlenbäumer
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 3, Pp 806-811 (2024)
Abstract Differential diagnosis between Alzheimer's disease (AD) and cerebral amyloid angiopathy (CAA) using cerebrospinal fluid (CSF) biomarkers is challenging. A recent study suggested that the addition of Aβ38 and Aβ43 to a standard AD biomarker
Externí odkaz:
https://doaj.org/article/b818d4c230ba4d67a26983a4f6badad1
Autor:
Vicente Peris Sempere, Guo Luo, Sergio Muñiz-Castrillo, Anne-Laurie Pinto, Géraldine Picard, Véronique Rogemond, Maarten J. Titulaer, Carsten Finke, Frank Leypoldt, Gregor Kuhlenbäumer, GENERATE study group, Hannah F. Jones, Russell C. Dale, Sophie Binks, Sarosh R. Irani, Anna E. Bastiaansen, Juna M. de Vries, Marienke A. A. M. de Bruijn, Dave L. Roelen, Tae-Joon Kim, Kon Chu, Soon-Tae Lee, Takamichi Kanbayashi, Nicholas R. Pollock, Katherine M. Kichula, Abigail Mumme-Monheit, Jérôme Honnorat, Paul J. Norman, Emmanuel Mignot
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionGenetic predisposition to autoimmune encephalitis with antibodies against N-methyl-D-aspartate receptor (NMDAR) is poorly understood. Given the diversity of associated environmental factors (tumors, infections), we hypothesized that human
Externí odkaz:
https://doaj.org/article/e4b45e262d7d4c94a367c4764816edda
Autor:
Patricia Weede, Piotr Dariusz Smietana, Gregor Kuhlenbäumer, Günther Deuschl, Gerhard Schmidt
Publikováno v:
Information, Vol 15, Iss 4, p 231 (2024)
Accurate tremor classification is crucial for effective patient management and treatment. However, clinical diagnoses are often hindered by misdiagnoses, necessitating the development of robust technical methods. Here, we present a two-stage convolut
Externí odkaz:
https://doaj.org/article/aa0745e167a84b729e2b3f1d8d8bad56
Autor:
Monika Huhndorf, Christoph Röcken, Charlotte Flüh, Caroline Weiler, Gregor Kuhlenbäumer, Nora Tegeler, Hannes Schacht, Alexander Neumann, Nils G. Margraf, Ulf Jensen-Kondering
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
BackgroundCerebral amyloid angiopathy (CAA) is a common disease and the most common cause of lobar hemorrhages in the elderly. Usually, deep-seated microhemorrhages preclude the diagnosis of CAA. In this study, we sought to estimate the frequency of
Externí odkaz:
https://doaj.org/article/8ba395befd384959a478beef0a450499
Autor:
Nils G. Margraf, Ulf Jensen-Kondering, Caroline Weiler, Frank Leypoldt, Walter Maetzler, Sarah Philippen, Thorsten Bartsch, Charlotte Flüh, Christoph Röcken, Bettina Möller, Georg Royl, Alexander Neumann, Norbert Brüggemann, Benjamin Roeben, Claudia Schulte, Benjamin Bender, Daniela Berg, Gregor Kuhlenbäumer
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
BackgroundTo evaluate the diagnostic accuracy of cerebrospinal fluid (CSF) biomarkers in patients with probable cerebral amyloid angiopathy (CAA) according to the modified Boston criteria in a retrospective multicentric cohort.MethodsBeta-amyloid 1-4
Externí odkaz:
https://doaj.org/article/f51fab52ef8b4d2e9711cd97d5adba34
Autor:
Ingo Helbig, Giulia Barcia, Manuela Pendziwiat, Shiva Ganesan, Stefanie H. Mueller, Katherine L. Helbig, Priya Vaidiswaran, Julie Xian, Peter D. Galer, Zaid Afawi, Nicola Specchio, Gerhard Kluger, Gregor Kuhlenbäumer, Silke Appenzeller, Michael Wittig, Uri Kramer, Andreas vanBaalen, Rima Nabbout, FIRES Genetics Study Group
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 7, Iss 8, Pp 1429-1435 (2020)
Abstract Febrile infection‐related epilepsy syndrome (FIRES) is a devastating epilepsy characterized by new‐onset refractory status epilepticus with a prior febrile infection. We performed exome sequencing in 50 individuals with FIRES, including
Externí odkaz:
https://doaj.org/article/2e6f3dac92674d6d82bb4276627bd400
Autor:
Johanna Geritz, Sara Maetzold, Maren Steffen, Andrea Pilotto, Marta F. Corrà, Mariana Moscovich, Maria C. Rizzetti, Barbara Borroni, Alessandro Padovani, Annekathrin Alpes, Corinna Bang, Igor Barcellos, Ralf Baron, Thorsten Bartsch, Jos S. Becktepe, Daniela Berg, Lu M. Bergeest, Philipp Bergmann, Raquel Bouça-Machado, Michael Drey, Morad Elshehabi, Susan Farahmandi, Joaquim J. Ferreira, Andre Franke, Anja Friederich, Corinna Geisler, Philipp Hüllemann, Janne Gierthmühlen, Oliver Granert, Sebastian Heinzel, Maren K. Heller, Markus A. Hobert, Marc Hofmann, Björn Jemlich, Laura Kerkmann, Stephanie Knüpfer, Katharina Krause, Maximilian Kress, Sonja Krupp, Jennifer Kudelka, Gregor Kuhlenbäumer, Roland Kurth, Frank Leypoldt, Corina Maetzler, Luis F. Maia, Andreas Moewius, Patricia Neumann, Katharina Niemann, Christian T. Ortlieb, Steffen Paschen, Minh H. Pham, Thomas Puehler, Franziska Radloff, Christian Riedel, Marten Rogalski, Simone Sablowsky, Elena M. Schanz, Linda Schebesta, Andreas Schicketmüller, Simone Studt, Martina Thieves, Lars Tönges, Sebastian Ullrich, Peter P. Urban, Nuno Vila-Chã, Anna Wiegard, Elke Warmerdam, Tobias Warnecke, Michael Weiss, Julius Welzel, Clint Hansen, Walter Maetzler
Publikováno v:
BMC Geriatrics, Vol 20, Iss 1, Pp 1-13 (2020)
Abstract Background Motor and cognitive deficits and consequently mobility problems are common in geriatric patients. The currently available methods for diagnosis and for the evaluation of treatment in this vulnerable cohort are limited. The aims of
Externí odkaz:
https://doaj.org/article/b663fd6675b5463f917fc523e3b49444
Autor:
Guillermo G. Torres, Janina Dose, Tim P. Hasenbein, Marianne Nygaard, Ben Krause-Kyora, Jonas Mengel-From, Kaare Christensen, Karen Andersen-Ranberg, Daniel Kolbe, Wolfgang Lieb, Matthias Laudes, Siegfried Görg, Stefan Schreiber, Andre Franke, Amke Caliebe, Gregor Kuhlenbäumer, Almut Nebel
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 18, p 10949 (2022)
Longevity is a complex phenotype influenced by both environmental and genetic factors. The genetic contribution is estimated at about 25%. Despite extensive research efforts, only a few longevity genes have been validated across populations. Long-liv
Externí odkaz:
https://doaj.org/article/cd36c8d2ac8343a6bd4982ea6633a817
Autor:
Ali S. Shalash, Thomas W. Rösler, Ibrahim Y. Abdelrahman, Hatem S. Abulmakarem, Stefanie H. Müller, Franziska Hopfner, Gregor Kuhlenbäumer, Günter U. Höglinger, Mohamed Salama
Publikováno v:
Heliyon, Vol 7, Iss 7, Pp e07469- (2021)
Pantothenate kinase-associated neurodegeneration (PKAN) is a rare hereditary neurodegenerative disease characterized by an accumulation of iron within the brain. In the present report, we describe a family with 4 affected siblings presenting with var
Externí odkaz:
https://doaj.org/article/f483bbcf535747b284208eaac29143b7
Autor:
Franziska Hopfner, Stefanie H. Müller, Dagmar Steppat, Joanna Miller, Nele Schmidt, Klaus-Peter Wandinger, Frank Leypoldt, Daniela Berg, Andre Franke, Wolfgang Lieb, Lukas Tittmann, Monika Balzer-Geldsetzer, Simon Baudrexel, Richard Dodel, Ruediger Hilker-Roggendorf, Elke Kalbe, Jan Kassubek, Thomas Klockgether, Inga Liepelt-Scarfone, Brit Mollenhauer, Petra Neuser, Kathrin Reetz, Oliver Riedel, Claudia Schulte, Jörg B. Schulz, Annika Spottke, Alexander Storch, Claudia Trenkwalder, Hans-Ulrich Wittchen, Karsten Witt, Ullrich Wüllner, Günther Deuschl, Gregor Kuhlenbäumer
Publikováno v:
Translational Neurodegeneration, Vol 8, Iss 1, Pp 1-7 (2019)
Abstract Background IgG-class autoantibodies to N-Methyl-D-Aspartate (NMDA)-type glutamate receptors define a novel entity of autoimmune encephalitis. Studies examining the prevalence of NMDA IgA/IgM antibodies in patients with Parkinson disease with
Externí odkaz:
https://doaj.org/article/29f195f4aea44b509b6a257ca56a5335