Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Gregor Gryglewski"'
Autor:
Marie Spies, Matej Murgaš, Chrysoula Vraka, Cecile Philippe, Gregor Gryglewski, Lukas Nics, Theresa Balber, Pia Baldinger-Melich, Annette M. Hartmann, Dan Rujescu, Marcus Hacker, Edda Winkler-Pjrek, Dietmar Winkler, Rupert Lanzenberger
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-7 (2023)
Abstract Variants within the monoamine oxidase A (MAO-A, MAOA) and tryptophan hydroxylase 2 (TPH2) genes, the main enzymes in cerebral serotonin (5-HT) turnover, affect risk for depression. Depressed cohorts show increased cerebral MAO-A in positron
Externí odkaz:
https://doaj.org/article/9ecc75b305cf4506a06a2fedef345416
Autor:
Lucas Rischka, Matej Murgaš, Verena Pichler, Chrysoula Vraka, Ivo Rausch, Dietmar Winkler, Lukas Nics, Sazan Rasul, Leo Robert Silberbauer, Murray Bruce Reed, Godber Mathis Godbersen, Jakob Unterholzner, Patricia Handschuh, Gregor Gryglewski, Thomas Mindt, Markus Mitterhauser, Andreas Hahn, Simon Mensah Ametamey, Wolfgang Wadsak, Rupert Lanzenberger, Marcus Hacker
Publikováno v:
EJNMMI Research, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Background The NMDA receptor (NMDAR) plays a key role in the central nervous system, e.g., for synaptic transmission. While synaptic NMDARs are thought to have protective characteristics, activation of extrasynaptic NMDARs might trigger exci
Externí odkaz:
https://doaj.org/article/d21c633daec24b5eae645523e1066d2c
Autor:
Chrysoula Vraka, Matej Murgaš, Lucas Rischka, Barbara Katharina Geist, Rupert Lanzenberger, Gregor Gryglewski, Thomas Zenz, Wolfgang Wadsak, Markus Mitterhauser, Marcus Hacker, Cécile Philippe, Verena Pichler
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Simultaneous characterization of pathologies by multi-tracer positron emission tomography (PET) is among the most promising applications in nuclear medicine. Aim of this work was the simultaneous production of two PET-tracers in one module a
Externí odkaz:
https://doaj.org/article/7488ab9a988048da830bf6bcafc84330
Autor:
Thomas Vanicek, Murray B. Reed, René Seiger, Godber M. Godbersen, Manfred Klöbl, Jakob Unterholzner, Benjamin Spurny-Dworak, Gregor Gryglewski, Patricia Handschuh, Clemens Schmidt, Christoph Kraus, Thomas Stimpfl, Rainer Rupprecht, Siegfried Kasper, Rupert Lanzenberger
Publikováno v:
Therapeutic Advances in Psychopharmacology, Vol 12 (2022)
Background: Serotonergic agents affect brain plasticity and reverse stress-induced dendritic atrophy in key fronto-limbic brain areas associated with learning and memory. Objectives: The aim of this study was to investigate effects of the antidepress
Externí odkaz:
https://doaj.org/article/385104a829a340cc98858c4a57f347b9
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Molecular neuroimaging studies provide mounting evidence that neuroinflammation plays a contributory role in the pathogenesis of major depressive disorder (MDD). This has been the focus of a number of positron emission tomography (PET) studies of the
Externí odkaz:
https://doaj.org/article/263166d2d5d74ce4ad02624a64ecc2f2
Autor:
Gregor Gryglewski, Rupert Lanzenberger, Leo R. Silberbauer, Daniel Pacher, Siegfried Kasper, Rainer Rupprecht, Richard Frey, Pia Baldinger-Melich
Publikováno v:
Brain Stimulation, Vol 14, Iss 4, Pp 927-937 (2021)
Background: Increases in the volume of the amygdala and hippocampus after electroconvulsive therapy (ECT) are among the most robust effects known to the brain-imaging field. Recent advances in the segmentation of substructures of these regions allow
Externí odkaz:
https://doaj.org/article/f46c3529b8c446a89aa05a8f2b252909
Publikováno v:
NeuroImage, Vol 256, Iss , Pp 119214- (2022)
Changes in distribution of associated molecular targets have been reported across several neuropsychiatric disorders. However, the high-resolution topology of most proteins is unknown and simultaneous in vivo measurement in multi-receptor systems is
Externí odkaz:
https://doaj.org/article/9aa315dd677d4682b6a2514d9faa044e
Autor:
Murray Bruce Reed, Manfred Klöbl, Godber Mathis Godbersen, Patricia Anna Handschuh, Vera Ritter, Benjamin Spurny-Dworak, Jakob Unterholzner, Christoph Kraus, Gregor Gryglewski, Dietmar Winkler, René Seiger, Thomas Vanicek, Andreas Hahn, Rupert Lanzenberger
Publikováno v:
NeuroImage, Vol 249, Iss , Pp 118887- (2022)
An essential core function of one's cognitive flexibility is the use of acquired knowledge and skills to adapt to ongoing environmental changes. Animal models have highlighted the influence serotonin has on neuroplasticity. These effects have been pr
Externí odkaz:
https://doaj.org/article/c7997cc188c648e5ad6b01ebe14dc612
Autor:
Manfred Klöbl, René Seiger, Thomas Vanicek, Patricia Handschuh, Murray Bruce Reed, Benjamin Spurny-Dworak, Vera Ritter, Godber Mathis Godbersen, Gregor Gryglewski, Christoph Kraus, Andreas Hahn, Rupert Lanzenberger
Publikováno v:
NeuroImage, Vol 247, Iss , Pp 118829- (2022)
Learning-induced neuroplastic changes, further modulated by content and setting, are mirrored in brain functional connectivity (FC). In animal models, selective serotonin reuptake inhibitors (SSRIs) have been shown to facilitate neuroplasticity. This
Externí odkaz:
https://doaj.org/article/ba181d1eb2fd4480bc1856993017dae6
Autor:
René Seiger, Fabian P. Hammerle, Godber M. Godbersen, Murray B. Reed, Benjamin Spurny-Dworak, Patricia Handschuh, Manfred Klöbl, Jakob Unterholzner, Gregor Gryglewski, Thomas Vanicek, Rupert Lanzenberger
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
The accurate segmentation of in vivo magnetic resonance imaging (MRI) data is a crucial prerequisite for the reliable assessment of disease progression, patient stratification or the establishment of putative imaging biomarkers. This is especially im
Externí odkaz:
https://doaj.org/article/aa37722c997244828de54b616639abb7