Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Gregoire Lauvau"'
Autor:
Koki Ueda, Shu Shien Chin, Noriko Sato, Miyu Nishikawa, Kaori Yasuda, Naoyuki Miyasaka, Betelehem Solomon Bera, Laurent Chorro, Reanna Doña-Termine, Wade R. Koba, David Reynolds, Ulrich G. Steidl, Gregoire Lauvau, John M. Greally, Masako Suzuki
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Vitamin D deficiency is a common deficiency worldwide, particularly among women of reproductive age. During pregnancy, it increases the risk of immune-related diseases in offspring later in life. However, how the body remembers exposure to a
Externí odkaz:
https://doaj.org/article/a6d867e6324a44329f67f7024beb2d83
Publikováno v:
eLife, Vol 11 (2022)
Plasmacytoid dendritic cells (pDCs) are the most potent producer of type I interferon (IFN), but how pDC is primed in vivo is poorly defined. Using a mouse model of severe malaria, we have previously established that upon priming by CD169+ macrophage
Externí odkaz:
https://doaj.org/article/aa653634f5574e27a503e5410d73b946
Autor:
Cristina C. Clement, Angelo D’Alessandro, Sangeetha Thangaswamy, Samantha Chalmers, Raquel Furtado, Sheila Spada, Giada Mondanelli, Federica Ianni, Sarah Gehrke, Marco Gargaro, Giorgia Manni, Luisa Carlota Lopez Cara, Peter Runge, Wanxia Li Tsai, Sinem Karaman, Jorge Arasa, Ruben Fernandez-Rodriguez, Amanda Beck, Antonio Macchiarulo, Massimo Gadina, Cornelia Halin, Francesca Fallarino, Mihaela Skobe, Marc Veldhoen, Simone Moretti, Silvia Formenti, Sandra Demaria, Rajesh K. Soni, Roberta Galarini, Roccaldo Sardella, Gregoire Lauvau, Chaim Putterman, Kari Alitalo, Ursula Grohmann, Laura Santambrogio
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
3-hydroxy-L-kynurenamine (3-HKA) is a metabolite deriving from a lateral pathway of tryptophan catabolism. Here the authors identify 3-HKA as a biogenic amine and show it has anti-inflammatory properties that can protect mice against psoriasis and ne
Externí odkaz:
https://doaj.org/article/95a6bc7fc7a345f08d833daae479ee94
Autor:
Jie Li, Mingkuan Chen, Zilei Liu, Linda Zhang, Brunie H. Felding, Kelley W. Moremen, Gregoire Lauvau, Michael Abadier, Klaus Ley, Peng Wu
Publikováno v:
ACS Central Science, Vol 4, Iss 12, Pp 1633-1641 (2018)
Externí odkaz:
https://doaj.org/article/9fabbafb317e4209b3b5807df4469400
Publikováno v:
eLife. 11
Plasmacytoid dendritic cells (pDCs) are the most potent producer of type I interferon (IFN), but how pDC is primed in vivo is poorly defined. Using a mouse model of severe malaria, we have previously established that upon priming by CD169+ macrophage
Autor:
Marie Boutet, Piril Erler, Kenta Nishitani, Nicole Couturier, Zheng Zhang, Emeline Barbieux, Erik Guillen, Masako Suzuki, Gregoire Lauvau, Wenjun Guo
Understanding how specific cancer mutations modulate the tumor microenvironment is essential for developing new precision cancer therapies. The histone methyltransferase MLL3 is a tumor suppressor that is frequently mutated together with p53 and PI3-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29e228b4bf513e5349279070c4db8abe
https://doi.org/10.1101/2022.10.02.510540
https://doi.org/10.1101/2022.10.02.510540
Autor:
Wenhao Yu, Xinlu Zhao, Abubakar S. Jalloh, Yingying Zhao, Brandon Dinner, Yang Yang, Shian Ouyang, Yachao Li, Tian Tian, Zihan Zhao, Rong Yang, Mingkuan Chen, Gregoire Lauvau, Zijian Guo, Peng Wu, Jie P. Li
Despite the rich information of a cell’s physiological state encoded in the dynamic changes of cell-surface glycans, methods of capturing glycosylation states at the single-cell level are quite limited. Here we report a chemoenzymatic single-cell N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::231e862ad8d135f15be855c68667cdfa
https://doi.org/10.1101/2022.09.01.506123
https://doi.org/10.1101/2022.09.01.506123
Autor:
Erik Guillen, Shu Shien Chin, Laurent Chorro, Sooraj Achar, Karina Ng, Susanen Oberle, Francesca Alfei, Dietmar Zehn, Gregoire Altan-Bonnet, Fabien Delahaye, Gregoire Lauvau
Publikováno v:
The Journal of Immunology. 208:57.10-57.10
Priming of naïve CD8+ T cells requires three signals: 1) cognate antigen, 2) co-stimulation, and 3) cytokines. These signals orchestrate CD8+ T cell differentiation. Particularly, strong T cell receptor (TCR) signals induce a more robust effector re
Autor:
Shajo, Kunnath-Velayudhan, Michael F, Goldberg, Neeraj K, Saini, Tony W, Ng, Pooja, Arora, Christopher T, Johndrow, Noemi Alejandra, Saavedra-Avila, Alison J, Johnson, Jiayong, Xu, John, Kim, Nazanin, Khajoueinejad, Christopher D, Petro, Betsy C, Herold, Gregoire, Lauvau, John, Chan, William R, Jacobs, Steven A, Porcelli
Publikováno v:
ImmunoHorizons
During Ag priming, naive CD4+ T cells differentiate into subsets with distinct patterns of cytokine expression that dictate to a major extent their functional roles in immune responses. We identified a subset of CD4+ T cells defined by secretion of I