Zobrazeno 1 - 10
of 304
pro vyhledávání: '"Gregg T Beckham"'
Autor:
Anton A. Stepnov, Esteban Lopez-Tavera, Ross Klauer, Clarissa L. Lincoln, Ravindra R. Chowreddy, Gregg T. Beckham, Vincent G. H. Eijsink, Kevin Solomon, Mark Blenner, Gustav Vaaje-Kolstad
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Biocatalytic degradation of non-hydrolyzable plastics is a rapidly growing field of research, driven by the global accumulation of waste. Enzymes capable of cleaving the carbon-carbon bonds in synthetic polymers are highly sought-after as th
Externí odkaz:
https://doaj.org/article/4fac7be2349d4d5caf23eb63391071b2
Autor:
Brenna Norton-Baker, Mackenzie C. R. Denton, Natasha P. Murphy, Benjamin Fram, Samuel Lim, Erika Erickson, Nicholas P. Gauthier, Gregg T. Beckham
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract As genomic databases expand and artificial intelligence tools advance, there is a growing demand for efficient characterization of large numbers of proteins. To this end, here we describe a generalizable pipeline for high-throughput protein
Externí odkaz:
https://doaj.org/article/663421856240400c9acd2223616ba2ec
Autor:
Jacob K. Kenny, Sasha R. Neefe, David G. Brandner, Michael L. Stone, Renee M. Happs, Ivan Kumaniaev, William P. Mounfield, Anne E. Harman-Ware, Katrien M. Devos, Thomas H. Pendergast, J. Will Medlin, Yuriy Román-Leshkov, Gregg T. Beckham
Publikováno v:
JACS Au, Vol 4, Iss 6, Pp 2173-2187 (2024)
Externí odkaz:
https://doaj.org/article/31fd14f697a542b5925277fcc76396f9
Autor:
Tucker Burgin, Benjamin C. Pollard, Brandon C. Knott, Heather B. Mayes, Michael F. Crowley, John E. McGeehan, Gregg T. Beckham, H. Lee Woodcock
Publikováno v:
Communications Chemistry, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract Polyethylene terephthalate (PET), the most abundantly produced polyester plastic, can be depolymerized by the Ideonella sakaiensis PETase enzyme. Based on multiple PETase crystal structures, the reaction has been proposed to proceed via a tw
Externí odkaz:
https://doaj.org/article/67fd36bc8cfd4014933a9bb520abcb5b
Autor:
Elizabeth L. Bell, Gloria Rosetto, Morgan A. Ingraham, Kelsey J. Ramirez, Clarissa Lincoln, Ryan W. Clarke, Japheth E. Gado, Jacob L. Lilly, Katarzyna H. Kucharzyk, Erika Erickson, Gregg T. Beckham
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Successes in biocatalytic polyester recycling have raised the possibility of deconstructing alternative polymers enzymatically, with polyamide (PA) being a logical target due to the array of amide-cleaving enzymes present in nature. Here, we
Externí odkaz:
https://doaj.org/article/f80505c5d5fe4ba6bcc10a57e9028c2d
Autor:
Chad T. Palumbo, Nina X. Gu, Alissa C. Bleem, Kevin P. Sullivan, Rui Katahira, Lisa M. Stanley, Jacob K. Kenny, Morgan A. Ingraham, Kelsey J. Ramirez, Stefan J. Haugen, Caroline R. Amendola, Shannon S. Stahl, Gregg T. Beckham
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Efforts to produce aromatic monomers through catalytic lignin depolymerization have historically focused on aryl–ether bond cleavage. A large fraction of aromatic monomers in lignin, however, are linked by various carbon–carbon (C–C) b
Externí odkaz:
https://doaj.org/article/4af11bcfb84a4cdd8637b29f91da4cef
Autor:
Deanne W Sammond, Christina M Payne, Roman Brunecky, Michael E Himmel, Michael F Crowley, Gregg T Beckham
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e48615 (2012)
Cellulase enzymes deconstruct cellulose to glucose, and are often comprised of glycosylated linkers connecting glycoside hydrolases (GHs) to carbohydrate-binding modules (CBMs). Although linker modifications can alter cellulase activity, the function
Externí odkaz:
https://doaj.org/article/9f49c6f6c3294964a10f4b2fd85c9b55
Autor:
Andrew J. Borchert, Alissa C. Bleem, Hyun Gyu Lim, Kevin Rychel, Keven D. Dooley, Zoe A. Kellermyer, Tracy L. Hodges, Bernhard O. Palsson, Gregg T. Beckham
Publikováno v:
mSystems, Vol 9, Iss 3 (2024)
ABSTRACTThere is growing interest in engineering Pseudomonas putida KT2440 as a microbial chassis for the conversion of renewable and waste-based feedstocks, and metabolic engineering of P. putida relies on the understanding of the functional relatio
Externí odkaz:
https://doaj.org/article/ee100d70f1d0471c822a1d1d800281c8
Autor:
Nina X. Gu, Chad T. Palumbo, Alissa C. Bleem, Kevin P. Sullivan, Stefan J. Haugen, Sean P. Woodworth, Kelsey J. Ramirez, Jacob K. Kenny, Lisa D. Stanley, Rui Katahira, Shannon S. Stahl, Gregg T. Beckham
Publikováno v:
ACS Central Science, Vol 9, Iss 12, Pp 2277-2285 (2023)
Externí odkaz:
https://doaj.org/article/c8afedc849cb4cc9af67fc9a91f79ecc
Autor:
Erika Erickson, Japheth E. Gado, Luisana Avilán, Felicia Bratti, Richard K. Brizendine, Paul A. Cox, Raj Gill, Rosie Graham, Dong-Jin Kim, Gerhard König, William E. Michener, Saroj Poudel, Kelsey J. Ramirez, Thomas J. Shakespeare, Michael Zahn, Eric S. Boyd, Christina M. Payne, Jennifer L. DuBois, Andrew R. Pickford, Gregg T. Beckham, John E. McGeehan
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Enzymes have potential for recycling plastics such as PET, a polyester used in textiles and single-use packaging. Here, the authors identify and characterize additional PET-active biocatalysts and expand the number and diversity of thermotolerant sca
Externí odkaz:
https://doaj.org/article/948513aa5c164d4e92b945bb6ce6fa3b