Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Gregg Sobocinski"'
Autor:
Mudher Albassam, Jonathan Chupka, XinWen Yu, Yunling Song, J. Eric McDuffie, Gregg Sobocinski
Publikováno v:
Cardiovascular Toxicology. 6:25-38
The objective of this study was to characterize acute coronary artery injury evoked by the endothelin A receptor (ETAR) antagonist, CI-1034. Male dogs (n = 5) were intravenously administered CI-1034 at 120 mg/kg for 4 d. Control animals (n = 3) recei
Axonopathy, tau abnormalities, and dyskinesia, but no neurofibrillary tangles in p25-transgenic mice
Autor:
Rathna Nath, William J. Lipinski, Lary C. Walker, Michael J. Callahan, Robert N. Booher, Amy Pack, Gregg Sobocinski, Kevin K.W. Wang, Feng Bian
Publikováno v:
The Journal of Comparative Neurology. 446:257-266
Neurofibrillary tangles, one of the pathologic hallmarks of Alzheimer's disease (AD), are composed of abnormally polymerized tau protein. The hyperphosphorylation of tau alters its normal cellular function and is thought to promote the formation of n
Autor:
J. F. Reindel, Gregg Sobocinski, Alexander W. Gough, Gary D. Pilcher, Walter F. Bobrowski, Felix A. de la Iglesia
Publikováno v:
Toxicologic Pathology. 29:159-173
Epidermal growth factor (EGF) effects have been explored extensively in vivo in rodents, but little is known about trophic responses in nonhuman primates. A previous publication reports the hyperplastic epithelial/parenchymal changes noted in the dig
Autor:
Mark C. Kowala, Brandy Morenko, Terry C. Major, Steven Madore, Serguei Liachenko, Shantanu Dhamija, Nicole W. Black, Carlin Okerberg, Paula Tinholt, Gregg Sobocinski
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 325(3)
Among the L-type calcium channel blockers (CCBs), particularly dihydropyridines like nifedipine [1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic acid dimethyl ester], a common adverse effect is vasodilatory edema. Newer CCBs, such
Autor:
Mark D. Rolsma, Walter F. Bobrowski, Alan L. Metz, Leslie A. Obert, Douglas M. Altrogge, Robert W. Dunstan, Gregg Sobocinski
Publikováno v:
Toxicologic pathology. 35(5)
Hepatocellular vacuolation can be a diagnostic challenge since cytoplasmic accumulations of various substances (lipid, water, phospholipids, glycogen, and plasma) can have a similar morphology. Cytoplasmic accumulation of phospholipids following admi
Autor:
J. Eric McDuffie, Amy Bowman, Mudher Albassam, Eric W Olle, Gregg Sobocinski, Walter F. Bobrowski, Jonathan Chupka
Publikováno v:
Cytokine. 32(5)
Changes in circulating cytokines might serve as predictors of compound-evoked inflammatory responses. CD-1 mice were treated with lipopolysaccharide (LPS; 0.2 ml of 0.25 mg/ml, intraperitoneal) for subsequent expression measurement of plasma cytokine
Autor:
J. Eric McDuffie, XinWen Yu, Gregg Sobocinski, Yunling Song, Jonathan Chupka, Mudher Albassam
Publikováno v:
Cardiovascular Toxicology; Spring2006, Vol. 6 Issue 1, p25-38, 14p