Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Gregg Silverman"'
Autor:
Ahmed S. Elshikha, Yong Ge, Josephine Brown, Nathalie Kanda, Mojgan Zadeh, Georges Abboud, Seung-Chul Choi, Gregg Silverman, Timothy J. Garrett, William L. Clapp, Mansour Mohamadzadeh, Laurence Morel
Publikováno v:
iScience, Vol 26, Iss 7, Pp 107122- (2023)
Summary: Gut dysbiosis has been associated with lupus pathogenesis, and fecal microbiota transfers (FMT) from lupus-prone mice shown to induce autoimmune activation into healthy mice. The immune cells of lupus patients exhibit an increased glucose me
Externí odkaz:
https://doaj.org/article/229a7a042b954b65b4b97ba2cac53849
Tonic interferon restricts pathogenic IL-17-driven inflammatory disease via balancing the microbiome
Autor:
Isabelle J Marié, Lara Brambilla, Doua Azzouz, Ze Chen, Gisele V Baracho, Azlann Arnett, Haiyan S Li, Weiguo Liu, Luisa Cimmino, Pratip Chattopadhyay, Gregg Silverman, Stephanie S Watowich, Bernard Khor, David E Levy
Publikováno v:
eLife, Vol 10 (2021)
Maintenance of immune homeostasis involves a synergistic relationship between the host and the microbiome. Canonical interferon (IFN) signaling controls responses to acute microbial infection, through engagement of the STAT1 transcription factor. How
Externí odkaz:
https://doaj.org/article/982a4035ae764dbdbb7abc2f4d9fe2a7
Publikováno v:
Animal Models and Experimental Medicine, Vol 2, Iss 2, Pp 98-106 (2019)
Abstract Background Patients with rheumatoid arthritis (RA) have an increased risk for cardiovascular disease. We examined the effect of gut microbiota in a mouse model of RA that develops atherosclerosis. Methods We created three groups of K/BxN fem
Externí odkaz:
https://doaj.org/article/58da4cb296604bc1a4495470c742f4ea
Autor:
Yi Koh, Jennifer Gahan, Kathren Fink, Gregg Silverman, Bruce Beutler, David Nemazee, Argyrios Theofilopoulos, Dwight Kono
Publikováno v:
The Journal of Immunology. 186:44.29-44.29
SLE is associated with a diversity of autoAbs, of which some are relatively specific for SLE, whereas others are also found in other autoimmune diseases. Nucleic acid sensing-TLRs (TLR3, 7-9; NA-TLRs) through the engagement of NA-containing material