Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Gregg P. Solar"'
Autor:
Gregg P. Solar, Ajay K. Malik, Daniel Eric Sherman, Xiao Huan Liang, James C. Marsters, Hans-Peter Gerber, Gloria Meng, Kyu Hong, Napoleone Ferrara
Publikováno v:
Nature. 417:954-958
Vascular endothelial growth factor (VEGF) is a principal regulator of blood vessel formation and haematopoiesis, but the mechanisms by which VEGF differentially regulates these processes have been elusive. Here we describe a regulatory loop by which
Publikováno v:
Stem Cells. 16:31-36
Thrombopoietin is a lineage-dominant cytokine involved primarily in the control of platelet production. The physiological importance of thrombopoietin (TPO) in the regulation of megakaryocyte and platelet production was demonstrated by the production
Publikováno v:
Blood. 89:3624-3635
The microenvironment is a key regulator of hematopoietic stem cells (HSCs) and is a likely source of extracellular factors that control stem cell fate. A better understanding of these microenvironmental factors may come from investigations of develop
Autor:
G. Roger Thomas, Jean Q. Yuan, Brian D. Bennett, Gregg P. Solar, Joanne Mathias, William Matthews
Publikováno v:
Current Biology. 6:1170-1180
Background Hematopoiesis entails the production of multiple blood cell lineages throughout the lifespan of the organism. This is accomplished by the regulated expansion and differentiation of hematopoietic precursors that originate from self-renewing