Zobrazeno 1 - 10
of 1 652
pro vyhledávání: '"Gregg L, Semenza"'
Autor:
Ahmed, Farooq
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2010 Aug . 107(33), 14521-14523.
Externí odkaz:
https://www.jstor.org/stable/25708940
Autor:
Yajing Lyu, Yongkang Yang, Varen Talwar, Haiquan Lu, Chelsey Chen, Shaima Salman, Elizabeth E. Wicks, Tina Yi-Ting Huang, Daiana Drehmer, Yufeng Wang, Qiaozhu Zuo, Emmanuel Datan, Walter Jackson, III, Dominic Dordai, Ru Wang, Gregg L. Semenza
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 113972- (2024)
Summary: Hypoxia-inducible factor 1 (HIF-1) is a transcriptional activator that mediates cellular adaptation to decreased oxygen availability. HIF-1 recruits chromatin-modifying enzymes leading to changes in histone acetylation, citrullination, and m
Externí odkaz:
https://doaj.org/article/81c1beb3ca954c18aaff5e6ff94c9e4a
Akademický článek
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Akademický článek
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Autor:
Schwarz, Edward, Firestein, Gary S.
Publikováno v:
The Quarterly Review of Biology, 2000 Sep 01. 75(3), 310-311.
Externí odkaz:
https://www.jstor.org/stable/2665210
Autor:
Jing Zhang, Deepti Sharma, Aumreetam Dinabandhu, Jaron Sanchez, Brooks Applewhite, Kathleen Jee, Monika Deshpande, Miguel Flores-Bellver, Ming-Wen Hu, Chuanyu Guo, Shaima Salman, Yousang Hwang, Nicole M. Anders, Michelle A. Rudek, Jiang Qian, M. Valeria Canto-Soler, Gregg L. Semenza, Silvia Montaner, Akrit Sodhi
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 13 (2023)
Many patients with diabetic eye disease respond inadequately to anti-VEGF therapies, implicating additional vasoactive mediators in its pathogenesis. We demonstrate that levels of angiogenic proteins regulated by HIF-1 and -2 remain elevated in the e
Externí odkaz:
https://doaj.org/article/208f02b363f54dcab967e446a3a95992
Autor:
Josef T. Prchal, Gregg L. Semenza
Publikováno v:
Haematologica, Vol 108, Iss 10 (2023)
Externí odkaz:
https://doaj.org/article/32a21dfa1b554a05950d03b699d8ee31
Autor:
Farooq Ahmed
Publikováno v:
Proceedings of the National Academy of Sciences. 107:14521-14523
“Without oxygen for 5 minutes, you're dead,” sums up Gregg L. Semenza, professor of pediatrics at The Johns Hopkins University (Baltimore). He has spent his career using genetics and molecular biology to study various aspects of how living system
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f56bdc3a05195bb8c94698985399524
https://doi.org/10.1073/pnas.1009481107
https://doi.org/10.1073/pnas.1009481107
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Hypoxia-inducible factor-1 (HIF-1) is a transcription factor that modulates target gene expression in response to changes in oxygen availability. Here the authors show that HIF-1 forms a complex with TRIM28 and DNA-dependent protein kinase (DNA-PK) t
Externí odkaz:
https://doaj.org/article/34b58a895ed248ba90fef65625529862
Autor:
Qiaozhu Zuo, Yongkang Yang, Yajing Lyu, Chen Yang, Chelsey Chen, Shaima Salman, Tina Yi-Ting Huang, Elizabeth E. Wicks, Walter Jackson, III, Emmanuel Datan, Wenxin Qin, Gregg L. Semenza
Publikováno v:
Cell Reports, Vol 42, Iss 3, Pp 112164- (2023)
Summary: Intratumoral hypoxia is a microenvironmental feature that promotes breast cancer progression and is associated with cancer mortality. Plexin B3 (PLXNB3) is highly expressed in estrogen receptor-negative breast cancer, but the underlying mech
Externí odkaz:
https://doaj.org/article/33aaf8ed82ef405fa617b1722f2239c3