Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Greg W. Butler"'
Autor:
Ruben Crespo-Diaz, Atta Behfar, Greg W. Butler, Douglas J. Padley, Michael G. Sarr, Jozef Bartunek, Allan B. Dietz, Andre Terzic
Publikováno v:
Cell Transplantation, Vol 20 (2011)
With favorable regenerative and immunotolerant profiles, patient-derived human mesenchymal stem cells (hMSCs) are increasingly considered in cell therapy. Derived from bone marrow (BM) and standardized with culture in fetal bovine serum (FBS), transl
Externí odkaz:
https://doaj.org/article/c3aba8b4b39241949474f38cf7c4d958
Autor:
Amy L. Lightner, Allan B. Dietz, Joel G. Fletcher, William A. Faubion, Eric J. Dozois, Greg W. Butler, Jessica Friton
Publikováno v:
Inflammatory Bowel Diseases. 26:670-677
Background Crohn’s rectovaginal fistulizing disease remains notoriously difficult to treat. A phase I clinical trial to evaluate the safety and feasibility of a novel protocol using a mesenchymal stem cell (MSC)–coated Gore Bio-A fistula plug for
Autor:
Greg W. Butler, Jessica Friton, Eric J. Dozois, Heidi K. Chua, Allan B. Dietz, Kellie L. Mathis, Amy L. Lightner, Scott R. Kelley, William A. Faubion, Joel G. Fletcher
Publikováno v:
Diseases of the Colon & Rectum. 62:615-622
Management of transsphincteric cryptoglandular fistulas remains a challenging problem and the optimal surgical approach remains elusive. Mesenchymal stem cells, increasingly being utilized for perianal Crohn's disease, offer a novel therapy to treat
Autor:
Anthony J. Windebank, Allan B. Dietz, Eric J. Sorenson, Nathan P. Staff, Greg W. Butler, Mark E. Jentoft, Jonathan M. Morris, Dennis A. Gastineau, Nicolas N. Madigan
Publikováno v:
Neurology. 87:2230-2234
Objective:To determine the safety of intrathecal autologous adipose-derived mesenchymal stromal cell treatment for amyotrophic lateral sclerosis (ALS).Methods:Participants with ALS were enrolled and treated in this phase I dose-escalation safety tria
Autor:
Eapen K. Jacob, Amel Dudakovic, A. J. Van Wijnen, Peggy A. Bulur, A. Dietz, A.A. Krull, Greg W. Butler
Publikováno v:
Cytotherapy. 22:S91
Background & Aim Background & Aim: The plasticity of mesenchymal stromal cells (MSCs) in responding to damage by promoting immunosuppression and tissue regeneration has been leveraged to treat conditions such as spinal cord injury. But can MSC plasti
Autor:
Douglas J. Padley, Nathan P. Staff, Anthony J. Windebank, Allan B. Dietz, Jarred J. Nesbitt, Bingkun K. Chen, Joseph E. Parisi, Greg W. Butler, Andrew M. Knight
Publikováno v:
Transfusion. 55:1013-1020
Background There are no effective treatments that slow the progression of neurodegenerative diseases. A major challenge of treatment in neurodegenerative diseases is appropriate delivery of pharmaceuticals into the cerebrospinal fluid (CSF) of affect
Autor:
Marina Ramirez-Alvarado, Peggy A. Bulur, Yi Lin, Keely R. Redhage, Christopher J. Dick, Marta Marin-Argany, Greg W. Butler, Jonathan S. Wall, Luis M. Blancas-Mejia, Benjamin J. Madden, Allan B. Dietz, Angela Williams, Michael C. Deeds
Background aims Light chain (AL) amyloidosis is a protein misfolding disease characterized by extracellular deposition of immunoglobulin light chains (LC) as amyloid fibrils. Patients with LC amyloid involvement of the heart have the worst morbidity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05bc1d3e3dee95db703ddccfca94865e
https://europepmc.org/articles/PMC6456258/
https://europepmc.org/articles/PMC6456258/
Autor:
Allan B. Dietz, Anthony J. Windebank, Adeel S. Zubair, Greg W. Butler, Michael P. Gustafson, Nathan P. Staff, Svetlana Bornschlegl, Mary Maas, Mohamed Kazamel, Dennis A. Gastineau
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 7, p e0182002 (2017)
PLoS ONE, Vol 12, Iss 7, p e0182002 (2017)
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with a median lifespan of 2-3 years after diagnosis. There are few meaningful treatments that alter progression in this disease. Preclinical and clinical studies have demonstrat
Autor:
Stephen D. Cassivi, Allan B. Dietz, Zachary T. Resch, Dennis A. Wigle, Brian T. Carlsen, William A. Faubion, Greg W. Butler, Darcie J. Radel, Johnathon M. Aho, Timothy J. Nelson, Mathew Thomas
Publikováno v:
Stem Cells Translational Medicine
This is the first-in-human application of an autologous mesenchymal stem cell (MSC)-seeded matrix graft to repair a multiply recurrent postpneumonectomy bronchopleural fistula (BPF). Adipose-derived MSCs were isolated from patient abdominal adipose t
Autor:
Sarah F. Paternoster, Stephanie R. Fink, Greg W. Butler, Louis Letendre, A Tefferi, Mark R. Litzow, Stanimir Vuk-Pavlović, Dennis A. Gastineau, Douglas J. Padley, Peggy A. Bulur, Allan B. Dietz, Antje Hoering
Publikováno v:
Cytotherapy. 8:290-298
We conducted a phase I clinical immunotherapy trial of CML to evaluate the safety of a clinical-grade leukemic DC product standardized for purity and mature phenotype.We injected autologous DC into patients in late chronic or accelerated phases of CM