Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Greg W. Kilby"'
Autor:
Elena N. Pugacheva, Neal Shah, Sricharan Mahavadi, Greg W. Kilby, Pamela S. Cantrell, Callee M. Walsh, Ginger P. Layne, Hannah W. Hazard, Sijin Wen, Mohamad A. Salkeni, Ryan H. Livengood, Kristina Marinak, Matthew B. Smolkin, Fatimah Matalkah, Yuriy V. Loskutov, Brandon C. Jones, Ryan J. Ice, Anna A. Kiseleva, Varvara K. Kozyreva
Representative movie of individual MDA-MB-231LN cells treated with Vehicle, MLN8237, eribulin, or MLN8237/eribulin combination, suspended in collagen, and manually tracked over the course of 23 hours toward the serum chemoattractant-containing reserv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7997dae0d7d254369c9e07211599f4ae
https://doi.org/10.1158/1535-7163.22508218
https://doi.org/10.1158/1535-7163.22508218
Autor:
Elena N. Pugacheva, Neal Shah, Sricharan Mahavadi, Greg W. Kilby, Pamela S. Cantrell, Callee M. Walsh, Ginger P. Layne, Hannah W. Hazard, Sijin Wen, Mohamad A. Salkeni, Ryan H. Livengood, Kristina Marinak, Matthew B. Smolkin, Fatimah Matalkah, Yuriy V. Loskutov, Brandon C. Jones, Ryan J. Ice, Anna A. Kiseleva, Varvara K. Kozyreva
File contains Supplementary figures: Figure 1: AUKRA analysis in TNBC cell lines in response to drug treatments. Additional TNBC migration/invasion analysis. Figure 2. Representative FACS analysis flow charts of TNBCs undergoing apoptosis. Figure 3.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::213ece0ad103527f71ce5fc1158f36c3
https://doi.org/10.1158/1535-7163.22508212
https://doi.org/10.1158/1535-7163.22508212
Autor:
Elena N. Pugacheva, Neal Shah, Sricharan Mahavadi, Greg W. Kilby, Pamela S. Cantrell, Callee M. Walsh, Ginger P. Layne, Hannah W. Hazard, Sijin Wen, Mohamad A. Salkeni, Ryan H. Livengood, Kristina Marinak, Matthew B. Smolkin, Fatimah Matalkah, Yuriy V. Loskutov, Brandon C. Jones, Ryan J. Ice, Anna A. Kiseleva, Varvara K. Kozyreva
File contains detailed information on Supplementary video files.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::054dc92f0888cd25c16c1d88696ce2b6
https://doi.org/10.1158/1535-7163.22508203.v1
https://doi.org/10.1158/1535-7163.22508203.v1
Autor:
Elena N. Pugacheva, Neal Shah, Sricharan Mahavadi, Greg W. Kilby, Pamela S. Cantrell, Callee M. Walsh, Ginger P. Layne, Hannah W. Hazard, Sijin Wen, Mohamad A. Salkeni, Ryan H. Livengood, Kristina Marinak, Matthew B. Smolkin, Fatimah Matalkah, Yuriy V. Loskutov, Brandon C. Jones, Ryan J. Ice, Anna A. Kiseleva, Varvara K. Kozyreva
Table contains diagnostics/characterization of original and patient-derived models.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::565eebabc18c4342388042be78b893bd
https://doi.org/10.1158/1535-7163.22508206.v1
https://doi.org/10.1158/1535-7163.22508206.v1
Autor:
Elena N. Pugacheva, Neal Shah, Sricharan Mahavadi, Greg W. Kilby, Pamela S. Cantrell, Callee M. Walsh, Ginger P. Layne, Hannah W. Hazard, Sijin Wen, Mohamad A. Salkeni, Ryan H. Livengood, Kristina Marinak, Matthew B. Smolkin, Fatimah Matalkah, Yuriy V. Loskutov, Brandon C. Jones, Ryan J. Ice, Anna A. Kiseleva, Varvara K. Kozyreva
File contains detailed protocols and information on used reagents to facilitate reproducible of the presented data.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ea168f6f954b9f94deb3cf9b8f1796d
https://doi.org/10.1158/1535-7163.22508209.v1
https://doi.org/10.1158/1535-7163.22508209.v1
Autor:
Elena N. Pugacheva, Neal Shah, Sricharan Mahavadi, Greg W. Kilby, Pamela S. Cantrell, Callee M. Walsh, Ginger P. Layne, Hannah W. Hazard, Sijin Wen, Mohamad A. Salkeni, Ryan H. Livengood, Kristina Marinak, Matthew B. Smolkin, Fatimah Matalkah, Yuriy V. Loskutov, Brandon C. Jones, Ryan J. Ice, Anna A. Kiseleva, Varvara K. Kozyreva
Representative movie of individual BT-549 cells treated with Vehicle, MLN8237, eribulin, or MLN8237/eribulin combination, suspended in collagen, and manually tracked over the course of 23 hours toward the serum chemoattractant-containing reservoir (l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52713904b6c69e80180610b1b92f32db
https://doi.org/10.1158/1535-7163.22508215
https://doi.org/10.1158/1535-7163.22508215
Autor:
Matthew B. Smolkin, Sijin Wen, Mohamad Adham Salkeni, Neal Shah, Ginger Layne, Elena N. Pugacheva, Hannah Hazard, Ryan H. Livengood, Fatimah Matalkah, Greg W. Kilby, Kristina M. Marinak, Ryan J. Ice, Pamela S. Cantrell, Varvara K. Kozyreva, Callee M. Walsh, Sricharan Mahavadi, Anna A. Kiseleva, Brandon C. Jones, Yuriy Loskutov
Publikováno v:
Molecular Cancer Therapeutics. 15:1809-1822
Recent findings suggest that the inhibition of Aurora A (AURKA) kinase may offer a novel treatment strategy against metastatic cancers. In the current study, we determined the effects of AURKA inhibition by the small molecule inhibitor MLN8237 both a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14110c7f9d4d075a7a21fce55a9cbe03
https://doi.org/10.1158/1535-7163.mct-15-0688
https://doi.org/10.1158/1535-7163.mct-15-0688
Autor:
J. David Baker, Tracy I. Stevenson, Douglas A. Gage, Sam Donohoe, Erin E. Brzezinski, Mark P. Molloy, David R. Goodlett, Greg W. Kilby
Publikováno v:
PROTEOMICS. 5:1204-1208
Strategies employing non-gel based methods for quantitative proteomic profiling such as isotope coded affinity tags coupled with mass spectrometry (ICAT-MS) are gaining attention as alternatives to two-dimensional gel electrophoresis (2-DE). We have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9e97b5cc183046e3a87fa38d085386a
https://doi.org/10.1002/pmic.200400994
https://doi.org/10.1002/pmic.200400994
Autor:
Greg W. Kilby, Prasad S. Adusumilli, Hua-Jun Wu, Charlotte E. Lee, Andre L. Moreira, Franziska Michor, Robert J. Downey, Erin H. Seeley
Publikováno v:
Journal of Thoracic Oncology. 12:S800
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da242fb063c85cb62500f49eb5c3805c
https://doi.org/10.1016/j.jtho.2016.11.1078
https://doi.org/10.1016/j.jtho.2016.11.1078
Autor:
Greg W. Kilby, Tracy I. Stevenson, Beth McGee, Joseph Macri, John N. Thomas, Ping Du, Stephen T. Rapundalo
Publikováno v:
Electrophoresis. 21:1685-1693
We evaluated the use of the alkyaryl amidosulfobetaine zwitterionic detergent, designated as C8psi, to facilitate the solubilization of cardiac subcellular, membrane-associated proteins. Hearts from 7-week-old male Sprague-Dawley rats were isolated,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a43655e52e9dbf390b2863ffe7fe4294
https://doi.org/10.1002/(sici)1522-2683(20000501)21:9<1685::aid-elps1685>3.0.co
https://doi.org/10.1002/(sici)1522-2683(20000501)21:9<1685::aid-elps1685>3.0.co