Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Greg T. Macleod"'
Autor:
Rebekah E. Mahoney, Joel M. Rawson, Jon Gelfond, Holly Davison, Tabita Kreko, Benjamin A. Eaton, Leo Chang, Alex Bokov, Greg T. Macleod
Publikováno v:
Aging Cell. 11:418-427
Synaptic dysfunction is considered the primary substrate for the functional declines observed within the nervous system during age-related neurodegenerative disease. Dietary restriction (DR), which extends lifespan in numerous species, has been shown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0050378dfc857e31e23a76df0dc0297
https://doi.org/10.1111/j.1474-9726.2012.00799.x
https://doi.org/10.1111/j.1474-9726.2012.00799.x
Autor:
Sarvari Panchumarthi, Miriam Schoenfield, Milton P. Charlton, Harold L. Atwood, Leo Marin, Andrea Wellington, Fangle Hu, Xiufang Guo, Konrad E. Zinsmaier, Greg T. Macleod
Publikováno v:
Neuron. 47(3):379-393
SummaryWe have identified EMS-induced mutations in Drosophila Miro (dMiro), an atypical mitochondrial GTPase that is orthologous to human Miro (hMiro). Mutant dmiro animals exhibit defects in locomotion and die prematurely. Mitochondria in dmiro muta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56b5c786b4b5ac4b4787149a80fac417
Publikováno v:
The Journal of Neuroscience. 24:3964-3973
TheN-ethylmaleimide-sensitive factor (NSF) and soluble NSF attachment protein (SNAP) are cytosolic factors that promote vesicle fusion with a target membrane in both the constitutive and regulated secretory pathways. NSF and SNAP are thought to funct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21b75b81cfaf72d799108ca517182ae6
https://doi.org/10.1523/jneurosci.5259-03.2004
https://doi.org/10.1523/jneurosci.5259-03.2004
Publikováno v:
The Journal of Neuroscience. 21:2380-2392
A study has been made of the formation and regression of synapses with respect to Schwann cells at the ends of motor nerve terminal branches in mature toad (Bufo marinus) muscle. Synapse formation and regression, as inferred from the appearance and l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6277444e05ed5625b2ec8b85d03ae0da
https://doi.org/10.1523/jneurosci.21-07-02380.2001
https://doi.org/10.1523/jneurosci.21-07-02380.2001
Autor:
Joel M, Rawson, Tabita, Kreko, Holly, Davison, Rebekah, Mahoney, Alex, Bokov, Leo, Chang, Jon, Gelfond, Greg T, Macleod, Benjamin A, Eaton
Publikováno v:
Aging cell. 11(3)
Synaptic dysfunction is considered the primary substrate for the functional declines observed within the nervous system during age-related neurodegenerative disease. Dietary restriction (DR), which extends lifespan in numerous species, has been shown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::998a73039abfbb5e5dd41b02ca637b57
https://pubmed.ncbi.nlm.nih.gov/22268717
https://pubmed.ncbi.nlm.nih.gov/22268717
Autor:
Greg T. Macleod, Fangle Hu, Kathryn Louie, Andrea Wellington, Sarvari Panchumarthi, Gary J. Russo, Konrad E. Zinsmaier
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 29(17)
Microtubule-based transport of mitochondria into dendrites and axons is vital for sustaining neuronal function. Transport along microtubule tracks proceeds in a series of plus and minus end-directed movements that are facilitated by kinesin and dynei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92d16ca276c8d9bc56f02cfec03612b6
https://pubmed.ncbi.nlm.nih.gov/19403812
https://pubmed.ncbi.nlm.nih.gov/19403812
Membrane-bound organelles such as mitochondria and the endoplasmic reticulum play an important role in neuronal Ca2+homeostasis. Synaptic vesicles (SVs), the organelles responsible for exocytosis of neurotransmitters, occupy more of the volume of pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e80239fda66121296451dbce7c946636
https://europepmc.org/articles/PMC6729477/
https://europepmc.org/articles/PMC6729477/
