Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Greg Szot"'
Autor:
Qiang Liu, Pankaj Garg, Burcu Hasdemir, Linya Wang, Emily Tuscano, Emily Sever, Erica Keane, Ana G Lujan Hernandez, Tom Z. Yuan, Eric Kwan, Joyce Lai, Greg Szot, Sreenivasan Paruthiyil, Fumiko Axelrod, Aaron K. Sato
Publikováno v:
mAbs, Vol 13, Iss 1 (2021)
G protein-coupled receptors (GPCRs) are a group of seven-transmembrane receptor proteins that have proven to be successful drug targets. Antibodies are becoming an increasingly promising modality to target these receptors due to their unique properti
Externí odkaz:
https://doaj.org/article/4eac4f5c52cc4fb2ab2059e4e0a65757
Autor:
Greg Szot, Vinh Son Nguyen, Andrew M. Posselt, Peter G. Stock, Kristina Johnson, Steven A. Wisel, Joan McElroy, James M. Gardner, Umesh Mashirani, Qizhi Tang
Publikováno v:
Transplantation. 102:S374
Autor:
Greg Szot, Jianqin Ye, Jeffrey A. Bluestone, Qizhi Tang, Mingying Bi, Kammi J. Henriksen, Mark Bonyhadi, Erik B. Finger, Hugh O. McDevitt, Emma L. Masteller
Publikováno v:
The Journal of Experimental Medicine
The low number of CD4+ CD25+ regulatory T cells (Tregs), their anergic phenotype, and diverse antigen specificity present major challenges to harnessing this potent tolerogenic population to treat autoimmunity and transplant rejection. In this study,
Autor:
Greg Szot, Judy Smith, Ping Zhou, Craig B. Thompson, Qizhi Tang, Maria-Luisa Alegre, Jeffrey A. Bluestone, Kammi J. Henriksen
Publikováno v:
The Journal of Immunology. 170:1510-1516
FcR-binding “classical” anti-CD3 mAb is a potent immunosuppressive drug that alters CD4+ and CD8+ T cell function in vivo via anergy induction and programmed cell death (PCD). Anti-CD3-mediated PCD was Fas independent but was mediated by the mito
Autor:
Gang He, Michael J. Grusby, Kenneth A. Newell, Oliver Kim, J. Richard Thistlethwaite, Ping Zhou, Maria-Luisa Alegre, Jeffrey A. Bluestone, Jun Wang, Zhong Guo, Greg Szot
Publikováno v:
The Journal of Immunology. 165:5580-5587
STAT4−/− mice have impaired type 1 T cell differentiation, whereas STAT6−/− mice fail to generate type 2 responses. The role of type 1 and type 2 T cell differentiation in acute cardiac allograft rejection and in the induction of tolerance wa
Autor:
James L. Riley, M A Mintz, Jeffrey A. Bluestone, Amy L. Putnam, Andrew Medvec, Adam Laing, Giovanna Lombardi, Karim Lee, Robert I. Lechler, M Wray, Qizhi Tang, E Trotta, Angela P. Lares, M Laszkowska, Greg Szot, Niloufar Safinia, Weihong Liu
Publikováno v:
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, vol 13, iss 11
Putnam, AL; Safinia, N; Medvec, A; Laszkowska, M; Wray, M; Mintz, MA; et al.(2013). Clinical grade manufacturing of human alloantigen-reactive regulatory T cells for use in transplantation. American Journal of Transplantation, 13(11), 3010-3020. doi: 10.1111/ajt.12433. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/2vh9v3tq
Putnam, AL; Safinia, N; Medvec, A; Laszkowska, M; Wray, M; Mintz, MA; et al.(2013). Clinical grade manufacturing of human alloantigen-reactive regulatory T cells for use in transplantation. American Journal of Transplantation, 13(11), 3010-3020. doi: 10.1111/ajt.12433. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/2vh9v3tq
Regulatory T cell (Treg) therapy has the potential to induce transplantation tolerance so that immunosuppression and associated morbidity can be minimized. Alloantigen-reactive Tregs (arTregs) are more effective at preventing graft rejection than pol
Autor:
Carol Smith, Jose Oberholzer, Cheryl Durkop, Jonathan R. T. Lakey, Elsie Sanders, Tara L. McCready, Michael J. Thompson, Kim Rusk, Charles Owens, Patrick Zhao, Lorraine Lesiecki, Mark S. Cattral, Debbie Ramos, Chandra Trasbourg, Andrew Heitman, Jennifer Bishop, Laura O'Brien, Heather Turgeon, Angie Korsun, Enrico Benedetti, Arlene LaRose, Yvette Blanco-Jivanjee, Suzanne Pellar, Maria I. Perez, Franca B. Barton, Michael Worden, Christina Mandzuk, Antony Valentine, Violeta Raverdy, Charlotte Garwood, Ryan Skarbek, Grace Sauzier, Terri Baker, Dan Fraga, Mark A. Hardy, Barbara Culbreath, Pablo Cure, William Marks, Muhammed Hafiz, Janet Wright, Elizabeth Wright, Ena Poumian Ruiz, Diane K. McLaughlin, Shama Bader, Jenny Joseph, Peter G. Stock, Barbara Reswell, Dianne Donat, Chuck Wagner, Jeff Ansite, R.J. Ketchum, Julia Santiago, Steve Wease, Ruth Danoff, Lesley E. Adcock, Eather Sours, Ali Naji, David M. Radosevich, James Bui, Kathy Duderstadt, James Cravens, Derek West, Julie Kerr-Conte, Eileen Markmann, Maral Palanjian, David A. Baidal, Dixon B. Kaufman, Marie-Christine Vantyghem, Greg Szot, Travis Romagnoli, Rodolfo Alejandro, Carrie Gibson, Heather Robertson, Jill Sheedy, Vijay Menon, Camillo Ricordi, Arthur Dea, Jacqueline Cereijo, Fouad Kandeel, Valery Gmyr, Shelly Baker, Shaopeng Deng, Pam Boone, Karyn Nash, Dylan M. Zylla, Susan George, Marti H. Sears, Paige Schock, Jeffrey A. Bluestone, Nancy Radke, Joan Kelly, Joan McElroy, Virgil Larson, Kathleen LaBranche, Qiongfen Guo, Bashoo Naziruddin, Keiko Omori, Barbara Olack, Betsy Britz, Shameka Thomas, Bernhard J. Hering, P. F. Gores, Wendy Bourne, Leonard Chen, Enrico Cagliero, Robin L. Jevne, Amy Mote, Andrew M. Posselt, Payam Salehi, Jeanette Hacker, Kenneth L. Brayman, Gordon C. Weir, Bryan Calaway, Piotr Witkowski, Deana Williams, Maricruz Silva-Ramos, Patrice Al-Saden, Carol Kramer, John A. Goss, Jose Avila, François Pattou, Marlon F. Levy, Elyse Stuart, K. D. Shiang, Susan Comninel, Mark B. Lockwood, Yoko Mullen, Parastoo Dinyari, Niraj M. Desai, Shannon Inman, Tiffany Zgabay, David Iklé, Donald Stablein, Monalee Shah, Agnes Lo, Elizabeth Holbrook, Jamen Parkey, Nina Reinhart, Barb Bland, Lori Otken, Rimed Ezzouaoui, Amy Wallace, Debra Kemp, Aldo A. Rossini, A. M. James Shapiro, Donna Sarmon, Tatiana Froud, Peggy Murphy, Melissa Roberts, Donna Bogard, Anne Nettles, Kimber Westbrook, Michael Hanschew, Tara Rojas, Bonnie Olszewski, Melissa McGraw, Kamel Sadat, Carla J. Greenbaum, A. Osama Gaber, Betul Hatipoglu, Yamini Damodharan, Gary A. Levy, Marc R. Garfinkel, Laurie Weiner, Marli McCulloch-Olson, Deborah McGee-Wilson, Alexander C. Wiseman, Jeffrey Longmate, Jess Long, Joan Martellotto, Michael Hansen, A. Kadir Omer, Ronald G. Gill, Winsor Simmons, Edmond A. Ryan, Kevan C. Herold, Lisa Rothenberg, Deborah Spindler, Sarah E. Goodpastor, Matthew S. Hanson, Zhuoru Liu, Celia Hartigan, Linda Langman, Aisha Khan, Kathy Hodges, Darrell Grimes, Bruce Carveth, Craig Smith, Bruce Kaplan, Marilyn Reeve, Matthew Connors, Christopher N. Larsen
Publikováno v:
Cell Transplantation, Vol 18 (2009)
As of October 1, 2007, 25 North American medical institutions and one European islet transplant center reported detailed information to the Registry on 315 allograft recipients, of which 285 were islet alone (IA) and 30 were islet after kidney (IAK).
Autor:
Mahesh Yadav, Greg Szot, Holger Russ, Tingxia Guo, Stephen Stephan, Evert Kroon, Eugene Brandon, Kevin D'Amour, Mathias Hebrok, Jeffrey Bluestone
Publikováno v:
The Journal of Immunology. 190:69.53-69.53
Regulatory T cells (Tregs) are potent suppressor of adverse immune reaction and have shown lot of promise in the preclinical studies for the treatment of autoimmune diseases and organ transplantation. In the current study we tested if ex vivo expande