Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Greg Petruncio"'
Autor:
Greg Petruncio, Zachary Shellnutt, Lauren L. Young, Michael Girgis, Wendy K. Strangman, R. Thomas Williamson, Kylene Kehn-Hall, Mikell Paige
Publikováno v:
ACS Omega, Vol 9, Iss 28, Pp 30993-30997 (2024)
Externí odkaz:
https://doaj.org/article/accb0649445a4006be85232d7b57c277
Autor:
Kyung Hyeon Lee, Nadia Fazal Ali, Soo Hyeon Lee, Zhimin Zhang, Marie Burdick, Zachary J. Beaulac, Greg Petruncio, Linxia Li, Jiangdong Xiang, Ezra M. Chung, Kenneth W. Foreman, Schroeder M. Noble, Yun M. Shim, Mikell Paige
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract The aminopeptidase activity (AP) of the leukotriene A4 hydrolase (LTA4H) enzyme has emerged as a therapeutic target to modulate host immunity. Initial reports focused on the benefits of augmenting the LTA4H AP activity and clearing its putat
Externí odkaz:
https://doaj.org/article/5e035599853c418c91141324ae6d3acc
Publikováno v:
Natural Product Reports. 38:2187-2213
Covering: 2000-2020The 1,4-diene motif, also known as a skipped diene, is widespread across various classes of natural products including alkaloids, fatty acids, terpenoids, and polyketides as part of either the finalized structure or a biosynthetic
Autor:
Amanda Shim, Kyung Hyeon Lee, Zhimin Zhang, Mikell Paige, Schroeder M. Noble, Yun M. Shim, Greg Petruncio, Marie D. Burdick
Publikováno v:
Journal of Medicinal Chemistry. 62:10605-10616
Activation of the leukotriene A4 hydrolase (LTA4H) aminopeptidase (AP) activity with 4-methoxydiphenylmethane (4MDM) promoted resolution of neutrophil infiltration in a murine cigarette smoke-induced model for emphysematous chronic obstructive pulmon
Autor:
Kyung Hyeon, Lee, Nadia Fazal, Ali, Soo Hyeon, Lee, Zhimin, Zhang, Marie, Burdick, Zachary J, Beaulac, Greg, Petruncio, Linxia, Li, Jiangdong, Xiang, Ezra M, Chung, Kenneth W, Foreman, Schroeder M, Noble, Yun M, Shim, Mikell, Paige
Publikováno v:
Scientific reports. 12(1)
The aminopeptidase activity (AP) of the leukotriene A
Autor:
Carolina Salvador-Morales, Kathleen K Harnden, Lei Li, Greg Petruncio, Deepanjali Patil, Lihong V. Wang, Jisha V Somasekharan, Mikell Paige
Publikováno v:
ACS Nano
One of the primary challenges in breast cancer diagnosis and treatment is intratumor heterogeneity (ITH), i.e., the co-existence of different genetically and epigenetically distinct malignant cells within the same tumor. Thus, the identification of I
Autor:
Kyung Hyeon, Lee, Greg, Petruncio, Amanda, Shim, Marie, Burdick, Zhimin, Zhang, Yun M, Shim, Schroeder M, Noble, Mikell, Paige
Publikováno v:
Journal of medicinal chemistry. 62(23)
Activation of the leukotriene A
Publikováno v:
Tetrahedron Letters. 86:153516
The aromatic ring in benzyl halides and sulfonates imparts unique reactivity at the benzylic carbon atom. Photoredox sp3-sp3 cross-coupling proved ineffective for coupling p-methoxybenzyl chloride (PMBCl), leading to a new strategy for the sp3-sp3 cr
Publikováno v:
Tetrahedron Letters. 61:152547
Batatasin IV is a dihydrostilbenoid isolated from Chinese yams which was shown to have inhibitory activities against plant growth. Later studies showed that this compound may exhibit anti-inflammatory properties by inhibiting the epoxide hydrolase ac