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pro vyhledávání: '"Greg Ngo"'
Autor:
Eva-Maria Holstein, Greg Ngo, Conor Lawless, Peter Banks, Matthew Greetham, Darren Wilkinson, David Lydall
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 7, Iss 7, Pp 2375-2389 (2017)
Functional telomeres are critically important to eukaryotic genetic stability. Scores of proteins and pathways are known to affect telomere function. Here, we report a series of related genome-wide genetic interaction screens performed on budding yea
Externí odkaz:
https://doaj.org/article/0f342c97faf94badaa0e039418d933b3
Autor:
Christopher Parker, Adam C. Chambers, Dustin J. Flanagan, Jasmine Wing Yu Ho, Tracey J. Collard, Greg Ngo, Duncan M. Baird, Penny Timms, Rhys G. Morgan, Owen J. Sansom, Ann C. Williams
Publikováno v:
Parker, C, Chambers, A C, Flanagan, D J, Ho, J W Y, Collard, T J, Ngo, G, Baird, D M, Timms, P, Morgan, R G, Sansom, O J & Williams, A C 2022, ' BCL-3 loss sensitises colorectal cancer cells to DNA damage by targeting homologous recombination ', DNA repair, vol. 115, 103331 . https://doi.org/10.1016/j.dnarep.2022.103331
The proto-oncogene BCL-3 is upregulated in a subset of colorectal cancers (CRC), where it has been shown to enhance tumour cell survival. However, although increased expression correlates with poor patient prognosis, the role of BCL-3 in determining
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5b79364554502afec628f6dd8f54280